To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
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* = MJFF does not control pricing or terms of availability for this tool.
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Rab 8A ELISA*
Assay
ELISA kit designed for the quantitative measurement of Rab8A protein in human cell and tissue extract samples.
Rab 10 ELISA*
Assay
ELISA kit designed for the quantitative measurement of Rab10 protein in human, mouse and rat cell and tissue extract samples.
pT73 Rab 10 Protein
Protein
Phospho-T73 Rab10 synthetic phosphomimetic protein fragment (AA66-181) generated by native chemical ligation of recombinant peptides. This protein was designed and generated by X'PROCHEM.
PPMI iPSCs
Human iPS Cell
Induced pluripotent stem cell (iPSC) lines are available through the PPMI repository. The repository includes lines from control, idiopathic PD, genetic PD (LRRK2, GBA, SNCA), genetic unaffected carriers (LRRK2, LRRK2/GBA, GBA, SNCA), and prodromal patients. Gene-revertant controls are available for select lines. An inventory of available lines can be found here: https://zenodo.org/records/10783308
Total Rab 29 Antibody (Hu/Ms)
Antibody
Rabbit monoclonal antibody directed against the human and mouse total Rab 29 protein. Suitable for immunoblot and immunoprecipitation experiments. This antibody epitope was mapped to amino acids 148-153.
Total Rab 8 Antibody (Hu)
Antibody
Rabbit monoclonal antibody directed against the human total Rab 8 protein. Suitable for immunoblot, immunostaining, flow cytometry, and immunoprecipitation experiments. Epitope was mapped to amino acids 189-199.
LRRK2 Antibody (UDD3)
Antibody
Rabbit monoclonal antibody directed against the N-terminus (LRRK2(100-500)) of wild-type LRRK2. This antibody has been found to be superior in immunoprecipitation of LRRK2 from a variety of cell lysates and tissues.
Rab 7A pS72 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 72 of the human Rab7A protein. Suitable for immunoblot and immunohistochemical experiments.
Rab 29 pS72 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 72 of the human Rab29 protein. Suitable for immunoblot applications.
Parkin KO Rat*
Rat Model
Homozygous rat knockout of Parkin in the Long Evans Hooded rat strain. RRID:RGD_7241052
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"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic