The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarker Development, 2015Comparison of Pre- and Post-mortem Cerebrospinal Fluid Levels of Proteins and Lipids
Study Rationale:
Alpha-synuclein aggregation in the brain is the main pathology of Parkinson’s disease (PD). Cerebrospinal fluid (CSF) levels of alpha-synuclein are lower in PD. It... -
Dyskinesia Challenge, 2015Biomarkers and Sensors for Levodopa-induced Dyskinesia
Study Rationale:
Levodopa is the gold-standard drug for treatment of Parkinson’s disease (PD), but chronic use is associated with serious motor complications called levodopa-induced... -
Dyskinesia Challenge, 2015Targeting M4 Muscarinic Receptors for the Treatment of Levodopa-induced Dyskinesia
Study Rationale:
Levodopa-induced dyskinesia is thought to stem from sustained stimulation of D1 dopamine receptors (D1Rs). One potential strategy for diminishing excessive D1R... -
Access to Data and Biospecimens, 2015New Tools for Direct Visualization of Individual Oligomers in Human Biofluids
Objective/Rationale: We have developed a completely new optical technique called SOAP imaging (single oligomers of amlyoidigenic proteins). This can be used to directly visualize the protein clumps...
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Access to Data and Biospecimens, 2015BioFIND: Analysis of A-beta, Tau and P-tau in CSF Samples
Study Rationale: Mixed pathology is common in all neurodegenerative diseases including Parkinson’s disease (PD). Three cerebrospinal fluid (CSF) biomarkers, Ab1-42, t-tau and p-tau181, provide an...
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Access to Data and Biospecimens, 2015Immunogenetic Determinants of Disease Risk in Parkinson’s Disease
Study Rationale:
There is growing indication that the immune system plays a role in the development and progression of Parkinson’s disease with recent genome-wide association studies identifying...
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Our funding programs support basic, translational and clinical research from academia and industry.