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1126 - 1150 of 6420 Results
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  • Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease
    2009
    Summary Details
    OPEN
    Title: Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease
    Author(s): Juliane Neumann, José Brás, Emma Deas, Sean S. O’Sullivan, Laura Parkkinen, Robin Lachmann, Abi Li, Janice L. Holton, Rita Guerreiro, Reema Paudel, Badmavady Segarane, Andrew Singleton, Andrew J. Lees, John Hardy, Henry Houlden, Tamás Révész, Nicholas Wood
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 132
    Issue #: 7
    Start Page: 1783
    End Page: 1794
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/brain/awp044
    Best OA location URL: https://academic.oup.com/brain/article-pdf/132/7/1783/13734818/awp044.pdf
    Citation Count: 668
  • Measuring mild cognitive impairment in patients with Parkinson's disease
    2013
    Summary Details
    OPEN
    Title: Measuring mild cognitive impairment in patients with Parkinson's disease
    Author(s): Connie Marras, Melissa J. Armstrong, Christopher Meaney, Susan H. Fox, Brandon Rothberg, William Reginold, David F. Tang‐Wai, David Gill, Paul J. Eslinger, Cindy Zadikoff, Nancy Kennedy, Fred Marshall, Mark Mapstone, Kelvin L. Chou, Carol Persad, Irene Litvan, Benjamin T. Mast, Adam Gerstenecker, Sandra Weıntraub, Sarah Duff‐Canning
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 28
    Issue #: 5
    Start Page: 626
    End Page: 633
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25426
    Best OA location URL: https://hdl.handle.net/2027.42/98243
    Citation Count: 134
  • Variant ataxia-telangiectasia presenting as primary-appearing dystonia in Canadian Mennonites
    2012
    Summary Details
    OPEN
    Title: Variant ataxia-telangiectasia presenting as primary-appearing dystonia in Canadian Mennonites
    Author(s): Rachel Saunders‐Pullman, Deborah Raymond, A. Jon Stoessl, Douglas E. Hobson, Toshitaka Nakamura, Seth L. Pullman, D Lefton, Michael S. Okun, Ryan J. Uitti, Rivka Sachdev, Kaili Stanley, Marta San Luciano, J. Hagenah, Richard A. Gatti, Laurie J. Ozelius, Susan Bressman
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 78
    Issue #: 9
    Start Page: 649
    End Page: 657
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e3182494d51
    Best OA location URL: https://n.neurology.org/content/neurology/78/9/649.full.pdf
    Citation Count: 90
  • Attentional resource allocation and swallowing safety in Parkinson's disease: A dual task study
    2014
    Summary Details
    OPEN
    Title: Attentional resource allocation and swallowing safety in Parkinson's disease: A dual task study
    Author(s): Michelle S. Troche, Michael S. Okun, John C. Rosenbek, Lori J. P. Altmann, Christine M. Sapienza
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 20
    Issue #: 4
    Start Page: 439
    End Page: 443
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2013.12.011
    Best OA location URL: http://doi.org/10.1016/j.parkreldis.2013.12.011
    Citation Count: 45
  • Interest in Genetic Testing in Ashkenazi Jewish Parkinson's Disease Patients and Their Unaffected Relatives
    2014
    Summary Details
    OPEN
    Title: Interest in Genetic Testing in Ashkenazi Jewish Parkinson's Disease Patients and Their Unaffected Relatives
    Author(s): Manisha Gupte, Roy N. Alcalay, Helen Mejia‐Santana, Deborah Raymond, Rachel Saunders‐Pullman, Ernest Roos, Martha Orbe‐Reily, Ming‐X Tang, Anat Mirelman, Laurie J. Ozelius, Avi Orr‐Urtreger, Lorraine N. Clark, Nir Giladi, Susan Bressman, Karen Marder
    Journal Name: Journal of Genetic Counseling
    Publisher: Wiley
    Vol: 24
    Issue #: 2
    Start Page: 238
    End Page: 246
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s10897-014-9756-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4331260
    Citation Count: 29
  • Treatment With Cholinesterase Inhibitors and Memantine of Patients in the Alzheimer's Disease Neuroimaging Initiative
    2011
    Summary Details
    OPEN
    Title: Treatment With Cholinesterase Inhibitors and Memantine of Patients in the Alzheimer's Disease Neuroimaging Initiative
    Author(s): Lon S. Schneider, Philip S. Insel, Michael W. Weiner
