The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biomarkers, 2025Dried Blood Spot PNPO Activity as a Biomarker for the Stratification of Parkinson's Disease
Study Rationale: Parkinson’s disease starts much earlier than the signs appear and people seek diagnosis. Scientists are therefore searching for changes that are relevant to the disease that could be...
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Neuronal Synuclein Disease Endotypes 2024, 2025Expanding Biomarker Characterization in Deeply Phenotyped DLB, PD and PDD Cohorts
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Research Grant, 2025Scamps: Endosomal Membrane Proteins that Control Alpha-synuclein Traffic
Study Rationale: Parkinson’s Disease progresses with the death of nerve cells in the brain. Some forms of the disease run in families due to mutations in important genes. One of these genes is called...
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Research Grant, 2025Analysis of 18F-DPA714 Dynamic Data with Arterial Sampling Obtained at UAB
Study Rationale: The study will analyze clinical PET data from 5 subjects imaged dynamically with 18F-DPA714, an imaging larker for brain inflammation. The purpose of the study is to ensure that...
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Research Grant, 2025Analysis of a Potential Alpha-synuclein PET Tracer (18F-FD4) in HC, PD and MSA
Study Rationale: 18F-FD4 is a new imaging agent that has the potential to image alpha-synuclein in the living human brain with Positron Emission Tomography (PET). Given alpha-synuclein’s central role...
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Circuits & Cellular Targets for PD’s Symptoms, 2025Role of B2*-Nicotinic Receptors in Parkinson’s Disease Related Circuits and Symptoms
Study Rationale: One pathological hallmark of Parkinson’s disease (PD) is the degeneration of dopamine neurons innervating the striatum. Dopamine loss is associated with several adaptive changes in...
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Our funding programs support basic, translational and clinical research from academia and industry.