The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 24)
Research Grant, 2014
Parkinson's disease (PD) is associated with the presence of protein aggregates in the form of Lewy bodies composed of the protein alpha-synuclein. One of the greatest obstacles for developing a disease-modifying therapy for PD is the lack of early diagnosis. To date, there is no definite, sensitive and predictive laboratory test available that can identify indivi...
Researchers: Claudio Soto, PhD
Rapid Response Innovation Awards, 2014
Loss of dopaminergic neurons is seen in Parkinson's disease, and transplantation of these neurons can greatly ease symptoms. However, several major drawbacks are associated with transplantation-based therapy, begging for alternatives to treat Parkinson's. Cutting-edge research shows that the fate of cells can be re-engineered in the adult brain, raising the hope of using a patient'...
Rapid Response Innovation Awards, 2013
Evaluation of Targeted Plasticity Therapy as a Treatment for Motor Dysfunction in Parkinson's Disease
Deterioration of motor function is a debilitating symptom of Parkinson's disease (PD). We have recently developed a novel method that utilizes stimulation of the vagus nerve delivered during rehabilitative training to improve motor function after various types of brain injury. Vagus nerve stimulation (VNS) enhances plasticity, or the ability to change, within ne...
MJFF Research Grant, 2013
The accumulation of tau protein is an important pathogenic factor in Parkinson's disease (PD) and other neurodegenerative disorders. Our recent findings from pre-clinical models and human brain tissues suggest that tau oligomers (comprised of two or more tau molecules) play a key role in eliciting Parkinson`s disease. In this project, we will target these toxic species via pa...
Researchers: Rakez Kayed, PhD
Research Grant, 2013
The protein alpha-synuclein aggregates abnormally in brain tissue affected by Parkinson's disease. The present project is a follow up on a project that generated a panel of antibodies that recognize aggregated alpha-synuclein. The present project will characterize these antibodies for their qualities in recognizing aggregates of alpha-synuclein in brain tissue and ...