    Journal Name: Archives of Neurology
    Publisher: American Medical Association (AMA)
    Vol: 68
    Issue #: 1
    Start Page: 58
    End Page: 58
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/archneurol.2010.343
    Citation Count: 151
  • A randomized, double-blind study of repeated incobotulinumtoxinA (Xeomin®) in cervical dystonia
    2013
    Summary Details
    OPEN
    Title: A randomized, double-blind study of repeated incobotulinumtoxinA (Xeomin®) in cervical dystonia
    Author(s): Virgilio Gerald H. Evidente, Hubert H. Fernandez, Mark S. LeDoux, Allison Brashear, Susanne Grafe, Angelika Hanschmann, Cynthia Comella
    Journal Name: Journal of Neural Transmission
    Publisher: Springer Science and Business Media LLC
    Vol: 120
    Issue #: 12
    Start Page: 1699
    End Page: 1707
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00702-013-1048-3
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00702-013-1048-3.pdf
    Citation Count: 66
  • LRRK2 secretion in exosomes is regulated by 14-3-3
    2013
    Summary Details
    OPEN
    Title: LRRK2 secretion in exosomes is regulated by 14-3-3
    Author(s): K. B. Fraser, Mark S. Moehle, João Paulo Lima Daher, P. J. Webber, J. Y. Williams, Charles A. Stewart, Talene A. Yacoubian, Rita M. Cowell, Terje Dokland, Tong Ye, Daxin Chen, Gene P. Siegal, Robert A. Galemmo, Elpida Tsika, Darren J. Moore, David G. Standaert, Kensuke Kojima, James A. Mobley, Andrew B. West
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Vol: 22
    Issue #: 24
    Start Page: 4988
    End Page: 5000
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddt346
    Best OA location URL: https://academic.oup.com/hmg/article-pdf/22/24/4988/14140078/ddt346.pdf
    Citation Count: 161
  • O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease
    2015
    Summary Details
    OPEN
    Title: O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease
    Author(s): Nicholas P. Marotta, Yu Lin, Yuka E. Lewis, Mark R. Ambroso, Balyn W. Zaro, Maxwell T. Roth, Don B. Arnold, Ralf Langen, Matthew R. Pratt
    Journal Name: Nature Chemistry
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 11
    Start Page: 913
    End Page: 920
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nchem.2361
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4618406
    Citation Count: 253
  • Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
    2008
    Summary Details
    OPEN
    Title: Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
    Author(s): Liyan Qiao, Shusei Hamamichi, Kim A. Caldwell, Guy A. Caldwell, Talene A. Yacoubian, Scott M. Wilson, Zuolei Xie, Lisa D Speake, Rachael Parks, Donna Crabtree, Qiuli Liang, Stephen Crimmins, Lonnie Schneider, Yasuo Uchiyama, Takeshi Iwatsubo, Yi Zhou, Lisheng Peng, Youming Lu, David G. Standaert, Ken C. Walls, John J. Shacka, Kevin A. Roth, Jianhua Zhang
    Journal Name: Molecular Brain
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/1756-6606-1-17
    Best OA location URL: https://molecularbrain.biomedcentral.com/counter/pdf/10.1186/1756-6606-1-17
    Citation Count: 244
  • Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
    2009
    Summary Details
    OPEN
    Title: Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
    Author(s): Hui Xiong, Danling Wang, Linan Chen, Yeun Su Choo, Hong Ma, Chengyuan Tang, Kun Xia, Wei Jiang, Ze’ev A. Ronai, Xiaoxi Zhuang, Zhuohua Zhang
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Vol: 119
    Issue #: 3
    Start Page: 650
    End Page: 660
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1172/jci37617
    Best OA location URL: http://doi.org/10.1172/JCI37617
    Citation Count: 376
  • Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease
    2007
    Summary Details
    OPEN
    Title: Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease
    Author(s): Anamitra Ghosh, Avik Roy, Xiaojuan Liu, Jeffrey H. Kordower, Elliott J. Mufson, Dean M. Hartley, Sankar Ghosh, R. Lee Mosley, Howard E. Gendelman, Kalipada Pahan
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 104
    Issue #: 47
    Start Page: 18754
    End Page: 18759
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0704908104
    Best OA location URL: http://doi.org/10.1073/pnas.0704908104
    Citation Count: 416
