651 - 675 of 6420 Results
Title
Year
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OPENTitle: Solution-Phase Parallel Synthesis and SAR of Homopiperazinyl Analogs as Positive Allosteric Modulators of mGlu4Journal Name: ACS Combinatorial SciencePublisher: American Chemical Society (ACS)Vol: 13Issue #: 2Start Page: 159End Page: 165Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/co1000508Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3057427Citation Count: 8
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OPENTitle: Allopregnanolone Reinstates Tyrosine Hydroxylase Immunoreactive Neurons and Motor Performance in an MPTP-Lesioned Mouse Model of Parkinson's DiseaseJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 11Start Page: e50040End Page: e50040Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0050040Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0050040&type=printableCitation Count: 50
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OPENTitle: Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Journal Name: Cellular and Molecular Life SciencesPublisher: Springer Science and Business Media LLCVol: 69Issue #: 20Start Page: 3511End Page: 3527Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1007/s00018-012-1071-9Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00018-012-1071-9.pdfCitation Count: 33
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OPENTitle: Remote control of induced dopaminergic neurons in parkinsonian ratsJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 124Issue #: 7Start Page: 3215End Page: 3229Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci74664Best OA location URL: http://www.jci.org/articles/view/74664/files/pdfCitation Count: 118
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OPENTitle: Binding of the Radioligand SIL23 to α-Synuclein Fibrils in Parkinson Disease Brain Tissue Establishes Feasibility and Screening Approaches for Developing a Parkinson Disease Imaging AgentJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 2Start Page: e55031End Page: e55031Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0055031Best OA location URL: https://doi.org/10.1371/journal.pone.0055031Citation Count: 116
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OPENTitle: Inhibitor treatment of peripheral mononuclear cells from Parkinson’s disease patients further validates LRRK2 dephosphorylation as a pharmacodynamic biomarkerJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep31391Best OA location URL: https://www.nature.com/articles/srep31391.pdfCitation Count: 260
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OPENTitle: Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2Journal Name: Nature Chemical BiologyPublisher: Springer Science and Business Media LLCVol: 7Issue #: 4Start Page: 203End Page: 205Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nchembio.538Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3287420Citation Count: 421
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OPENTitle: A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptorsJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 1Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ncomms1085Best OA location URL: https://www.nature.com/articles/ncomms1085.pdfCitation Count: 151
- Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging2016OPENTitle: Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of AgingJournal Name: Journal of the American Geriatrics SocietyPublisher: WileyVol: 65Issue #: 4Start Page: 792End Page: 799Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/jgs.14670Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5397339Citation Count: 56
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OPENTitle: LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site statusJournal Name: Frontiers in Molecular NeurosciencePublisher: Frontiers Media SAVol: 7Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnmol.2014.00054Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2014.00054/pdfCitation Count: 69
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OPENTitle: Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs)Journal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 52Issue #: 14Start Page: 4115End Page: 4118Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm9005065Best OA location URL: http://doi.org/10.1021/jm9005065Citation Count: 80
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OPENTitle: The Association Between Plasma Ceramides and Sphingomyelins and Risk of Alzheimer’s Disease Differs by Sex and APOE in the Baltimore Longitudinal Study of AgingJournal Name: Journal of Alzheimer's DiseasePublisher: SAGE PublicationsVol: 60Issue #: 3Start Page: 819End Page: 828Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jad-160925Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5493514Citation Count: 68
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OPENTitle: LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contextsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep29945Best OA location URL: https://www.nature.com/articles/srep29945.pdfCitation Count: 129
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OPENTitle: Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicityJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 22Issue #: 2Start Page: 328End Page: 344Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/dds431Best OA location URL: https://academic.oup.com/hmg/article-pdf/22/2/328/1857445/dds431.pdfCitation Count: 76
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OPENTitle: The association between Mediterranean diet adherence and Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 27Issue #: 6Start Page: 771End Page: 774Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.24918Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3349773Citation Count: 206
- Objective Assessment of Fall Risk in Parkinson's Disease Using a Body-Fixed Sensor Worn for 3 Days2014OPENTitle: Objective Assessment of Fall Risk in Parkinson's Disease Using a Body-Fixed Sensor Worn for 3 DaysJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 5Start Page: e96675End Page: e96675Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0096675Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096675&type=printableCitation Count: 214
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OPENTitle: Striatal Overexpression of ΔJunD Resets L-DOPA-Induced Dyskinesia in a Primate Model of Parkinson DiseaseJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 66Issue #: 6Start Page: 554End Page: 561Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2009.04.005Best OA location URL: http://doi.org/10.1016/j.biopsych.2009.04.005Citation Count: 91
- PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies2015OPENTitle: PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy BodiesJournal Name: Neurodegenerative DiseasesPublisher: S. Karger AGVol: 16Issue #: 1-2Start Page: 118End Page: 124Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1159/000441421Best OA location URL: https://karger.com/ndd/article-pdf/16/1-2/118/3135738/000441421.pdfCitation Count: 50
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OPENTitle: Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulatorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 21Issue #: 23Start Page: 6955End Page: 6959Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2011.09.131Citation Count: 18
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OPENTitle: Gait impairment precedes clinical symptoms in spinocerebellar ataxia type 6Journal Name: Movement DisordersPublisher: WileyVol: 29Issue #: 2Start Page: 252End Page: 255Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25706Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6551218Citation Count: 64
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OPENTitle: Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutationsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 109Issue #: 26Start Page: 10322End Page: 10327Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1203223109Best OA location URL: https://www.pnas.org/content/pnas/109/26/10322.full.pdfCitation Count: 97
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OPENTitle: Detraining outcomes with expiratory muscle strength training in Parkinson diseaseJournal Name: Journal of Rehabilitation Research and DevelopmentPublisher: Journal of Rehabilitation Research & DevelopmentVol: 51Issue #: 2Start Page: 305End Page: 310Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1682/jrrd.2013.05.0101Best OA location URL: http://doi.org/10.1682/JRRD.2013.05.0101Citation Count: 52
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OPENTitle: Evaluation of D2 and D3 dopamine receptor selective compounds on l-dopa-dependent abnormal involuntary movements in ratsJournal Name: NeuropharmacologyPublisher: Elsevier BVVol: 56Issue #: 6-7Start Page: 956End Page: 969Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuropharm.2009.01.019Best OA location URL: http://doi.org/10.1016/j.neuropharm.2009.01.019Citation Count: 53
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OPENTitle: Whole-Exome Sequencing in Familial Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 73Issue #: 1Start Page: 68End Page: 68Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2015.3266Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2470417/noi150080.pdfCitation Count: 75
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OPENTitle: Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson’s disease subjectsJournal Name: Neurological ResearchPublisher: Informa UK LimitedVol: 34Issue #: 7Start Page: 669End Page: 676Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1179/1743132812y.0000000063Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3681206Citation Count: 65