MJFF Publications

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Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones
2013

OPEN

Title: Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Author(s): Xianming Deng, Jonathan M. Elkins, Jinwei Zhang, Qingkai Yang, Tatiana Erazo, Néstor Gómez, Hwan Geun Choi, Jinhua Wang, Nicolas Dzamko, Jiing-Dwan Lee, Taebo Sim, Namdoo Kim, Dario R. Alessi, José M. Lizcano, Stefan Knapp, Nathanael S. Gray

Journal Name: European Journal of Medicinal Chemistry

Publisher: Elsevier BV

Vol: 70

Issue #:

Start Page: 758

End Page: 767

Publication Date: 2013-10-29

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1016/j.ejmech.2013.10.052

Best OA location URL: https://doi.org/10.1016/j.ejmech.2013.10.052

Citation Count: 46
Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 Diabetes
2013

OPEN

Title: Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 Diabetes

Author(s): Finja Büchel, Florian Mittag, Clemens Wrzodek, Andreas Zell, Thomas Gasser, Manu Sharma

Journal Name: PLoS ONE

Publisher: Public Library of Science (PLoS)

Vol: 8

Issue #: 10

Start Page: e78577

End Page: e78577

Publication Date: 2013-10-25

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1371/journal.pone.0078577

Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0078577&type=printable

Citation Count: 10
Over‐expression of an inactive mutant cathepsin D increases endogenous alpha‐synuclein and cathepsin B activity in SH‐SY5Y cells
2013

OPEN

Title: Over‐expression of an inactive mutant cathepsin D increases endogenous alpha‐synuclein and cathepsin B activity in SH‐SY5Y cells

Author(s): Donna Crabtree, Matthew Dodson, Xiaosen Ouyang, David L. Boone, Qiuli Liang, Mary E. Ballestas, Naomi Fineberg, Jianhua Zhang

Journal Name: Journal of Neurochemistry

Publisher: Wiley

Vol: 128

Issue #: 6

Start Page: 950

End Page: 961

Publication Date: 2013-10-18

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1111/jnc.12497

Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12497

Citation Count: 38
Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutations
2013

OPEN

Title: Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutations

Author(s): Roy N. Alcalay, Anat Mirelman, Rachel Saunders‐Pullman, Ming‐X Tang, Helen Mejia Santana, Deborah Raymond, Ernest Roos, Martha Orbe‐Reilly, Tanya Gurevich, Anat Bar Shira, Mali Gana Weisz, Kira Yasinovsky, Maayan Zalis, Avner Thaler, Andres Deik, Matthew J. Barrett, Jose Cabassa, Mark Groves, Amelia R. Hunt, Naomi Lubarr, Marta San Luciano, Joan Miravite, Christina A. Palmese, Rivka Sachdev, Harini Sarva, Lawrence Severt, Vicki Shanker, Matthew Swan, Jeannie Soto‐Valencia, Brooke Johannes, Robert Ortega, Stanley Fahn, Lucien Côté, Cheryl Waters, Karen Marder, Blair Ford, Elan D. Louis, Oren Levy, Llency Rosado, Diana Ruiz, Tsvyatko Dorovski, Michael W. Pauciulo, William C. Nichols, Avi Orr‐Urtreger, Laurie J. Ozelius, Lorraine N. Clark, Nir Giladi, Susan Bressman, Karen Marder

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 28

Issue #: 14

Start Page: 1966

End Page: 1971

Publication Date: 2013-10-15

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1002/mds.25647

Best OA location URL: https://europepmc.org/articles/pmc3859844?pdf=render

Citation Count: 128
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation
2013

OPEN

Title: The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation

Author(s): Eunju Shin, Carlo Lisci, Elisabetta Tronci, Camino Fidalgo, Roberto Stancampiano, Anders Björklund, Manolo Carta

Journal Name: Neurobiology of Disease

Publisher: Elsevier BV

Vol: 62

Issue #:

Start Page: 233

End Page: 240

Publication Date: 2013-10-15

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.nbd.2013.09.021

Best OA location URL: https://lup.lub.lu.se/search/files/1604585/4934203.pdf

Citation Count: 19
Phosphoproteomic evaluation of pharmacological inhibition of leucine‐rich repeat kinase 2 reveals significant off‐target effects of LRRK‐2‐IN‐1
2013

OPEN

Title: Phosphoproteomic evaluation of pharmacological inhibition of leucine‐rich repeat kinase 2 reveals significant off‐target effects of LRRK‐2‐IN‐1

