About the Study
Launched in 2012, BioFIND is a collaboration between MJFF and the National Institute of Neurological Disorders and Stroke (NINDS). The study aims to complement PPMI to produce the most comprehensive and long-ranging dataset available for biomarker discovery work throughout the PD community. BioFIND consisted of a dynamic infrastructure comprised of the principal investigator, site investigators, Clinical Core, Biorepository Core and Bioinformatics Core. This section of the website is designed to provide insight into the study design and to provide access to primary study documents.
BioFIND was designed with a strong focus on developing standardized protocols, policies, systems and processes. To achieve successful implementation of this across the clinical sites and cores, the study leadership has led the development of an extensive study protocol, data collection standards and processes, and data and biospecimen use agreements and policies. All of these documents support the collection, transfer and storage of clinical data and biological samples.
|Study Leadership||Un Kang, MD (Columbia University Medical Center, New York, NY)|
|Site Investigators||Roy Alcalay (Columbia University Medical Center, New York, NY)
Amy Amara (University of Alabama at Birmingham, Birmingham, AL)
Sam Frank (Boston University, Boston, MA)
Jennifer Goldman (Rush University Medical Center, Chicago, IL)
Claire Henchcliffe (Cornell University Medical Center, New York, NY)
Penelope Hogarth (Oregon Health and Science University, Portland, OR)
Paul Tuite (University of Minnesota Medical Center, St. Paul, MN)
Tao Xie (University of Chicago Medical Center, Chicago, IL)
|Clinical Core||The Clinical Core, the Clinical Trials Coordinating Center (CTCC) at the University of Rochester managed the clinical sites and performed quality control on the clinical data.|
|Biorepository Core||The Biorepository Core, NINDS Repository at Indiana University, received, and now stores and distributes, biospecimens collected throughout the course of the study.|
|Bioinformatics Core||The Bioinformatics Core, the Laboratory of Neuroimaging (LONI) at the University of California Los Angeles, designed and maintains the external BioFIND study database.|