  • Integrated molecular landscape of Parkinson’s disease
    2017
    Summary Details
    OPEN
    Title: Integrated molecular landscape of Parkinson’s disease
    Author(s): Cornelius J. H. M. Klemann, Gerard J.M. Martens, Manu Sharma, Marijn B. Martens, Ole Isacson, Thomas Gasser, Jasper E. Visser, Geert Poelmans
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-017-0015-3
    Best OA location URL: https://pub.dzne.de/search?p=id:%22DZNE-2020-01126%22
    Citation Count: 118
  • Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasis
    2016
    Summary Details
    OPEN
    Title: Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasis
    Author(s): Gaia Skibinski, Vicky Hwang, D. Michael Ando, Aaron Daub, Alicia K. Lee, Abinaya Ravisankar, Sara Modan, Mariel M. Finucane, Benjamin A. Shaby, Steven Finkbeiner
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 114
    Issue #: 5
    Start Page: 1165
    End Page: 1170
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1522872114
    Best OA location URL: https://www.pnas.org/content/pnas/114/5/1165.full.pdf
    Citation Count: 115
  • LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease
    2010
    Summary Details
    OPEN
    Title: LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease
    Author(s): Chen Yao, Rabih El Khoury, Wen Wang, Tara A. Byrd, Elizabeth A. Pehek, Colin Thacker, Xiongwei Zhu, Mark A. Smith, Amy L. Wilson‐Delfosse, Shu G. Chen
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 40
    Issue #: 1
    Start Page: 73
    End Page: 81
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.04.002
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2926296
    Citation Count: 143
  • Involvement of Perineuronal and Perisynaptic Extracellular Matrix in Alzheimer's Disease Neuropathology
    2011
    Summary Details
    OPEN
    Title: Involvement of Perineuronal and Perisynaptic Extracellular Matrix in Alzheimer's Disease Neuropathology
    Author(s): Markus Morawski, Gert Brückner, Carsten Jäger, Gudrun Seeger, Russel T. Matthews, Thomas Arendt
    Journal Name: Brain Pathology
    Publisher: Wiley
    Vol: 22
    Issue #: 4
    Start Page: 547
    End Page: 561
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/j.1750-3639.2011.00557.x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3639011
    Citation Count: 146
  • Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells
    2007
    Summary Details
    OPEN
    Title: Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells
    Author(s): D. Eugene Redmond, Kimberly B. Bjugstad, Yang D. Teng, Václav Ourednik, Jitka Ourednik, Dustin R. Wakeman, Xuejun H. Parsons, Rodolfo Gonzalez, B. C. Blanchard, Seung Up Kim, Zezong Gu, Stuart A. Lipton, Eleni A. Markakis, Robert H. Roth, John D. Elsworth, John R. Sladek, Richard L. Sidman, Evan Y. Snyder
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 104
    Issue #: 29
    Start Page: 12175
    End Page: 12180
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0704091104
    Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0704091104
    Citation Count: 347
  • Loss-of-function mutations in theATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)
    2016
    Summary Details
    OPEN
    Title: Loss-of-function mutations in theATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)
    Author(s): Alejandro Estrada‐Cuzcano, Shaun Martin, Teodora Chamova, Matthis Synofzik, Dagmar Timmann, Tine Holemans, Albena Andreeva, Jennifer Reichbauer, Riet De Rycke, Dae-In Chang, Sarah van Veen, J. Pon Samuel, Lüdger Schöls, Thorsten Pöppel, Danny Mollerup Sørensen, Bob Asselbergh, Christine Klein, Stephan Züchner, Albena Jordanova, Peter Vangheluwe, Ivailo Tournev, Rebecca Schüle
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 140
    Issue #: 2
    Start Page: 287
    End Page: 305
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/brain/aww307
    Best OA location URL: https://academic.oup.com/brain/article-pdf/140/2/287/24174630/aww307.pdf
    Citation Count: 153
  • Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients
    2011
    Summary Details
    OPEN
    Title: Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients
    Author(s): Hua She, Qian Yang, Kennie R. Shepherd, Yoland Smith, Gary W. Miller, Claudia Testa, Zixu Mao
