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Role of Gad1 in l-DOPA-induced dyskinesias
… years also induces severe secondary effects known as dyskinesia. Such secondary effects seriously limit the … that this manipulation does not prevent levodopa-induced dyskinesias. This result, however, does not completely rule …
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Combined Therapy with Amantadine and Fenobam for Levodopa-induced Dyskinesia
… the only available medication to treat levodopa-induced dyskinesia: involuntary, jerky movements caused by long-term … levodopa. However, the dose of amantadine that helps treat dyskinesia is associated with side effects such as cognitive …
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Development of a Treatment for Dyskinesia Targeting Opioid Receptors
… Objective/Rationale: Levodopa-induced dyskinesias (LID) affect the majority of patients with …
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Gene-to-gene Interaction Analysis of Levodopa-induced Dyskinesia
… Long-term treatment for Parkinson’s with levodopa can cause dyskinesia or involuntary movements. Other drugs like … of specific gene variations could predict the appearance of dyskinesia. Study Design: We will use DNA extracted from the …
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Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease
… Objective/Rationale: Dyskinesia is a term used to describe involuntary movements … of dopamine drugs used to treat Parkinson's disease. Dyskinesias are frequent and disabling to many …
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Xenon Inhalation to Reduce L-DOPA-Induced Dyskinesia
… however long-term use leads to disabling L-DOPA-induced dyskinesia (LID) in the vast majority of patients. NMDA … or avoiding treatment-induced complications such as dyskinesia, which affects the long term efficacy of the …