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  • Clinician-Input Study (CIS-PD): how the Fox Wearable Companion Application can influence treatment and care in Parkinson’s disease (P3.048)
    2018
    Summary Details
    RESTRICTED
    Title: Clinician-Input Study (CIS-PD): how the Fox Wearable Companion Application can influence treatment and care in Parkinson’s disease (P3.048)
    Author(s): Margaret Daeschler, Jordan J. Elm, Erin Klintworth, Michal Afek, Shira Lazar, Tanya Simuni
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 90
    Issue #: 15_supplement
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.90.15_supplement.p3.048
    Citation Count: 4
  • A potential patient stratification biomarker for Parkinson´s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
    2024
    Summary Details
    OPEN
    Title: A potential patient stratification biomarker for Parkinson´s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
    Author(s): Yahaira Naaldijk, Belén Fernández, Rachel Fasiczka, Elena Fdez, Coline Leghay, Ioana Croitoru, John B. Kwok, Yanisse Boulesnane, Amélie Vizeneux, Eugénie Mutez, Camille Calvez, A. Destée, Jean‐Marc Taymans, Ana Vinagre‐Aragón, Alberto Bergareche Yarza, Shalini Padmanabhan, Mario Delgado, Roy N. Alcalay, Zac Chatterton, Nicolas Dzamko, Glenda M. Halliday, Javier Ruiz‐Martínez, Marie‐Christine Chartier‐Harlin, Sabine Hilfiker
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-023-00624-8
    Best OA location URL: https://www.nature.com/articles/s41531-023-00624-8.pdf
    Citation Count: 15
  • The Alzheimer disease BIN1 locus as a modifier of GBA-associated Parkinson disease
    2015
    Summary Details
    RESTRICTED
    Title: The Alzheimer disease BIN1 locus as a modifier of GBA-associated Parkinson disease
    Author(s): Ziv Gan‐Or, Idan Amshalom, Anat Bar‐Shira, Mali Gana‐Weisz, Anat Mirelman, Karen Marder, Susan Bressman, Nir Giladi, Avi Orr‐Urtreger
    Journal Name: Journal of Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 262
    Issue #: 11
    Start Page: 2443
    End Page: 2447
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00415-015-7868-3
    Citation Count: 25
  • Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model
    2009
    Summary Details
    RESTRICTED
    Title: Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model
    Author(s): Ana Muñoz, Thomas Carlsson, Elisabetta Tronci, Deniz Kirik, Anders Björklund, Manolo Carta
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 219
    Issue #: 1
    Start Page: 298
    End Page: 307
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2009.05.033
    Citation Count: 93
  • Pharmacological validation of TDO as a target for Parkinson’s disease
    2021
    Summary Details
    OPEN
    Title: Pharmacological validation of TDO as a target for Parkinson’s disease
    Author(s): Paula Perez‐Pardo, Yvonne Grobben, Nicole Willemsen‐Seegers, Mitch Hartog, Michaela Tutone, Michelle Müller, Youri Adolfs, R. Jeroen Pasterkamp, Diep Vu‐Pham, Antoon M. van Doornmalen, Freek van Cauter, Joeri de Wit, Jan Gerard Sterrenburg, Joost C.M. Uitdehaag, Jos de Man, Rogier C. Buijsman, Guido J.R. Zaman, Aletta D. Kraneveld
    Journal Name: The FEBS Journal
    Publisher: Wiley
    Vol: 288
    Issue #: 14
    Start Page: 4311
    End Page: 4331
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1111/febs.15721
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.15721
    Citation Count: 22
  • Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery
    2020
    Summary Details
    OPEN
    Title: Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery
    Author(s): Susan S. Taylor, Pallavi Kaila Sharma, Jui-Hung Weng, Phillip C. Aoto, Sven H. Schmidt, Stefan Knapp, Sebastian Mathea, Friedrich W. Herberg
    Journal Name: Frontiers in Molecular Neuroscience
    Publisher: Frontiers Media SA
    Vol: 13
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnmol.2020.538219
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2020.538219/pdf
    Citation Count: 24
  • Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system
    2012
