3601 - 3650 of 6284 Results
Title
Year
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OPENTitle: Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's diseaseJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 112Issue #:Start Page: 136End Page: 148Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1016/j.nbd.2018.01.004Best OA location URL: https://repositorio.uchile.cl/handle/2250/167345Citation Count: 145
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OPENTitle: Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in MiceJournal Name: EBioMedicinePublisher: Elsevier BVVol: 29Issue #:Start Page: 13End Page: 22Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.ebiom.2018.01.035Best OA location URL: http://www.thelancet.com/article/S2352396418300392/pdfCitation Count: 28
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OPENTitle: Striatal and Cortical β‐Amyloidopathy and Cognition in Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 1Start Page: 111End Page: 117Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26369Best OA location URL: http://doi.org/10.1002/mds.26369Citation Count: 59
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OPENTitle: An artificial intelligence-derived metabolic network predicts psychosis in Alzheimer’s diseaseJournal Name: Brain CommunicationsPublisher: Oxford University Press (OUP)Vol: 7Issue #: 3Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/braincomms/fcaf159Best OA location URL: https://doi.org/10.1093/braincomms/fcaf159Citation Count: 0
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OPENTitle: Associations between daily-living physical activity and laboratory-based assessments of motor severity in patients with falls and Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 62Issue #:Start Page: 85End Page: 90Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.01.022Best OA location URL: http://www.prd-journal.com/article/S1353802019300227/pdfCitation Count: 81
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OPENTitle: Transcriptional programs mediating neuronal toxicity and altered glial–neuronal signaling in aDrosophilaknock-in tauopathy modelJournal Name: Genome ResearchPublisher: Cold Spring Harbor LaboratoryVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1101/gr.278576.123Best OA location URL: https://genome.cshlp.org/content/early/2024/04/09/gr.278576.123.full.pdfCitation Count: 5
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OPENTitle: LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent mannerJournal Name: Cell Death & DiseasePublisher: Springer Science and Business Media LLCVol: 14Issue #: 7Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41419-023-05964-0Best OA location URL: https://www.nature.com/articles/s41419-023-05964-0.pdfCitation Count: 15
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OPENTitle: Vestibular Sensory Conflict During Postural Control, Freezing of Gait, and Falls in Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 37Issue #: 11Start Page: 2257End Page: 2262Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/mds.29189Best OA location URL: https://doi.org/10.1002/mds.29189Citation Count: 22
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OPENTitle: Ipsilateral deficits of dopaminergic neurotransmission in Parkinson's diseaseJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 3Issue #: 1Start Page: 21End Page: 26Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/acn3.268Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.268Citation Count: 46
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OPENTitle: Central and peripheral α‐synuclein in Parkinson disease detected by seed amplification assayJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 10Issue #: 5Start Page: 696End Page: 705Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/acn3.51753Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.51753Citation Count: 28
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OPENTitle: Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of deliveryJournal Name: Journal of Controlled ReleasePublisher: Elsevier BVVol: 286Issue #:Start Page: 467End Page: 484Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jconrel.2018.08.006Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7234798Citation Count: 87
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OPENTitle: L-DOPA functionalized, multi-branched gold nanoparticles as brain-targeted nano-vehiclesJournal Name: Nanomedicine: Nanotechnology, Biology and MedicinePublisher: Elsevier BVVol: 15Issue #: 1Start Page: 1End Page: 11Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nano.2018.08.011Best OA location URL: http://hdl.handle.net/10044/1/63483Citation Count: 88
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OPENTitle: The neuro-toxin MPTP does not prevent reproduction in marmosetsJournal Name: MNI Open ResearchPublisher: F1000 Research LtdVol: 3Issue #:Start Page: 2End Page: 2Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.12688/mniopenres.12818.2Best OA location URL: https://mniopenresearch.org/articles/3-2/v2/pdfCitation Count: 0
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OPENTitle: Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain AgingJournal Name: Cell ReportsPublisher: Elsevier BVVol: 18Issue #: 2Start Page: 557End Page: 570Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.celrep.2016.12.011Best OA location URL: http://www.cell.com/article/S2211124716316849/pdfCitation Count: 381
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OPENTitle: Anxiety in Parkinson's disease is associated with changes in the brain fear circuitJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 80Issue #:Start Page: 89End Page: 97Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2020.09.020Best OA location URL: http://www.prd-journal.com/article/S1353802020307343/pdfCitation Count: 30
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OPENTitle: Longitudinal Assessment of Parkinson’s Motor Symptoms and Dopaminergic Dysfunction Patterns Using DaTSCANJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 12Issue #:Start Page: 100331End Page: 100331Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1016/j.prdoa.2025.100331Best OA location URL: https://doi.org/10.1016/j.prdoa.2025.100331Citation Count: 1
- Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM502024OPENTitle: Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50Journal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 13Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.99914Best OA location URL: https://doi.org/10.7554/elife.99914Citation Count: 3
