2001 - 2050 of 6433 Results
Title
Year
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OPENTitle: Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotypingJournal Name: Nature ProtocolsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 11Start Page: 1860End Page: 1896Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nprot.2015.122Citation Count: 258
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OPENTitle: LRRK2 levels in immune cells are increased in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-017-0010-8Best OA location URL: https://doi.org/10.1038/s41531-017-0010-8Citation Count: 237
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OPENTitle: Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-017-0007-3Best OA location URL: https://www.nature.com/articles/s41531-017-0007-3.pdfCitation Count: 32
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OPENTitle: Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S miceJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 41Issue #: 3Start Page: 706End Page: 716Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2010.12.008Citation Count: 185
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OPENTitle: Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s DiseaseJournal Name: Neurotoxicity ResearchPublisher: Springer Science and Business Media LLCVol: 19Issue #: 1Start Page: 63End Page: 72Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s12640-009-9140-zCitation Count: 234
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OPENTitle: The alpha-synuclein 5′untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and PosiphenJournal Name: Journal of Neural TransmissionPublisher: Springer Science and Business Media LLCVol: 118Issue #: 3Start Page: 493End Page: 507Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00702-010-0513-5Citation Count: 71
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OPENTitle: Vascular endothelial growth factor is upregulated by l-dopa in the parkinsonian brain: implications for the development of dyskinesiaJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 134Issue #: 8Start Page: 2339End Page: 2357Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awr165Best OA location URL: https://academic.oup.com/brain/article-pdf/134/8/2339/13735225/awr165.pdfCitation Count: 134
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OPENTitle: Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-SynucleinJournal Name: Applied SciencesPublisher: MDPI AGVol: 4Issue #: 1Start Page: 66End Page: 78Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/app4010066Best OA location URL: https://www.mdpi.com/2076-3417/4/1/66/pdf?version=1395063831Citation Count: 55
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OPENTitle: Discovery of Potent, Novel Nrf2 Inducers Via Quantum Modeling, Virtual Screening, and In Vitro Experimental ValidationJournal Name: Chemical Biology & Drug DesignPublisher: WileyVol: 80Issue #: 6Start Page: 810End Page: 820Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/cbdd.12040Citation Count: 16
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OPENTitle: Increasing the use of mobile technology–derived endpoints in clinical trialsJournal Name: Clinical TrialsPublisher: SAGE PublicationsVol: 15Issue #: 3Start Page: 313End Page: 315Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1177/1740774518755393Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/1740774518755393Citation Count: 23
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OPENTitle: Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTPJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 105Issue #: 5Start Page: 1716End Page: 1721Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0705363105Best OA location URL: http://doi.org/10.1073/pnas.0705363105Citation Count: 249
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OPENTitle: Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseasesJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 21Issue #: 15Start Page: 3500End Page: 3512Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/dds161Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3392107Citation Count: 226
- The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?2017OPENTitle: The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?Journal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-016-0002-0Best OA location URL: https://www.nature.com/articles/s41531-016-0002-0.pdfCitation Count: 475
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OPENTitle: The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseasesJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 109Issue #:Start Page: 226End Page: 248Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nbd.2016.12.013Best OA location URL: https://doi.org/10.1016/j.nbd.2016.12.013Citation Count: 238
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OPENTitle: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 110Issue #: 1Start Page: 300End Page: 305Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1217296110Best OA location URL: https://www.pnas.org/content/pnas/110/1/300.full.pdfCitation Count: 116
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OPENTitle: Computational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synucleinJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-018-35464-7Best OA location URL: https://www.nature.com/articles/s41598-018-35464-7.pdfCitation Count: 40
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OPENTitle: Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 101Issue #: 50Start Page: 17510End Page: 17515Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0405313101Best OA location URL: http://doi.org/10.1073/pnas.0405313101Citation Count: 324
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OPENTitle: Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long termJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 135Issue #: 1Start Page: 65End Page: 83Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-017-1792-9Best OA location URL: https://link.springer.com/content/pdf/10.1007%2Fs00401-017-1792-9.pdfCitation Count: 184
