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  • Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson’s disease
    2024
    OPEN
    Title: Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson’s disease
    Author(s): Verena Pesch, José Miguel Flores-Fernández, Sara Reithofer, Liang Ma, Pelin Özdüzenciler, Yannick Busch, Aishwarya Sriraman, Yongliang Wang, Sara Amidian, Chiara V M Kroepel, Laura D. Müller, Yi Lien, Olivia Rudtke, Benedikt Frieg, Gunnar F. Schröder, Holger Wille, Gültekin Tamgüney
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 147
    Issue #: 5
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1093/brain/awae061
    Best OA location URL:
    Citation Count: 2
  • Adoptive transfer of mitochondrial antigen-specific CD8+ T-cells in mice causes parkinsonism and compromises the dopamine system
    2024
    RESTRICTED
    Title: Adoptive transfer of mitochondrial antigen-specific CD8+ T-cells in mice causes parkinsonism and compromises the dopamine system
    Author(s):
    Journal Name:
    Publisher: Cold Spring Harbor Laboratory
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1101/2024.02.26.582098
    Best OA location URL:
    Citation Count:
  • Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
    2024
    RESTRICTED
    Title: Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
    Author(s):
    Journal Name:
    Publisher: Cold Spring Harbor Laboratory
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1101/2024.02.26.582055
    Best OA location URL:
    Citation Count:
  • Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism
    2024
    RESTRICTED
    Title: Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism
    Author(s):
    Journal Name:
    Publisher: Cold Spring Harbor Laboratory
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1101/2024.02.25.581985
    Best OA location URL:
    Citation Count:
  • Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress
    2024
    OPEN
    Title: Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress
    Author(s): Mohamed A. Eldeeb, Andrew N. Bayne, Armaan Fallahi, Thomas Goiran, Emma J. MacDougall, Andrea Soumbasis, Cornelia E. Zorca, Jace-Jones Tabah, Rhalena A. Thomas, Nathan Karpilovsky, Meghna Mathur, Thomas M. Durcan, Jean‐François Trempe, Edward A. Fon
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 121
    Issue #: 10
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1073/pnas.2313540121
    Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.2313540121
    Citation Count: 6
  • Identification of 27 allele-specific regulatory variants in Parkinson’s disease using a massively parallel reporter assay
    2024
    OPEN
    Title: Identification of 27 allele-specific regulatory variants in Parkinson’s disease using a massively parallel reporter assay
    Author(s): Sophie Farrow, Sreemol Gokuladhas, William Schierding, Michael Pudjihartono, Jo K. Perry, Antony A. Cooper, Justin M. O’Sullivan
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-024-00659-5
    Best OA location URL:
    Citation Count: 1
  • Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI
    2024
    RESTRICTED
    Title: Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI
    Author(s): Alyssa H. Zhu, Talia M. Nir, Shayan Javid, Julio E. Villalon‐Reina, Amanda Rodrigue, Lachlan T. Strike, Greig I. de Zubicaray, Katie L. McMahon, Margaret J. Wright, Sarah E. Medland, John Blangero, David C. Glahn, Peter Kochunov, Asta Håberg, Paul M. Thompson, Neda Jahanshad
    Journal Name:
    Publisher: Cold Spring Harbor Laboratory
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1101/2024.02.22.581646
    Best OA location URL:
    Citation Count: 0
  • Exploiting macro- and micro-structural brain changes for improved Parkinson’s disease classification from MRI data
    2024
    OPEN
