The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Cell Line, 2002Dopamine Neurons Derived from Human ES Cells
Embryonic stem (ES) cells proliferate extensively, and preliminary data show that animal ES cells can be manipulated to generate highly enriched populations of dopamine neurons that express genes...
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Cell Line, 2002Unlimited Numbers of Purified Midbrain Dopamine Neurons from Human Embryonic Stem Cells
The fact that dopamine (DA) cells are lost specifically but other nerve cells are still intact makes Parkinson's disease (PD) uniquely amenable to cell replacement therapy. Early attempts have...
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Cell Line, 2002Banking of and Dopamine Neuronal Production from Human Neural Stem Cells
Transplantation of dopamine neurons in Parkinson's disease has resulted in significant improvements for some patients. However, large-scale clinical trials are impossible due to the technical and...
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Cell Line, 2002Generation of Transplantable Dopamine Neurons from Human Emryonic Stem Cells
The focal nature of neuronal loss suggests that cell replacement therapy may be suitable for Parkinson's disease. Indeed, transplanted fetal midbrain cells survive in some Parkinson's patients for...
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Fast Track, 2001Lentiviral Delivery of Neublastin to MPTP-Treated Pre-clinical models
Parkinson's disease (PD) results primarily from striatal dopamine (DA) insufficiency and degeneration of dopaminergic neurons within the substantia nigra pars compacta. The cause of PD still remains...
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Fast Track, 2001Rapid Parkinson's Drug Screen Using Parkin Knockout Stem Cells
Autosomal recessive loss-of-function mutations in the parkin gene are the most common cause of familial Parkinson's disease (PD), which is characterized by selective loss of dopaminergic (DA) neurons...
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Our funding programs support basic, translational and clinical research from academia and industry.