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Vol: 121
    Issue #: 3
    Start Page: 930
    End Page: 940
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1172/jci43871
    Citation Count: 152
  • A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy
    2014
    Summary Details
    OPEN
    Title: A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy
    Author(s): Franziska Richter, Sheila M. Fleming, Melanie B. Watson, Vincent Lemesre, Lee Pellegrino, Brian Ranes, Chunni Zhu, Farzad Mortazavi, Caitlin Mulligan, Pedrom C. Sioshansi, Sindalana Hean, Krystal De La Rosa, Richie Khanna, John J. Flanagan, David J. Lockhart, Brandon A. Wustman, Sean W. Clark, Marie‐Françoise Chesselet
    Journal Name: Neurotherapeutics
    Publisher: Elsevier BV
    Vol: 11
    Issue #: 4
    Start Page: 840
    End Page: 856
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s13311-014-0294-x
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s13311-014-0294-x.pdf
    Citation Count: 98
  • Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells
    2009
    Summary Details
    OPEN
    Title: Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells
    Author(s): Marta Biagioli, Milena Pinto, Daniela Cesselli, Marta Zaninello, Dejan Lazarević, Paola Roncaglia, Roberto Simone, Christina Vlachouli, Charles Plessy, Nicolas Bertin, Antonio Paolo Beltrami, Kazuto Kobayashi, Vittorio Gallo, Claudio Santoro, Isidró Ferrer, Stefano Rivella, Carlo Alberto Beltrami, Piero Carninci, Elio Raviola, Stefano Gustincich
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 106
    Issue #: 36
    Start Page: 15454
    End Page: 15459
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0813216106
    Best OA location URL: http://www.pnas.org/content/106/36/15454.full.pdf
    Citation Count: 260
  • Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson’s disease
    2006
    Summary Details
    OPEN
    Title: Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson’s disease
    Author(s): Todd Sherer, Jason R. Richardson, Claudia Testa, Byoung Boo Seo, Alexander Panov, Takao Yagi, Akemi Matsuno‐Yagi, Gary W. Miller, J. Timothy Greenamyre
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 100
    Issue #: 6
    Start Page: 1469
    End Page: 1479
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/j.1471-4159.2006.04333.x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8669833
    Citation Count: 323
  • Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease
    2011
    Summary Details
    OPEN
    Title: Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease
    Author(s): Joshua Shulman, Joyce Y. Tung, Elizabeth H. Dorfman, Amy K. Kiefer, Emily M. Drabant, Uta Francke, Joanna L. Mountain, Samuel M. Goldman, Caroline M. Tanner, J. William Langston, Anne Wojcicki, Nicholas Eriksson
    Journal Name: PLoS Genetics
    Publisher: Public Library of Science (PLoS)
    Vol: 7
    Issue #: 6
    Start Page: e1002141
    End Page: e1002141
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pgen.1002141
    Best OA location URL: https://escholarship.org/uc/item/1zw763wg
    Citation Count: 520
  • Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    2017
    Summary Details
    OPEN
    Title: Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    Author(s): Malte Gersch, Christina Gladkova, Alexander F. Schubert, Martin A. Michel, Sarah Maslen, David Komander
    Journal Name: Nature Structural & Molecular Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 24
    Issue #: 11
    Start Page: 920
    End Page: 930
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nsmb.3475
    Best OA location URL: http://doi.org/10.1038/nsmb.3475
    Citation Count: 201
  • Clinical signs in functional (psychogenic) gait disorders: a brief survey
    2016
    Summary Details
    OPEN
    Title: Clinical signs in functional (psychogenic) gait disorders: a brief survey
    Author(s): Leonard L. Sokol, Alberto J. Espay
    Journal Name: Journal of Clinical Movement Disorders
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s40734-016-0031-1
    Best OA location URL: https://clinicalmovementdisorders.biomedcentral.com/counter/pdf/10.1186/s40734-016-0031-1
    Citation Count: 23
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