    Title: Exploiting macro- and micro-structural brain changes for improved Parkinson’s disease classification from MRI data
    Author(s): Milton Camacho, Matthias Wilms, Hannes Almgren, Kimberly Amador, Richard Camicioli, Zahinoor Ismail, Oury Monchi, Nils D. Forkert
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-024-00647-9
    Best OA location URL:
    Citation Count: 3
  • GBA1 rs3115534 Is Associated with REM Sleep Behavior Disorder in Parkinson's Disease in Nigerians
    2024
    OPEN
    Title: GBA1 rs3115534 Is Associated with REM Sleep Behavior Disorder in Parkinson's Disease in Nigerians
    Author(s): Oluwadamilola O. Ojo, Sara Bandrés‐Ciga, Mary B. Makarious, Peter Wild Crea, Dena Hernández, Henry Houlden, Mie Rizig, Andrew Singleton, Alastair Noyce, Mike A. Nalls, Cornelis Blauwendraat, Njideka Okubadejo
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 39
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd, cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mds.29753
    Best OA location URL:
    Citation Count: 1
  • Gait patterns during overground and virtual omnidirectional treadmill walking
    2024
    OPEN
    Title: Gait patterns during overground and virtual omnidirectional treadmill walking
    Author(s): Morgan McGrath Lewis, Colin Waltz, Logan Scelina, Kathryn Scelina, Kelsey Owen, Karissa Hastilow, Eric Zimmerman, Anson B. Rosenfeldt, Mandy Miller Koop, Jay L. Alberts
    Journal Name: Journal of NeuroEngineering and Rehabilitation
    Publisher: Springer Science and Business Media LLC
    Vol: 21
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12984-023-01286-6
    Best OA location URL:
    Citation Count: 2
  • Presenilin‐1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage
    2024
    OPEN
    Title: Presenilin‐1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage
    Author(s): Nelly Joseph‐Mathurin, Rebecca L. Feldman, Ruijin Lu, Zahra Shirzadi, Carmen Toomer, John Mallen-St. Clair, Yinjiao Ma, Nicole S. McKay, Jeremy F. Strain, Collin B. Kilgore, Karl A. Friedrichsen, Charles D. Chen, Brian A. Gordon, Gengsheng Chen, Russ C. Hornbeck, Parinaz Massoumzadeh, Austin McCullough, Qing Wang, Yan Li, Guoqiao Wang, Sarah Keefe, Stephanie A. Schultz, Carlos Cruchaga, Gregory M. Preboske, Clifford R. Jack, Jorge J. Llibre‐Guerra, Ricardo Allegri, Beau M. Ances, Sarah Berman, William S. Brooks, David M. Cash, Gregory S. Day, Nick C. Fox, Michael Fulham, Bernardino Ghetti, Keith A. Johnson, Mathias Jucker, William E. Klunk, Christian la Fougère, Johannes Levin, Yoshiki Niimi, Hwamee Oh, Richard J. Perrin, Gerald Reischl, John M. Ringman, Andrew J. Saykin, Peter R. Schofield, Yi Su, Charlene Supnet, Jonathan Vöglein, Igor Yakushev, Adam M. Brickman, John C. Morris, Eric McDade, Johannes Levin, Randall J. Bateman, Jasmeer P. Chhatwal, Tammie L.S. Benzinger
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Vol: 20
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/alz.13729
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.13729
    Citation Count: 2
  • Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease
    2024
    OPEN
    Title: Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease
    Author(s): Peter Kilfeather, Jia Hui Khoo, Katherina Wagner, Han Liang, Maria Claudia Caiazza, Yanru An, Xingju Zhang, Xiaoyan Chen, Natalie Connor‐Robson, Zhouchun Shang, Richard Wade‐Martins
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Vol: 43
    Issue #: 3
    Start Page: 113784
    End Page: 113784
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by, cc-by
    DOI - Digital Object Identifier: 10.1016/j.celrep.2024.113784
    Best OA location URL: http://www.cell.com/article/S2211124724001128/pdf
    Citation Count: 1
  • α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Cav3.2 calcium signaling in astrocytes
    2024
    OPEN
    Title: α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Cav3.2 calcium signaling in astrocytes
    Author(s): Emmanouela Leandrou, Ioanna Chalatsa, Dimitrios Anagnostou, Christina Machalia, Maria Semitekolou, Vicky Filippa, Manousos Makridakis, Antonia Vlahou, Ema Anastasiadou, Kostas Vekrellis, Evangelia Emmanouilidou
    Journal Name: Translational Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Vol: 13
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s40035-024-00401-4
    Best OA location URL: https://doi.org/10.1186/s40035-024-00401-4
    Citation Count: 3
  • Staging of progressive supranuclear palsy-Richardson syndrome using MRI brain charts for the human lifespan
    2024
    OPEN
    Title: Staging of progressive supranuclear palsy-Richardson syndrome using MRI brain charts for the human lifespan
    Author(s): Vincent Planche, Boris Mansencal, José V. Manjón, Wassilios G. Meissner, Thomas Tourdias, Pierrick Coupé
    Journal Name: Brain Communications
    Publisher: Oxford University Press (OUP)
    Vol: 6
    Issue #: 2
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1093/braincomms/fcae055
    Best OA location URL:
    Citation Count: 1
  • Common genetic risk for Parkinson's disease and dysfunction of the endo-lysosomal system
    2024
    OPEN
    Title: Common genetic risk for Parkinson's disease and dysfunction of the endo-lysosomal system
    Author(s): Noopur Bhore, Erin C. Bogacki, Benjamin John O'Callaghan, Hélène Plun‐Favreau, Patrick A. Lewis, Susanne Herbst
    Journal Name: Philosophical Transactions of the Royal Society B: Biological Sciences
    Publisher: The Royal Society
    Vol: 379
    Issue #: 1899
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1098/rstb.2022.0517
    Best OA location URL:
    Citation Count: 2
  • Data‐driven disease progression model of Parkinson's disease and effect of sex and genetic variants
    2024
    OPEN
    Title: Data‐driven disease progression model of Parkinson's disease and effect of sex and genetic variants
    Author(s): Ryota Jin, Hideki Yoshioka, Hiromi Sato, Akihiro Hisaka
    Journal Name: CPT: Pharmacometrics & Systems Pharmacology
    Publisher: Wiley
    Vol: 13
    Issue #: 4
    Start Page: 649
    End Page: 659
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1002/psp4.13112
    Best OA location URL:
    Citation Count: 2
  • Endo-lysosomal dysfunction in neurodegenerative diseases: opinion on current progress and future direction in the use of exosomes as biomarkers
    2024
    RESTRICTED
    Title: Endo-lysosomal dysfunction in neurodegenerative diseases: opinion on current progress and future direction in the use of exosomes as biomarkers
    Author(s): Mathieu Herman, Grace W. Randall, Joan E. Spiegel, D. Maldonado, Sabrina Simoes
    Journal Name: Philosophical Transactions of the Royal Society B: Biological Sciences
    Publisher: The Royal Society
    Vol: 379
    Issue #: 1899
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1098/rstb.2022.0387
    Best OA location URL:
    Citation Count: 3
  • Retromer-dependent lysosomal stress in Parkinson's disease
    2024
    OPEN
    Title: Retromer-dependent lysosomal stress in Parkinson's disease
    Author(s): Dario R. Alessi, Peter J. Cullen, Mark Cookson, Kalpana Merchant, Scott A. Small
    Journal Name: Philosophical Transactions of the Royal Society B: Biological Sciences
    Publisher: The Royal Society
    Vol: 379
    Issue #: 1899
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1098/rstb.2022.0376
    Best OA location URL:
    Citation Count: 2
  • Role of the LRRK2 C-terminal tail in domain crosstalk
    2024
    OPEN
    Title: Role of the LRRK2 C-terminal tail in domain crosstalk
    Author(s): Pallavi Kaila Sharma, Jui-Hung Weng, Jascha T. Manschwetus, Jian Wu, Wen Ma, Friedrich W. Herberg, Susan S. Taylor
    Journal Name: Biochemical Journal
    Publisher: Portland Press Ltd.
    Vol: 481
    Issue #: 4
    Start Page: 313
    End Page: 327
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1042/bcj20230477
    Best OA location URL:
    Citation Count: 0
  • Common mitochondrial deletions in RNA-Seq: evaluation of bulk, single-cell, and spatial transcriptomic datasets
    2024
    OPEN
    Title: Common mitochondrial deletions in RNA-Seq: evaluation of bulk, single-cell, and spatial transcriptomic datasets
    Author(s): Audrey A. Omidsalar, Carmel G. McCullough, Lili Xu, Stanley Boedijono, Daniel S. Gerke, Michelle G. Webb, Zarko Manojlovic, Adolfo Sequeira, Mark Lew, Marco Santorelli, Geidy E. Serrano, Thomas G. Beach, Agenor Limón, Marquis P. Vawter, Brooke E. Hjelm
    Journal Name: Communications Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s42003-024-05877-4
    Best OA location URL:
    Citation Count: 1
  • Levodopa Impairs the Energy Metabolism of the Basal Ganglia In Vivo
    2024
    OPEN
    Title: Levodopa Impairs the Energy Metabolism of the Basal Ganglia In Vivo
    Author(s): Jannik Prasuhn, Tanja Schiefen, Theresia Güber, Julia Henkel, Jan Uter, Julia Steinhardt, Britta Wilms, Norbert Brüggemann
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 95
    Issue #: 5
    Start Page: 849
    End Page: 857
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/ana.26884
    Best OA location URL:
    Citation Count: 3
  • Pathogenetic Contributions and Therapeutic Implications of Transglutaminase 2 in Neurodegenerative Diseases
    2024
    OPEN
    Title: Pathogenetic Contributions and Therapeutic Implications of Transglutaminase 2 in Neurodegenerative Diseases
    Author(s): Jun Liu, M. Maral Mouradian
    Journal Name: International Journal of Molecular Sciences
    Publisher: MDPI AG
    Vol: 25
    Issue #: 4
    Start Page: 2364
    End Page: 2364
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/ijms25042364
    Best OA location URL:
    Citation Count: 1
  • Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease.
    2024
    OPEN
    Title: Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease.
    Author(s): Carlos Cruchaga, Muhammad Ali, Yang-Lin Shen, Anh Do, Lihua Wang, Daniel Western, Menghan Liu, Aleksandra Beric, John Budde, Jen Gentsch, Sabrina Schindler, John C. Morris, David M. Holtzman, María Fernández, Agustín Ruiz, Ignacio Álvarez, Miquel Aguilar, Pau Pástor, Jarod Rutledge, Hamilton Oh, Edward N. Wilson, Yann Le Guen, Rayan Khalid, Chloe Robins, David Pulford, Laura Ibáñez, Tony Wyss‐Coray, Yun Ju Sung
    Journal Name:
    Publisher: Research Square Platform LLC
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.21203/rs.3.rs-3631708/v1
    Best OA location URL:
    Citation Count: 0
  • Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase
    2024
    OPEN
    Title: Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase
    Author(s): Hideyuki Takahashi, Sanaea Bhagwagar, Sarah Helena Nies, Hongping Ye, Xianlin Han, Marius Chiasseu, Guilin Wang, Ian R. Mackenzie, Stephen M. Strittmatter
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 15
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-024-45692-3
    Best OA location URL: https://doi.org/10.1038/s41467-024-45692-3
    Citation Count: 1
  • Deep learning‐based BMI inference from structural brain MRI reflects brain alterations following lifestyle intervention
    2024
    OPEN
    Title: Deep learning‐based BMI inference from structural brain MRI reflects brain alterations following lifestyle intervention
    Author(s): Ofek Finkelstein, Gidon Levakov, Alon Kaplan, Hila Zelicha, Anat Yaskolka Meir, Ehud Rinott, Gal Tsaban, A. Veronica Witte, Matthias Blüher, Michael Stümvoll, Ilan Shelef, Iris Shai, Tammy Riklin Raviv, Galia Avidan
    Journal Name: Human Brain Mapping
    Publisher: Wiley
    Vol: 45
    Issue #: 3
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/hbm.26595
    Best OA location URL:
    Citation Count: 1
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