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OPENTitle: Prevalence of GBA p.K198E mutation in Colombian and Hispanic populationsJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 73Issue #:Start Page: 16End Page: 18Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2020.03.008Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7528207Citation Count: 7
- ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system2021OPENTitle: ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation systemJournal Name: Molecular CellPublisher: Elsevier BVVol: 81Issue #: 9Start Page: 2013End Page: 2030.e9Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.molcel.2021.03.001Best OA location URL: http://www.cell.com/article/S1097276521001696/pdfCitation Count: 70
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OPENTitle: Clinical severity in Parkinson’s disease is determined by decline in cortical compensationJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 147Issue #: 3Start Page: 871End Page: 886Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/brain/awad325Best OA location URL: https://academic.oup.com/brain/advance-article-pdf/doi/10.1093/brain/awad325/51777747/awad325.pdfCitation Count: 27
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OPENTitle: Pimavanserin versus quetiapine for the treatment of psychosis in Parkinson's disease and dementia with Lewy bodiesJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 69Issue #:Start Page: 119End Page: 124Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.11.009Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7061324Citation Count: 35
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OPENTitle: Cheek cell–derived α-synuclein and DJ-1 do not differentiate Parkinson's disease from controlJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 35Issue #: 2Start Page: 418End Page: 420Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.08.008Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2013.08.008Citation Count: 30
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OPENTitle: Multimodal MRI evaluation of parkinsonian limbic pathologiesJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 76Issue #:Start Page: 194End Page: 200Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2019.01.004Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6461740Citation Count: 14
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OPENTitle: Using a stable protein scaffold to display peptides that bind to alpha‐synuclein fibrilsJournal Name: Protein SciencePublisher: WileyVol: 34Issue #: 6Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/pro.70150Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pro.70150Citation Count: 0
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OPENTitle: Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapyJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-018-0245-9Best OA location URL: https://doi.org/10.1186/s13024-018-0245-9Citation Count: 65
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OPENTitle: Clinimetric Analysis of the Motor Section of the Progressive Supranuclear Palsy Rating Scale: Reliability and Factor AnalysisJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 3Issue #: 1Start Page: 65End Page: 67Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12243Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12243Citation Count: 9
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OPENTitle: Daily-Living Freezing of Gait as Quantified Using Wearables in People With Parkinson Disease: Comparison With Self-Report and Provocation TestsJournal Name: Physical TherapyPublisher: Oxford University Press (OUP)Vol: 102Issue #: 12Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/ptj/pzac129Best OA location URL: https://academic.oup.com/ptj/article-pdf/102/12/pzac129/48129224/pzac129.pdfCitation Count: 15
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OPENTitle: Evidence for an Additive Neurorestorative Effect of Simultaneously Administered CDNF and GDNF in Hemiparkinsonian Rats: Implications for Different Mechanism of ActionJournal Name: eneuroPublisher: Society for NeuroscienceVol: 4Issue #: 1Start Page: ENEURO.0117End Page: 16.2017Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1523/eneuro.0117-16.2017Best OA location URL: https://www.eneuro.org/content/eneuro/4/1/ENEURO.0117-16.2017.full.pdfCitation Count: 52
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OPENTitle: The Systemic Synuclein Sampling Study: Toward a Biomarker for Parkinson’s DiseaseJournal Name: Biomarkers in MedicinePublisher: Informa UK LimitedVol: 11Issue #: 4Start Page: 359End Page: 368Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.2217/bmm-2016-0366Best OA location URL: https://www.futuremedicine.com/doi/pdf/10.2217/bmm-2016-0366Citation Count: 52
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OPENTitle: Feasibility of repeat and bilateral submandibular gland needle biopsies in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 68Issue #:Start Page: 69End Page: 72Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.10.006Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9979781Citation Count: 17
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OPENTitle: Identification of small molecule dimethyoxyphenyl piperazine inhibitors of alpha-synuclein fibril growthJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/s41598-025-17658-yBest OA location URL: https://www.nature.com/articles/s41598-025-17658-y.pdfCitation Count: 0
- LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains2022OPENTitle: LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domainsJournal Name: PLOS BiologyPublisher: Public Library of Science (PLoS)Vol: 20Issue #: 2Start Page: e3001427End Page: e3001427Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pbio.3001427Best OA location URL: https://doi.org/10.1371/journal.pbio.3001427Citation Count: 25
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OPENTitle: DNA methylation changes associated with Parkinson’s disease progression: outcomes from the first longitudinal genome-wide methylation analysis in bloodJournal Name: EpigeneticsPublisher: Informa UK LimitedVol: 14Issue #: 4Start Page: 365End Page: 382Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/15592294.2019.1588682Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15592294.2019.1588682?needAccess=trueCitation Count: 78
