The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 27)
Computational Science, 2017
Parkinson's disease (PD) progresses differently in every case, which makes reliable prediction of future outcomes challenging. Looking for better ways to predict disease progression, researchers have been trying to identify endpoints, or specific clinical signs, symptoms or test results that people living with PD would have at some point in the future. To do this, researchers firs...
Researchers: Jacquelyn Cragg, MPH, PhD
Target Advancement Program, 2016
Genetic mutations that alter the function of the LRRK2 protein increase the risk of developing a form of Parkinson's disease (PD). Age and other environmental factors combine with genetic risk factors to result in the disease. One of the pathological hallmarks of PD is the presence of protein clumps that appear in brain cells, composed of alpha-synuclein and LRRK2. Recent work has...
Researchers: Austen James Milnerwood, PhD
Research Grant, 2016
Promising Outcomes of Original Grant:
We hypothesized in the original funded grant that evaluation of texture and variability, beyond conventional averaging of voxel (element of space) intensities within a region of interest in dopamine transporter (DAT) SPECT (brain imaging technique) images, could provide improved correlations with clinical measures, such as the unified Parkinson's disease (PD) r...
Research Grant, 2015
Recent studies have revealed a role for PINK1 and PARKIN, two genes mutated in early onset Parkinson's disease, function to promote a cellular process called ubiquitylation of mitochondrial outer membrane proteins. This process promotes natural and healthy degradation of mitochondria. This study will develop a platform for quantification of PINK1-PARKIN activity in cells and...
Researchers: J. Wade Harper, PhD
Improved Biomarkers and Clinical Outcome Measures, 2015
Validation of a Performance-based Assessment of Functional Ability Related to Cognition in Parkinson's Disease
There is a pressing need for new treatments to address cognitive impairment in Parkinson's disease, yet there is no consensus on how to best evaluate their effectiveness. Treatment trials to date mainly use cognitive testing but improvement on such tests has questionable clinical or practical benefits. Functional assessments, which evaluate the ability to perfor...