    Summary Details
    RESTRICTED
    Title: Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system
    Author(s): Ali Reza Noorian, Jennifer Rha, Dana M. Annerino, Douglas Bernhard, Georgia M. Taylor, James G. Greene
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 48
    Issue #: 1
    Start Page: 9
    End Page: 19
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2012.06.005
    Best OA location URL: https://doaj.org/article/51752686f9774ce2aae93abfd8ee862e
    Citation Count: 79
  • 4R-Cembranoid Improves Outcomes after 6-Hydroxydopamine Challenge in Both In vitro and In vivo Models of Parkinson's Disease
    2017
    Summary Details
    OPEN
    Title: 4R-Cembranoid Improves Outcomes after 6-Hydroxydopamine Challenge in Both In vitro and In vivo Models of Parkinson's Disease
    Author(s): Jing Hu, P.A. Ferchmin, Ann M. Hemmerle, Kim B. Seroogy, Vesna A. Eterović, Jiukuan Hao
    Journal Name: Frontiers in Neuroscience
    Publisher: Frontiers Media SA
    Vol: 11
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnins.2017.00272
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnins.2017.00272/pdf
    Citation Count: 19
  • Repeated Spiral Drawings in Essential Tremor: a Possible Limb-Based Measure of Motor Learning
    2018
    Summary Details
    RESTRICTED
    Title: Repeated Spiral Drawings in Essential Tremor: a Possible Limb-Based Measure of Motor Learning
    Author(s): Christine Kim, Lan Luo, Qiping Yu, Ana Mirallave, Rachel Saunders‐Pullman, Richard B. Lipton, Elan D. Louis, Seth L. Pullman
    Journal Name: The Cerebellum
    Publisher: Springer Science and Business Media LLC
    Vol: 18
    Issue #: 2
    Start Page: 178
    End Page: 187
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s12311-018-0974-x
    Citation Count: 6
  • Long-term, stable, targeted biodelivery and efficacy of GDNF from encapsulated cells in the rat and Goettingen miniature pig brain
    2020
    Summary Details
    OPEN
    Title: Long-term, stable, targeted biodelivery and efficacy of GDNF from encapsulated cells in the rat and Goettingen miniature pig brain
    Author(s): Lars U. Wahlberg, Dwaine F. Emerich, Jeffrey H. Kordower, William J. Bell, Tracie Fradet, Giovanna Paolone
    Journal Name: Current Research in Pharmacology and Drug Discovery
    Publisher: Elsevier BV
    Vol: 1
    Issue #:
    Start Page: 19
    End Page: 29
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.crphar.2020.04.001
    Best OA location URL: https://doi.org/10.1016/j.crphar.2020.04.001
    Citation Count: 11
  • Human LRRK2 G2019S mutation represses post-synaptic protein PSD95 and causes cognitive impairment in transgenic mice
    2017
    Summary Details
    OPEN
    Title: Human LRRK2 G2019S mutation represses post-synaptic protein PSD95 and causes cognitive impairment in transgenic mice
    Author(s): Samuel O. Adeosun, Xu Hou, Baoying Zheng, Heather L. Melrose, Thomas H. Mosley, Jun Ming Wang
    Journal Name: Neurobiology of Learning and Memory
    Publisher: Elsevier BV
    Vol: 142
    Issue #:
    Start Page: 182
    End Page: 189
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nlm.2017.05.001
    Best OA location URL: http://doi.org/10.1016/j.nlm.2017.05.001
    Citation Count: 13
  • Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons
    2018
    Summary Details
    OPEN
    Title: Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons
    Author(s): Sarah A. McClymont, Paul W. Hook, Alexandra I. Soto, Xylena Reed, William D. Law, Samuel J. Kerans, Eric L. Waite, Nicole Briceno, Joseph F. Thole, Michael G. Heckman, Nancy N. Diehl, Zbigniew K. Wszołek, Cedric Moore, Heng Zhu, Jennifer A. Akiyama, Diane E. Dickel, Axel Visel, L Pennacchio, Owen A. Ross, M Beer, Andrew S. McCallion
    Journal Name: The American Journal of Human Genetics
    Publisher: Elsevier BV
    Vol: 103
    Issue #: 6
    Start Page: 874
    End Page: 892
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.ajhg.2018.10.018
    Best OA location URL: http://www.cell.com/article/S0002929718303707/pdf
    Citation Count: 39
  • Epidural Spinal Cord Stimulation Improves Motor Function in Rats With Chemically Induced Parkinsonism