Author(s): Gregory C. Luerman, Chuong Nguyen, Harry Samaroo, Paula Loos, Hualin Simon Xi, Andres Hurtado‐Lorenzo, Elie Needle, G. Stephen Noell, Paul Galatsis, Y. Bréchet, Kieran F. Geoghegan, Warren D. Hirst

Journal Name: Journal of Neurochemistry

Publisher: Wiley

Vol: 128

Issue #: 4

Start Page: 561

End Page: 576

Publication Date: 2013-10-12

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1111/jnc.12483

Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12483

Citation Count: 60
Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration
2013

OPEN

Title: Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration

Author(s): Naomi Kouri, Yari Carlomagno, Matthew Baker, Amanda M. Liesinger, Richard J. Caselli, Zbigniew K. Wszołek, Leonard Petrucelli, Bradley F. Boeve, Joseph E. Parisi, Keith A. Josephs, Ryan J. Uitti, Owen A. Ross, Neill R. Graff‐Radford, Michael DeTure, Dennis W. Dickson, Rosa Rademakers

Journal Name: Acta Neuropathologica

Publisher: Springer Science and Business Media LLC

Vol: 127

Issue #: 2

Start Page: 271

End Page: 282

Publication Date: 2013-10-11

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1007/s00401-013-1193-7

Best OA location URL: https://europepmc.org/articles/pmc3943649?pdf=render

Citation Count: 72
Herp depletion protects from protein aggregation by up-regulating autophagy
2013

OPEN

Title: Herp depletion protects from protein aggregation by up-regulating autophagy

Author(s): Clara Quiroga, Damián Gatica, Felipe Paredes, Roberto Bravo, Rodrigo Troncoso, Zully Pedrozo, Andrea Rodríguez, Barbra Toro, Mario Chiong, José M. Vicencio, Claudio Hetz, Sergio Lavandero

Journal Name: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Publisher: Elsevier BV

Vol: 1833

Issue #: 12

Start Page: 3295

End Page: 3305

Publication Date: 2013-10-10

Open Access(OA) Status: OPEN

License: publisher-specific-oa

DOI - Digital Object Identifier: 10.1016/j.bbamcr.2013.09.006

Best OA location URL: https://doi.org/10.1016/j.bbamcr.2013.09.006

Citation Count: 36
Tardive Dyskinesia: Therapeutic Options for an Increasingly Common Disorder
2013

OPEN

Title: Tardive Dyskinesia: Therapeutic Options for an Increasingly Common Disorder

Author(s): Leslie J. Cloud, Deepti Zutshi, Stewart A. Factor

Journal Name: Neurotherapeutics

Publisher: Elsevier BV

Vol: 11

Issue #: 1

Start Page: 166

End Page: 176

Publication Date: 2013-10-10

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1007/s13311-013-0222-5

Best OA location URL: https://europepmc.org/articles/pmc3899488?pdf=render

Citation Count: 101
Dopamine overdose hypothesis: Evidence and clinical implications
2013

RESTRICTED

Title: Dopamine overdose hypothesis: Evidence and clinical implications

Author(s): David E. Vaillancourt, Daniel Schonfeld, Youngbin Kwak, Nicolaas I. Bohnen, Rachael D. Seidler

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 28

Issue #: 14

Start Page: 1920

End Page: 1929

Publication Date: 2013-10-09

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1002/mds.25687

Best OA location URL: https://europepmc.org/articles/pmc3859825?pdf=render

Citation Count: 135
The regulation and deregulation of Wnt signaling by PARK genes in health and disease
2013

RESTRICTED

Title: The regulation and deregulation of Wnt signaling by PARK genes in health and disease

Author(s): Daniel C. Berwick, Kate Harvey

Journal Name: Journal of Molecular Cell Biology

Publisher: Oxford University Press (OUP)

Vol: 6

Issue #: 1

Start Page: 3

End Page: 12

Publication Date: 2013-10-09

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1093/jmcb/mjt037

Best OA location URL: https://academic.oup.com/jmcb/article-pdf/6/1/3/2590207/mjt037.pdf

Citation Count: 63
Pooled analysis of iron-related genes in Parkinson's disease: Association with transferrin
2013

OPEN

Title: Pooled analysis of iron-related genes in Parkinson's disease: Association with transferrin

Author(s): Shannon Rhodes, Daniel D. Buchanan, Ismaïl Ahmed, Kent D. Taylor, Marie‐Anne Loriot, Janet S. Sinsheimer, Jeff M. Bronstein, Alexis Elbaz, George D. Mellick, Jerome I. Rotter, Beate Ritz

Journal Name: Neurobiology of Disease

Publisher: Elsevier BV

Vol: 62

Issue #:

Start Page: 172

End Page: 178

Publication Date: 2013-10-08

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.nbd.2013.09.019

Best OA location URL: https://europepmc.org/articles/pmc3968945?pdf=render

Citation Count: 76
Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers
2013

RESTRICTED

Title: Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers

Author(s): Li Shen, Paul M. Thompson, Steven G. Potkin, Lars Bertram, Lindsay A. Farrer, Tatiana Foroud, Robert Green, Xiaolan Hu, Matthew J. Huentelman, Sungeun Kim, John Kauwe, Qingqin S. Li, Enchi Liu, Fabìo Macciardi, Jason H. Moore, Leanne Munsie, Kwangsik Nho, Vijay K. Ramanan, Shannon L. Risacher, David J. Stone, Shanker Swaminathan, Arthur W. Toga, Michael W. Weiner, Andrew J. Saykin

Journal Name: Brain Imaging and Behavior

Publisher: Springer Science and Business Media LLC

Vol: 8

Issue #: 2

Start Page: 183

End Page: 207

Publication Date: 2013-10-05

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1007/s11682-013-9262-z

Best OA location URL: https://link.springer.com/content/pdf/10.1007/s11682-013-9262-z.pdf

Citation Count: 148
Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway
2013

OPEN

Title: Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway

Author(s): Keiichi Inoue, Joanne Rispoli, Lichuan Yang, David MacLeod, M. Flint Beal, Eric Klann, Asa Abeliovich

Journal Name: PLoS Genetics

Publisher: Public Library of Science (PLoS)

Vol: 9

Issue #: 10

Start Page: e1003845

End Page: e1003845

Publication Date: 2013-10-03

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1371/journal.pgen.1003845

Best OA location URL: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003845&type=printable

Citation Count: 18
Epigenetic Landscape of Parkinson’s Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities
2013

RESTRICTED

Title: Epigenetic Landscape of Parkinson’s Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities

Author(s): Navneet Ammal Kaidery, Shaista Tarannum, Bobby Thomas

Journal Name: Neurotherapeutics

Publisher: Elsevier BV

Vol: 10

Issue #: 4

Start Page: 698

End Page: 708

Publication Date: 2013-10-01

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1007/s13311-013-0211-8

Best OA location URL: https://europepmc.org/articles/pmc3805874?pdf=render

Citation Count: 73
Neural correlates of executive functions in healthy G2019S LRRK2 mutation carriers
2013

RESTRICTED

Title: Neural correlates of executive functions in healthy G2019S LRRK2 mutation carriers

Author(s): Avner Thaler, Anat Mirelman, Rick C. Helmich, Bart F.L. van Nuenen, Keren Rosenberg‐Katz, Tanya Gurevich, Avi Orr‐Urtreger, Karen Marder, Susan Bressman, Bastiaan R. Bloem, Nir Giladi, Talma Hendler

Journal Name: Cortex

Publisher: Elsevier BV

Vol: 49

Issue #: 9

Start Page: 2501

End Page: 2511

Publication Date: 2013-10-01

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1016/j.cortex.2012.12.017

Best OA location URL:

Citation Count: 44
Crawling of effector T cells on extracellular matrix: role of integrins in interstitial migration in inflamed tissues
2013

OPEN

Title: Crawling of effector T cells on extracellular matrix: role of integrins in interstitial migration in inflamed tissues

Author(s): Chang H. Kim

Journal Name: Cellular & Molecular Immunology

Publisher: Springer Science and Business Media LLC

Vol: 11

Issue #: 1

Start Page: 1

End Page: 4

Publication Date: 2013-09-23

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1038/cmi.2013.47

Best OA location URL: https://europepmc.org/articles/pmc4002148?pdf=render

Citation Count: 12
Effects of prolonged selective serotonin reuptake inhibition on the development and expression of l-DOPA-induced dyskinesia in hemi-parkinsonian rats
2013

OPEN

Title: Effects of prolonged selective serotonin reuptake inhibition on the development and expression of l-DOPA-induced dyskinesia in hemi-parkinsonian rats

Author(s): Melissa M. Conti, Corinne Y. Ostock, David Lindenbach, Adam A. Goldenberg, Elias Kampton, Rich Dell'isola, Aaron Katzman, Christopher Bishop

Journal Name: Neuropharmacology

Publisher: Elsevier BV

Vol: 77

Issue #:

Start Page: 1

End Page: 8

Publication Date: 2013-09-22

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.neuropharm.2013.09.017

Best OA location URL: https://europepmc.org/articles/pmc3865178?pdf=render

Citation Count: 61
Autonomic complaints in patients with restless legs syndrome
2013

OPEN

Title: Autonomic complaints in patients with restless legs syndrome

Author(s): Natalya Shneyder, Charles H. Adler, Joseph G. Hentz, Holly A. Shill, John N. Caviness, Marwan N. Sabbagh, Thomas G. Beach, Erika Driver‐Dunckley

Journal Name: Sleep Medicine

Publisher: Elsevier BV

Vol: 14

Issue #: 12

Start Page: 1413

End Page: 1416

Publication Date: 2013-09-21

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.sleep.2013.08.781

Best OA location URL: https://europepmc.org/articles/pmc4105217?pdf=render

Citation Count: 31
Thalamic cholinergic innervation and postural sensory integration function in Parkinson’s disease
2013

OPEN

Title: Thalamic cholinergic innervation and postural sensory integration function in Parkinson’s disease

Author(s): Martijn L.T.M. Müller, Roger L. Albin, Vikas Kotagal, Robert A. Koeppe, Peter J. H. Scott, Kirk A. Frey, Nicolaas I. Bohnen

Journal Name: Brain

Publisher: Oxford University Press (OUP)

Vol: 136

Issue #: 11

Start Page: 3282

End Page: 3289

Publication Date: 2013-09-20

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1093/brain/awt247

Best OA location URL: https://academic.oup.com/brain/article-pdf/136/11/3282/11138755/awt247.pdf

Citation Count: 155
Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive Phosphate
2013

OPEN

Title: Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive Phosphate

Author(s): Jean‐Marc Taymans, Fangye Gao, Veerle Baekelandt

Journal Name: Journal of Visualized Experiments

Publisher: MyJove Corporation

Vol:

Issue #: 79

Start Page:

End Page:

Publication Date: 2013-09-18

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.3791/50523

Best OA location URL: https://europepmc.org/articles/pmc3923590?pdf=render

Citation Count: 4
Metabolomics and the search for biomarkers in Parkinson's disease
2013

OPEN

Title: Metabolomics and the search for biomarkers in Parkinson's disease

Author(s): Amy W. Amara, David G. Standaert

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 28

Issue #: 12

Start Page: 1620

End Page: 1621

Publication Date: 2013-09-18

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1002/mds.25644

Best OA location URL: https://europepmc.org/articles/pmc4050667?pdf=render

Citation Count: 9
The Evolving Role of Diffusion Magnetic Resonance Imaging in Movement Disorders
2013

RESTRICTED

Title: The Evolving Role of Diffusion Magnetic Resonance Imaging in Movement Disorders

Author(s): Christopher W. Hess, Edward Ofori, Umer Akbar, Michael S. Okun, David E. Vaillancourt

Journal Name: Current Neurology and Neuroscience Reports

Publisher: Springer Science and Business Media LLC

Vol: 13

Issue #: 11

Start Page:

End Page:

Publication Date: 2013-09-18

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1007/s11910-013-0400-1

Best OA location URL: https://europepmc.org/articles/pmc3824956?pdf=render

Citation Count: 12
Imaging: What can it tell us about parkinsonian gait?
2013

RESTRICTED

Title: Imaging: What can it tell us about parkinsonian gait?

Author(s): Nicolaas I. Bohnen, Klaus Jahn

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 28

Issue #: 11

Start Page: 1492

End Page: 1500

Publication Date: 2013-09-15

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1002/mds.25534

Best OA location URL: https://europepmc.org/articles/pmc3801220?pdf=render

Citation Count: 76
Cheek cell–derived α-synuclein and DJ-1 do not differentiate Parkinson's disease from control
2013

OPEN

Title: Cheek cell–derived α-synuclein and DJ-1 do not differentiate Parkinson's disease from control

Author(s): Tessandra Stewart, Yu-Ting Sui, Luis F. Gonzalez‐Cuyar, David T. Wong, David Akin, Vítor Tumas, Jan Aasly, Emily Ashmore, Patrick Aro, Carmen Ginghină, Ané Korff, Cyrus P. Zabetian, James B. Leverenz, Min Shi, Jing Zhang

Journal Name: Neurobiology of Aging

Publisher: Elsevier BV

Vol: 35

Issue #: 2

Start Page: 418

End Page: 420

Publication Date: 2013-09-13

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.08.008

Best OA location URL: https://escholarship.org/content/qt8m97s2kf/qt8m97s2kf.pdf?t=rsqp1s

Citation Count: 30

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