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MJFF Publications

5351 - 5400 of 6420 Results
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  • Summary Details
    OPEN
    Title: Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acs.jmedchem.5b01780
    Citation Count: 15
  • Summary Details
    OPEN
    Title: Deep Learning With EEG Spectrograms in Rapid Eye Movement Behavior Disorder
    Journal Name: Frontiers in Neurology
    Publisher: Frontiers Media SA
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fneur.2019.00806
    Citation Count: 98
  • Summary Details
    OPEN
    Title: α‐Synuclein in Plasma‐Derived Extracellular Vesicles Is a Potential Biomarker of Parkinson's Disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mds.28639
    Citation Count: 83
  • Summary Details
    OPEN
    Title: Cargo proteins of plasma astrocyte‐derived exosomes in Alzheimer's disease
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1096/fj.201600756r
    Citation Count: 345
  • Summary Details
    OPEN
    Title: Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy
    Journal Name: Translational Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s40035-019-0164-x
    Citation Count: 145
  • Summary Details
    OPEN
    Title: Retinal Thickness Predicts the Risk of Cognitive Decline in Parkinson Disease
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1002/ana.25944
    Citation Count: 63
  • Summary Details
    OPEN
    Title: Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1126/sciadv.aaz9360
    Citation Count: 310
  • Summary Details
    OPEN
    Title: TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.celrep.2021.108895
    Citation Count: 49
  • Summary Details
    OPEN
    Title: VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites
    Journal Name: Journal of Cell Biology
    Publisher: Rockefeller University Press
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa, cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1083/jcb.201807019
    Citation Count: 527
  • Summary Details
    OPEN
    Title: Penetrance estimate of LRRK2 p.G2019S mutation in individuals of non‐Ashkenazi Jewish ancestry
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27059
    Citation Count: 151
  • Summary Details
    OPEN
    Title: Genome-wide association study and functional validation implicates JADE1 in tauopathy
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00401-021-02379-z
    Citation Count: 32
  • Summary Details
    OPEN
    Title: Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes
    Journal Name: Cell Systems
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.cels.2017.02.009
    Citation Count: 113
  • Summary Details
    OPEN
    Title: An application of generalized matrix learning vector quantization in neuroimaging
    Journal Name: Computer Methods and Programs in Biomedicine
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.cmpb.2020.105708
    Citation Count: 17
  • Summary Details
    OPEN
    Title: Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aah4066
    Citation Count: 719
  • Summary Details
    OPEN
    Title: Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd, cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/alz.13859
    Citation Count: 971
  • Summary Details
    OPEN
    Title: A History of Senile Plaques: From Alzheimer to Amyloid Imaging
    Journal Name: Journal of Neuropathology & Experimental Neurology
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/jnen/nlac030
    Citation Count: 26
  • Summary Details
    OPEN
    Title: A lipid switch unlocks Parkinson’s disease-associated ATP13A2
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1508220112
    Citation Count: 91
  • Summary Details
    OPEN
    Title: Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by, cc-by
    DOI - Digital Object Identifier: 10.1016/j.celrep.2023.112448
    Citation Count: 28
  • Summary Details
    OPEN
    Title: The Amplification of Alpha‐Synuclein Amyloid Fibrils is Suppressed under Fully Quiescent Conditions
    Journal Name: Angewandte Chemie International Edition
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1002/anie.202419173
    Citation Count: 3
  • Summary Details
    OPEN
    Title: MR‐based age‐related effects on the striatum, globus pallidus, and thalamus in healthy individuals across the adult lifespan
    Journal Name: Human Brain Mapping
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1002/hbm.24771
    Citation Count: 68
  • Summary Details
    OPEN
    Title: The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2019.113062
    Citation Count: 14
  • Summary Details
    OPEN
    Title: Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor impairment and cortical dysfunction, independent of protein aggregation
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1093/hmg/ddac035
    Citation Count: 25
  • Summary Details
    OPEN
    Title: Diabetes mellitus is independently associated with more severe cognitive impairment in Parkinson disease
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2014.10.008
    Citation Count: 103
  • Summary Details
    OPEN
    Title: Cognitive impairment in Parkinson's disease is associated with Default Mode Network subsystem connectivity and cerebrospinal fluid Aβ
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2021.01.002
    Citation Count: 29
  • Summary Details