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OPENTitle: CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonismJournal Name: Journal of NeurochemistryPublisher: WileyVol: 95Issue #: 4Start Page: 974End Page: 986Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2005.03428.xCitation Count: 285
- β‐amyloid and postural instability and gait difficulty in Parkinson's disease at risk for dementia2012OPENTitle: β‐amyloid and postural instability and gait difficulty in Parkinson's disease at risk for dementiaJournal Name: Movement DisordersPublisher: WileyVol: 28Issue #: 3Start Page: 296End Page: 301Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25213Best OA location URL: https://hdl.handle.net/2027.42/97160Citation Count: 89
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OPENTitle: Translation Initiator EIF4G1 Mutations in Familial Parkinson DiseaseJournal Name: The American Journal of Human GeneticsPublisher: Elsevier BVVol: 89Issue #: 3Start Page: 398End Page: 406Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.ajhg.2011.08.009Best OA location URL: http://www.cell.com/article/S0002929711003594/pdfCitation Count: 286
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OPENTitle: A Genome‐Wide Linkage Screen in the Amish with Parkinson Disease Points to Chromosome 6Journal Name: Annals of Human GeneticsPublisher: WileyVol: 75Issue #: 3Start Page: 351End Page: 358Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1469-1809.2011.00643.xBest OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1469-1809.2011.00643.xCitation Count: 10
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OPENTitle: Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative DiseasesJournal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 74Issue #: 9Start Page: 934End Page: 942Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/nen.0000000000000235Best OA location URL: https://academic.oup.com/jnen/article-pdf/74/9/934/8146595/74-9-934.pdfCitation Count: 13
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OPENTitle: Generation of Stable Transgenic C. elegans Using MicroinjectionJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 18Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/833Best OA location URL: https://www.jove.com/pdf/833/generation-of-stable-transgenic-c-elegans-using-microinjectionCitation Count: 88
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OPENTitle: Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed inXenopus laevisoocytesJournal Name: The Journal of PhysiologyPublisher: WileyVol: 586Issue #: 1Start Page: 227End Page: 245Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1113/jphysiol.2007.143172Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2375544Citation Count: 97
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OPENTitle: Application of a C. elegans Dopamine Neuron Degeneration Assay for the Validation of Potential Parkinson's Disease GenesJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 17Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/835Best OA location URL: https://www.jove.com/pdf/835/application-c-elegans-dopamine-neuron-degeneration-assay-forCitation Count: 46
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OPENTitle: Host and Microbial Factors in Regulation of T Cells in the IntestineJournal Name: Frontiers in ImmunologyPublisher: Frontiers Media SAVol: 4Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fimmu.2013.00141Best OA location URL: https://www.frontiersin.org/articles/10.3389/fimmu.2013.00141/pdfCitation Count: 18
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OPENTitle: Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP ExpressionJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 120Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/54981Best OA location URL: https://www.jove.com/pdf/54981/reliable-identification-living-dopaminergic-neurons-midbrain-culturesCitation Count: 9
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OPENTitle: Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free AssaysJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 126Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/55361Best OA location URL: http://doi.org/10.3791/55361Citation Count: 7
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OPENTitle: Subject-specific computational modeling of DBS in the PPTg areaJournal Name: Frontiers in Computational NeurosciencePublisher: Frontiers Media SAVol: 9Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fncom.2015.00093Best OA location URL: https://doi.org/10.3389/fncom.2015.00093Citation Count: 10
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OPENTitle: Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive PhosphateJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 79Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/50523Best OA location URL: https://www.jove.com/pdf/50523/metabolic-labeling-leucine-rich-repeat-kinases-1-2-with-radioactiveCitation Count: 4
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OPENTitle: Detection of Protein UbiquitinationJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 30Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/1293Best OA location URL: https://www.jove.com/pdf/1293/detection-of-protein-ubiquitinationCitation Count: 95
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OPENTitle: The synaptic impact of the host immune response in a parkinsonian allograft rat model: Influence on graft-derived aberrant behaviorsJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 32Issue #: 2Start Page: 229End Page: 242Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2008.06.018Best OA location URL: http://doi.org/10.1016/j.nbd.2008.06.018Citation Count: 62
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OPENTitle: Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced parkinsonismJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 30Issue #: 3Start Page: 430End Page: 438Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2008.02.011Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2605654Citation Count: 63
- Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRI2017OPENTitle: Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRIJournal Name: Nature ProtocolsPublisher: Springer Science and Business Media LLCVol: 12Issue #: 10Start Page: 2050End Page: 2080Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nprot.2017.081Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6185898Citation Count: 143
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OPENTitle: Genetic and Clinical Features of Progranulin-Associated Frontotemporal Lobar DegenerationJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 68Issue #: 4Start Page: 488End Page: 488Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2011.53Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3160280Citation Count: 115
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OPENTitle: Reduced Uptake of FDOPA PET in End-stage Liver Disease With Elevated Manganese LevelsJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 69Issue #: 3Start Page: 394End Page: 394Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2011.771Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3644556Citation Count: 26
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OPENTitle: Testing NF-κB-based Therapy in Hemiparkinsonian MonkeysJournal Name: Journal of Neuroimmune PharmacologyPublisher: Springer Science and Business Media LLCVol: 7Issue #: 3Start Page: 544End Page: 556Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s11481-012-9377-9Citation Count: 40
- Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study.2006OPENTitle: Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study.Journal Name: Journal of NeuroinflammationPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page: 29End Page: 29Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1742-2094-3-29Best OA location URL: https://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/1742-2094-3-29Citation Count: 138
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OPENTitle: RGS10 exerts a neuroprotective role through the PKA/c‐AMP response‐element (CREB) pathway in dopaminergic neuron‐like cellsJournal Name: Journal of NeurochemistryPublisher: WileyVol: 122Issue #: 2Start Page: 333End Page: 343Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2012.07780.xBest OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3435458Citation Count: 38
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OPENTitle: Transgenic mice expressing S129 phosphorylation mutations in α-synucleinJournal Name: Neuroscience LettersPublisher: Elsevier BVVol: 563Issue #:Start Page: 96End Page: 100Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neulet.2014.01.033Best OA location URL: http://doi.org/10.1016/j.neulet.2014.01.033Citation Count: 14
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OPENTitle: Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 DomainJournal Name: Molecular and Cellular BiologyPublisher: Informa UK LimitedVol: 34Issue #: 12Start Page: 2147End Page: 2161Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1128/mcb.00914-13Best OA location URL: https://mcb.asm.org/content/mcb/34/12/2147.full.pdfCitation Count: 99
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OPENTitle: Epidemiology of Parkinson's diseaseJournal Name: Handbook of Clinical NeurologyPublisher: ElsevierVol:Issue #:Start Page: 129End Page: 151Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/s0072-9752(07)83006-5Citation Count: 131
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OPENTitle: Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 115Issue #: 11Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1713849115Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5856519Citation Count: 197
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OPENTitle: Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodentsJournal Name: Journal of Comparative NeurologyPublisher: WileyVol: 522Issue #: 11Start Page: 2465End Page: 2480Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/cne.23583Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4076169Citation Count: 127
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OPENTitle: A Role for Neuronal Alpha-Synuclein in Gastrointestinal ImmunityJournal Name: Journal of Innate ImmunityPublisher: S. Karger AGVol: 9Issue #: 5Start Page: 456End Page: 463Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1159/000477990Best OA location URL: https://www.karger.com/Article/Pdf/477990Citation Count: 252
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OPENTitle: Anatomy of graft-induced dyskinesias: Circuit remodeling in the parkinsonian striatumJournal Name: Basal GangliaPublisher: Elsevier BVVol: 2Issue #: 1Start Page: 15End Page: 30Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.baga.2012.01.002Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3375918Citation Count: 13
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OPENTitle: Parkinson's disease, cortical dysfunction, and alpha‐synucleinJournal Name: Movement DisordersPublisher: WileyVol: 26Issue #: 8Start Page: 1436End Page: 1442Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.23697Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3154995Citation Count: 23
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OPENTitle: Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cellsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-017-10501-zBest OA location URL: https://www.nature.com/articles/s41598-017-10501-z.pdfCitation Count: 97
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OPENTitle: HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasisJournal Name: Cell Death & DifferentiationPublisher: Springer Science and Business Media LLCVol: 13Issue #: 4Start Page: 539End Page: 550Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/sj.cdd.4401769Best OA location URL: https://www.nature.com/articles/4401769.pdfCitation Count: 432