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OPENTitle: Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in miceJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 6Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.28377Best OA location URL: https://doi.org/10.7554/elife.28377Citation Count: 96
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OPENTitle: At a crossroads: Revisiting mild cognitive impairment in Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 33Issue #: 4Start Page: 501End Page: 502Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27310Best OA location URL: https://escholarship.org/content/qt6ds4v3z7/qt6ds4v3z7.pdfCitation Count: 1
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OPENTitle: The Future of GDNF in Parkinson's DiseaseJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 12Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2020.593572Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2020.593572/pdfCitation Count: 43
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OPENTitle: Serum IGF-1 is associated with cognitive functions in early, drug-naïve Parkinson’s diseaseJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 12Issue #: 10Start Page: e0186508End Page: e0186508Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0186508Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0186508&type=printableCitation Count: 39
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OPENTitle: TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tauJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 5Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.7554/elife.19809Best OA location URL: https://doi.org/10.7554/elife.19809Citation Count: 122
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OPENTitle: General anaesthesia decreases the uniqueness of brain functional connectivity across individuals and speciesJournal Name: Nature Human BehaviourPublisher: Springer Science and Business Media LLCVol: 9Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41562-025-02121-9Best OA location URL: https://doi.org/10.1038/s41562-025-02121-9Citation Count: 2
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OPENTitle: Inhibition of LRRK2 or Casein Kinase 1 Results in LRRK2 Protein DestabilizationJournal Name: Molecular NeurobiologyPublisher: Springer Science and Business Media LLCVol: 56Issue #: 8Start Page: 5273End Page: 5286Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s12035-018-1449-2Best OA location URL: https://link.springer.com/content/pdf/10.1007/s12035-018-1449-2.pdfCitation Count: 18
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OPENTitle: Body-first versus brain-first biological subtyping of Parkinson’s diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 143Issue #: 10Start Page: 2871End Page: 2873Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awaa293Best OA location URL: https://academic.oup.com/brain/article-pdf/143/10/2871/35939469/awaa293.pdfCitation Count: 21
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OPENTitle: Rapid 2D 23Na MRI of the calf using a denoising convolutional neural networkJournal Name: Magnetic Resonance ImagingPublisher: Elsevier BVVol: 110Issue #:Start Page: 184End Page: 194Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.mri.2024.04.027Best OA location URL: https://doi.org/10.1016/j.mri.2024.04.027Citation Count: 2
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OPENTitle: GSK2578215A; A potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 17Start Page: 5625End Page: 5629Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.06.104Best OA location URL: http://doi.org/10.1016/j.bmcl.2012.06.104Citation Count: 149
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OPENTitle: Identification of rare protein disulfide isomerase gene variants in amyotrophic lateral sclerosis patientsJournal Name: GenePublisher: Elsevier BVVol: 566Issue #: 2Start Page: 158End Page: 165Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.gene.2015.04.035Best OA location URL: https://repositorio.uchile.cl/handle/2250/133590Citation Count: 73
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OPENTitle: Large-scale proteomics analysis of five brain regions from Parkinson’s disease patients with a GBA1 mutationJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-024-00645-xBest OA location URL: https://www.nature.com/articles/s41531-024-00645-x.pdfCitation Count: 6
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OPENTitle: Neurosurgeons perspective on the shift towards earlier use of deep brain stimulation for Parkinson diseaseJournal Name: Interdisciplinary NeurosurgeryPublisher: Elsevier BVVol: 25Issue #:Start Page: 101224End Page: 101224Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.inat.2021.101224Best OA location URL: https://doi.org/10.1016/j.inat.2021.101224Citation Count: 2
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OPENTitle: CLIPPERS: A Treatable Cause of Spastic AtaxiaJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 5Issue #: 2Start Page: 212End Page: 214Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12602Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12602Citation Count: 2
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OPENTitle: Brain‐Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha‐Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's DiseaseJournal Name: Advanced MaterialsPublisher: WileyVol: 35Issue #: 51Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/adma.202304654Best OA location URL: https://doi.org/10.1002/adma.202304654Citation Count: 58
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OPENTitle: Identification of a Putative α-synuclein Radioligand Using an in silico Similarity SearchJournal Name: Molecular Imaging and BiologyPublisher: Springer Science and Business Media LLCVol: 25Issue #: 4Start Page: 704End Page: 719Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s11307-023-01814-9Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/10527666Citation Count: 9
- Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease2018OPENTitle: Dissociation between urate and blood pressure in mice and in people with early Parkinson's diseaseJournal Name: EBioMedicinePublisher: Elsevier BVVol: 37Issue #:Start Page: 259End Page: 268Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.ebiom.2018.10.039Best OA location URL: http://www.thelancet.com/article/S2352396418304572/pdfCitation Count: 9