The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 54)
Research Grant, 2015
Unified Dyskinesia Rating Scale: Application for FDA Designation as a Preferred Scale for Assessing Dyskinesia in Parkinson's Disease
Several scales are available for the rating of dyskinesia in Parkinson's disease, and the designation of a single preferred scale for studies of new treatments will allow different treatments to be compared in a uniform manner with a single measurement tool that best fits the needed criteria to asses all aspects of dyskinesia.
Given the strong clinimetric profile of th...
Rapid Response Innovation Awards, 2014
Pramipexole (Mirapex) is a drug that is effective at alleviating movement deficits associated with Parkinson's disease. However, pramipexole can induce compulsive behaviors and behavioral addictions, such as problem gambling, in some patients. Mirtazapine, an atypical antidepressant reduces the effects of drug addiction in pre-clinical models and in humans. This st...
Research Grant, 2014
Apomorphine is a drug that is used to control "off" episodes in people with Parkinson's disease. At present, the drug is given by injection under the skin and starts to relieve symptoms within 20-30 minutes. APL-130277 is a new formulation of apomoprhine that is given as a thin-strip film that is placed under the tongue. APL-130277 appears to work as quickly as t...
Researchers: Albert Agro, PhD
Research Grant, 2013
Promising Outcomes of Original Grant:
Intrapulmonary delivery of levodopa results in rapid, consistent and predictable augmentation of plasma levodopa levels in both healthy volunteers and subjects with Parkinson's disease. The unique pharmacokinetic profile translates into rapid and durable improvement in motor function without worsening dyskinesia in Parkinson's patients. Results from prior clini...
Dyskinesia LEAPS, 2012
Dyskinesia is a term used to describe involuntary movements that develop as side effects of dopamine drugs used to treat Parkinson's disease. Dyskinesias are frequent and disabling to many patients. They can interrupt smooth coordinated movements, affect communication and disrupt activities of daily living. Currently, among medications to treat dyskinesia, only amantadine is e...