Robert H. Mach, PhD
Professor at Washington University School of Medicine
Location: St. Louis, Missouri, United States
Dr. Mach has over 25 years experience in the development of radiotracers for PET and SPECT. He has been the director of the Washington University Cyclotron Facility since 2004; and, since 2007, has headed of the Radiological Chemistry Lab in the Division of Radiological Sciences at the Mallinckrodt Institute of Radiology. Dr. Mach currently leads a multi-disciplinary research program aimed a developing PET radiotracers for imaging cell proliferation, dopamine receptor dysregulation in CNS disorders, mechanisms of cell death, oxidative stress, and cardiovascular disease. He has developed two radiotracers which are currently being evaluated in clinical imaging studies: 1) [18F]ISO-1 for imaging cell proliferation in lymphoma, breast, and head & neck cancer; and, 2) [18F]NOS for imaging iNOS activation in heart transplant patients. Clinical PET studies with a third radiotracer developed in his lab ([18F]FAA) for imaging fatty acid metabolism in type 2 diabetes mellitus will be initiated later this year.