To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Rab8 pS111 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine111 of the human Rab8 protein (PINK1-related phosphorylation event). Suitable for immunoblot and immunocytochemistry experiments.
AAV2/5-CBh-eBFP
Viral Vector
Viral Vector (AAV2/5 serotype) encoding eBFP to be used as a control for the AAv2/5 WT Human alpha-synuclein viral vector. This virus will not be made available as the QC/QA testing shows that it induces undesired inflammation and toxicity. Since stocks are available, groups may send a request for samples to tools@michaeljfox.org and may be granted access after vetting.
LRRK2 Antibody (N241A/34)
Antibody
Mouse monoclonal antibody directed against wild-type LRRK2 using a fragment of LRRK2 (AA 970-2527).
Rab 8 pT72 Phosphospecific Antibody (Non-Selective)
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine72 of the human Rab 8 protein. Suitable for immunoblot and immunoprecipitation experiments. Note: Cross reacts with threonine-phosphorylated Rabs 3, 10, 35, and 43.
Rab 10 pT73 Phosphospecific Antibody (IP/WB)
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine73 of the Rab 10 protein. Recommended for immunoblot and immunoprecipitation. A separate antibody (ab241060) is available for immunostaining.
Rab 29 pT71 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine71 of the human Rab 29 protein. Suitable for immunoblot experiments.
Total Rab 10 Antibody
Antibody
Rabbit monoclonal antibody directed against the total Rab 10 protein. Suitable for immunoblot, immunoprecipitation, immunofluorescent staining, and flow cytometry experiments. This antibody epitope was mapped to C-terminus amino acids 185-193.
Ubiquitin pS65 Phosphospecific Antibody (WB/ICC/ELISA)
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine65 of ubiquitin. Suitable for immunoblot, immunocytochemistry, and ELISA applications. Detailed characterization data is published in Watzlawik et al, Autophagy 2024.
Total DJ-1 Antibody
Antibody
Mouse monoclonal antibody directed against full length DJ-1. Ideal for use in immunoblotting or immunoassays.
LRRK2 G2019S KI Mouse
Mouse Model
Mice expressing the human G2019S point mutation introduced into exon 41 of the mouse LRRK2 gene.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic