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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Sphingolipid and Alpha-synuclein Interactions

    Study Rationale:                   
    The contributions of multiple factors to Parkinson's disease (PD) are not fully understood.  However, it is clear that a normal cellular protein called alpha...


    Year Funded: 2019
  • Biomaterial-enhanced Cellular Brain Repair for Parkinson's Disease

    Study Rationale:
    One promising approach for the treatment of Parkinson’s is to replace the cells that have died in the disease through transplantation of healthy cells into the brain. However, this...


    Year Funded: 2019
  • Study in Finnish Population to Identify Therapies with Repurposing Potential for Parkinson’s Disease

    Study Rationale:
    Effective treatments for slowing the progression of Parkinson’s disease are urgently needed. Searching for possible treatments among drugs already used for other indications is a...


    Year Funded: 2019
  • Study in Norwegian Population to Identify Therapies with Repurposing Potential for Parkinson’s Disease

    Study Rationale:
    There are not yet medicines that can prevent or slow Parkinson’s disease. Developing a new therapeutic can cost up to 2.6 billion dollars and takes many years of screening, chemistry...


    Year Funded: 2019
  • Managing Levodopa-induced Dyskinesias by Targeting Dopamine D1 Receptor Signaling

    Study Rationale:
    Parkinson’s is a complex brain disease caused by the gradual loss of brain cells producing the neurotransmitter dopamine, which controls movement, emotion and affect. However,...


    Year Funded: 2019
  • Small Molecule Therapeutics Targeting Nurr1

    Study Rationale:
    Nurr1 is a protein that plays critical roles in the development, maintenance and survival of dopaminergic neurons and, as such, is a potential therapeutic target for treating the...


    Year Funded: 2019
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