Constipation is a non-motor symptom of Parkinsonís disease that causes great discomfort and can decrease the bodyís ability to absorb medicine used to treat the disease.
A new study now enrolling patients is testing a drug to treat chronic constipation in Parkinsonís patients.
The MOVE-PD study ó led by Dr. Ronald Pfeiffer of the Parkinson Study Group and supported by The Michael J. Fox Foundation ó is now recruiting at sites in:
- Englewood, Colorado
- Augusta, Georgia
- Scarborough, Maine
- East Lansing, Michigan
- West Bloomfield, Michigan
- Rochester, New York
Additional sites at the following locations will start recruiting soon:
- Summit, New Jersey
- Portland, Oregon
- Philadelphia, Pennsylvania
Parkinsonís patients not satisfied with current treatment for chronic constipation will receive both a placebo and the drug RM-131 over the course of the study. Theyíll submit daily diaries on bowel habits and abdominal symptoms and undergo clinical assessment at five study visits.
The investigators hope to show that RM-131 improves the symptoms of constipation in Parkinsonís disease, especially among patients who do not respond to other treatments.