The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 27)
PPMI Data Challenge, 2016
As Parkinson's disease (PD) is highly heterogeneous, identifying coherent PD subtypes is crucial for understanding the underlying mechanism of the disease and designing and testing appropriate therapies. Existing studies mostly focus on discovering static patterns among PD patients with vector-based models. However, the disease progression patterns of PD patients could also be very...
Therapeutic Pipeline Program, 2015
Alpha4Beta2 Nicotinic Agonist for Treatment of L-Dopa Refractory Gait and Balance Disorders in Parkinson Disease
Gait and balance problems, particularly falls, are common and disabling symptoms in Parkinson disease (PD), and do not improve markedly with existing treatments. Studies have indicated that loss of the brain chemical messenger acetylcholine causes gait and balance problems in PD. A widely used FDA-approved drug, varenicline, mimics some of the important actions of acetylcholine. Us...
Access to Data and Biospecimens, 2014
Although Parkinson's disease (PD) is diagnosed as a movement disorder, motor deficits are preceded by non-motor features including cognitive, cardiovascular, gastrointestinal, psychiatric and sleep disturbances. Characterizing patterns of such non-motor features in early, medication-nave PD may allow for improved treatment.
This study will use cluster anal...
Researchers: Samay Jain, MD, MS
Rapid Response Innovation Awards, 2014
The Microbiome in Parkinson's Disease: Role as a Potential Biomarker and Relation to Disease Progression
Promising Outcomes of Original Grant:
In their previous study these researchers investigated whether the abundance of different microbes in the gut differs between Parkinson's disease (PD) patients and control subjects. They found that in particular one species was significantly reduced in PD patients and that the levels of another species were associated with certain PD symptoms. These results are...
MJFF Research Grant, 2013
A New Tool for CSF-Based Parkinson Disease Diagnostics: Super-Resolution Microscopy Investigation of Alpha-Synuclein Aggregates
It is still difficult to diagnose Parkinson's Disease (PD) patients through routine assays. Clinical research on PD suggests that the aggregation (clumping) of the protein alpha-synuclein is a good indicator of PD. The main difficulty is to identify the aggregates of synuclein, since these clumps of protein are much smaller than what a normal microscope can detect...