    OPEN
    Title: A multivariate nonlinear mixed effects model for longitudinal image analysis: Application to amyloid imaging
    Journal Name: NeuroImage
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuroimage.2016.04.001
    Citation Count: 85
  • Summary Details
    OPEN
    Title: Differentially Expressed Circular RNAs in Peripheral Blood Mononuclear Cells of Patients with Parkinson's Disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mds.28467
    Citation Count: 55
  • Summary Details
    OPEN
    Title: Parkinson’s disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-025-00964-7
    Citation Count: 5
  • Summary Details
    OPEN
    Title: Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1073/pnas.2313540121
    Citation Count: 31
  • Summary Details
    OPEN
    Title: Cognitive phenotypes in parkinson's disease differ in terms of brain‐network organization and connectivity
    Journal Name: Human Brain Mapping
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/hbm.23474
    Citation Count: 88
  • Summary Details
    OPEN
    Title: Initiation and propagation of α-synuclein aggregation in the nervous system
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-020-00368-6
    Citation Count: 245
  • Summary Details
    OPEN
    Title: The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domain
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1073/pnas.1900289116
    Citation Count: 78
  • Summary Details
    OPEN
    Title: Mild cognitive impairment as a risk factor for Parkinson's disease dementia
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27002
    Citation Count: 145
  • Summary Details
    OPEN
    Title: Pathological α-synuclein perturbs nuclear integrity
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1016/j.nbd.2025.107028
    Citation Count: 0
  • Summary Details
    OPEN
    Title: A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein
    Journal Name: Neurotherapeutics
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: other-oa
    DOI - Digital Object Identifier: 10.1007/s13311-017-0544-9
    Citation Count: 54
  • Summary Details
    OPEN
    Title: Identification of Parkinson’s disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data
    Journal Name: npj Digital Medicine
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41746-024-01175-9
    Citation Count: 20
  • Summary Details
    OPEN
    Title: Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.celrep.2017.12.066
    Citation Count: 587
  • Summary Details
    OPEN
    Title: Mitochondrial complex I deficiency induces Alzheimer's disease–like signatures that are reversible by targeted therapy
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/alz.70519
    Citation Count: 1
  • Summary Details
    OPEN
    Title: TMEM106B haplotypes have distinct gene expression patterns in aged brain
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-018-0268-2
    Citation Count: 37
  • Summary Details
    OPEN
    Title: Oligomeric α-Synuclein Is Increased in Basal Tears of Parkinson’S Patients
    Journal Name: Biomarkers in Medicine
    Publisher: Informa UK Limited
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.2217/bmm-2019-0167
    Citation Count: 51
  • Summary Details
    OPEN
    Title: Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-024-02706-0
    Citation Count: 41
  • Summary Details
    OPEN
    Title: α-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson’s disease from multiple system atrophy
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-021-02324-0
    Citation Count: 132
  • Summary Details
    OPEN
    Title: Fine mapping of the HLA locus in Parkinson’s disease in Europeans
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-021-00231-5
    Citation Count: 68
  • Summary Details
    OPEN
    Title: The nosology of tardive syndromes
    Journal Name: Journal of the Neurological Sciences
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.jns.2018.02.008
    Citation Count: 75
  • Summary Details
    OPEN
    Title: Plasma-borne indicators of inflammasome activity in Parkinson’s disease patients
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-020-00147-6
    Citation Count: 67
  • Summary Details
    OPEN
    Title: Incidence of Parkinson disease in North America
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-022-00410-y
    Citation Count: 220
  • Summary Details
    OPEN
    Title: Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mds.27361
    Citation Count: 182
  • Summary Details
    OPEN
    Title: Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-021-00491-y
    Citation Count: 50
  • Summary Details
    OPEN
    Title: Levels of Oligomeric α-Synuclein in Reflex Tears Distinguish Parkinson'S Disease Patients From Healthy Controls
    Journal Name: Biomarkers in Medicine
    Publisher: Informa UK Limited
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.2217/bmm-2019-0315
    Citation Count: 35
  • Summary Details
    OPEN
    Title: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.7554/elife.12813
    Citation Count: 979
  • Summary Details
    OPEN
    Title: Synapsin III is a key component of α‐synuclein fibrils in Lewy bodies of PD brains
    Journal Name: Brain Pathology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/bpa.12587
    Citation Count: 42
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