The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 118)
Research Grant, 2018
There is a pressing need for Parkinson's disease (PD) biomarkers -- objective measures of disease -- that will enable early and accurate diagnosis and allow to track disease progression and therapeutic improvement. We have developed a new mathematical method to characterize PD-related brain networks. This method is based on a mathematical analysis of data collected via resting sta...
Improved Biomarkers & Clinical Outcome Measures, 2017
Dopamine Buffering Capacity Measured by phMRI as a Novel Biomarker of Disease Progression in Parkinson's Disease
This project will test a new idea for measuring the severity of Parkinson's disease (PD). The brain acts as if it can store each dose of levodopa (L DOPA) for a short period of time and lets it "leak" into the brain when needed. This levodopa reservoir appears to get "leakier" as PD progresses, contributing to a gradually briefer benefit from each dose of the drug. The new idea we...
Researchers: Kevin J. Black, MD
Research Grant, 2017
Assessing the accumulation of tau (protein associated with dementia) and alpha-synuclein (sticky protein associated with Parkinson's) in the living human brain is crucial to better understanding Progressive Supranuclear Palsy (movement disorder that causes impaired balance and vision; PSP), Parkinson's disease (PD) and related neurodegenerative disorders, in addition to aiding in ...
Researchers: Neil Vasdev, PhD
Research Grant, 2017
Promising Outcomes of Original Grant:
Our project aims to develop a brain imaging agent for alpha-synuclein, a key protein involved in Parkinson's disease (PD) pathology. Such an agent will help (i) diagnose PD earlier, (ii) track pathology over time and (iii) monitor the efficacy of therapeutics reducing alpha-synuclein aggregates. The AC Immune team identified promising compounds they are refinin...
Computational Science 2017, 2017
Because Parkinson's disease (PD) affects people around the world regardless of their ethnicity or place of residence, research to find a cure for Parkinson's is truly an international effort. We aim to support this effort by creating the largest international database of brain images from people with and without PD. We will search these images for variations in the brains of peopl...
Researchers: Neda Jahanshad, PhD