    2019
    Summary Details
    OPEN
    Title: Epidural Spinal Cord Stimulation Improves Motor Function in Rats With Chemically Induced Parkinsonism
    Author(s): Hui Zhong, Chunni Zhu, Yoshihiko Minegishi, Franziska Richter, Sharon Zdunowski, Roland R. Roy, Bryce Vissel, Parag Gad, Yury Gerasimenko, Marie‐Françoise Chesselet, V. Reggie Edgerton
    Journal Name: Neurorehabilitation and Neural Repair
    Publisher: SAGE Publications
    Vol: 33
    Issue #: 12
    Start Page: 1029
    End Page: 1039
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1177/1545968319876891
    Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/1545968319876891
    Citation Count: 11
  • Inhibition of glucosylceramide synthase stimulates autophagy flux in neurons
    2014
    Summary Details
    RESTRICTED
    Title: Inhibition of glucosylceramide synthase stimulates autophagy flux in neurons
    Author(s): Wei Shen, Anastasia G. Henry, Katrina L. Paumier, Li Li, Kewa Mou, John Dunlop, Zdenek Berger, Warren D. Hirst
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 129
    Issue #: 5
    Start Page: 884
    End Page: 894
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1111/jnc.12672
    Citation Count: 33
  • Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice
    2020
    Summary Details
    OPEN
    Title: Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice
    Author(s): Joanna A. Korecka, Ria Thomas, Anthony J. Hinrich, Alyssa Moskites, Zach K. Macbain, Penelope J. Hallett, Ole Isacson, Michelle L. Hastings
    Journal Name: Molecular Therapy Nucleic Acids
    Publisher: Elsevier BV
    Vol: 21
    Issue #:
    Start Page: 623
    End Page: 635
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.omtn.2020.06.027
    Best OA location URL: http://www.cell.com/article/S2162253120301888/pdf
    Citation Count: 37
  • Dopamine receptors D3 and D5 regulate CD4+T-cell activation and differentiation by modulating ERK activation and cAMP production
    2015
    Summary Details
    RESTRICTED
    Title: Dopamine receptors D3 and D5 regulate CD4+T-cell activation and differentiation by modulating ERK activation and cAMP production
    Author(s): Dafne Franz, Francisco Contreras, Hugo González, Carolina Prado, Daniela Elgueta, Claudio Figueroa, Rodrigo Pacheco
    Journal Name: Journal of Neuroimmunology
    Publisher: Elsevier BV
    Vol: 284
    Issue #:
    Start Page: 18
    End Page: 29
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.jneuroim.2015.05.003
    Citation Count: 47
  • Sex‐ and region‐dependent neuroinflammation in Alzheimer's disease
    2025
    Summary Details
    OPEN
    Title: Sex‐ and region‐dependent neuroinflammation in Alzheimer's disease
    Author(s): Maricedes Acosta‐Martínez, V. Carter, Aviram Nessim, Radha Panchal, Dalfino John, Jasbeer Dhawan, Thomas G. Beach, Geidy E. Serrano, Erin E. Sundermann, Anat Biegon
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Vol: 21
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/alz.14603
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.14603
    Citation Count: 5
  • Web-Based Assessment of Visual and Visuospatial Symptoms in Parkinson’s Disease
    2012
    Summary Details
    OPEN
    Title: Web-Based Assessment of Visual and Visuospatial Symptoms in Parkinson’s Disease
    Author(s): Melissa M. Amick, Ivy N. Miller, Sandy Neargarder, Alice Cronin–Golomb
    Journal Name: Parkinson's Disease
    Publisher: Wiley
    Vol: 2012
    Issue #:
    Start Page: 1
    End Page: 7
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1155/2012/564812
    Best OA location URL: https://downloads.hindawi.com/journals/pd/2012/564812.pdf
    Citation Count: 4
  • MAPT allele and haplotype frequencies in Nigerian Africans: Population distribution and association with Parkinson's disease risk and age at onset
    2023
    Summary Details
    OPEN
    Title: MAPT allele and haplotype frequencies in Nigerian Africans: Population distribution and association with Parkinson's disease risk and age at onset
    Author(s): Olaitan Okunoye, Oluwadamilola O. Ojo, