We understand that it can be challenging to gain clarity and perspective on breaking Parkinson's news. Q&As in this section are conducted with leading experts in the Parkinson's disease research field to quickly provide an informed, impartial opinion on new findings -- and to get to the bottom of what they might mean for researchers and people living with PD today.
Creating Stem Cells from Skin Cells: Promise, Limitations and Implications for Parkinson's Disease Research
November 20, 2007
On Tuesday, November 20, news media around the world reported that two research teams, led by Shinya Yamanaka at Kyoto University in Japan and James Thomson at the University of Wisconsin, working with human adult skin cells, had generated cells with many of the physical, growth and genetic features typically found in embryonic stem cells. Known as "induced pluripotent stem cells" or iPS cells, these new cells can differentiate to produce other tissue types, including what appear at first glance...Read More
June 22, 2007
On Friday, June 22, news outlets reported the publication in the journal Lancet of results from a Phase 1 trial conducted to determine the safety of a novel gene therapy approach to Parkinson's. The trial, conducted in 12 patients, determined that the approach was safe, and researchers also reported that it seemed to improve PD symptoms without causing side effects.
The Michael J. Fox Foundation spoke to Thomas Wichmann, MD, associate professor of neurology at Emory University in Atlanta, Ge
June 21, 2007
On June 15, Mayo Clinic researchers published a paper in the journal PLoS Genetics reporting that genetic changes within a group of genes that control how brain cells reach out and connect with other brain cells had been linked to as much as a 90-fold increase in the risk of Parkinson's disease for some people. The new paper builds on results of earlier work funded by The Michael J. Fox Foundation.
To gain a clearer understanding of the new findings and their implications both for people living...Read More
May 17, 2007
On May 15, 2007, news outlets all over the world reported results from a recent clinical trial on the effects of Coenzyme Q10 (CoQ10) in Parkinson's disease. Specifically, researchers found that CoQ10 does not exert a beneficial effect on PD symptoms. This information may seem surprising in light of the results of an earlier Phase II clinical trial suggesting that CoQ10 slowed functional decline in Parkinson's, which has prompted the National Institute of Neurological Disorders and Stroke (NIN...
March 30, 2007
On Thursday, March 29, the FDA announced that it would pull the Parkinson's drug pergolide, marketed under the name Permax and as generics, from the market as a result of persuasive evidence that it can lead to heart valve disease.
The Michael J. Fox Foundation spoke to Irene Hegeman Richard, MD, associate professor of neurology and psychiatry at the University of Rochester and a member of the Foundation's Scientific Advisory Board, about the decision to pull the drug and the best course of act...Read More