The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 155)
Rapid Response Innovation Awards, 2014
Although the causes of Parkinson's disease (PD) are yet unknown, the overall health of the body likely plays a major role in disease initiation and progression. However, maintenance and/or restoration of normal systemic activity have been largely overlooked by current pharmaceutical treatments — an approach that has led to a scarcity of effective disease-modifying ...
Access to Data and Biospecimens, 2014
We have discovered a long, non-coding RNA (RNA that does not encode a protein) that shows a five-fold decrease within the brains of people with Parkinson's disease (PD) compared to similarly aged healthy individuals. This RNA is also found within human blood, and we hope that its level in blood could serve as a peripheral PD biomarker. Validation of a biological marker of PD...
Researchers: Antony A. Cooper, PhD
Biomarkers Across Neurodegenerative Diseases, 2014
We know that both Alzheimer's and Parkinson's diseases affect certain parts of the brain first, before affecting the rest of the brain, and often before people start to show signs of the disease. These brain structures can be analyzed precisely in a living person using 3D MRI imaging and computer algorithms. Studying changes in the shape of these structures — suc...
Research Grant, 2014
Mutations in GBA1, the gene encoding the protein glucocerebrosidase, represent a common genetic risk factor for developing Parkinson disease (PD). PD patients with and without GBA1 mutations exhibit lower levels of glucocerebrosidase in the central nervous system (CNS), suggesting a strong correlation between low glucocerebrosidase activity and the development of t...
Researchers: Sergio Pablo Sardi, PharmD, PhD
Parkin Biology, 2014
The protein Parkin contributes to the elimination of damaged mitochondria by a process called mitophagy. Prior research has shown that silencing Parkin gene affects innate immunity, the first line of defense against invading viruses. This project will characterize the mechanisms by which Parkin modulates host immune response. One of the key players in innate immunity is a mitoc...
Researchers: Aleem Siddiqui, PhD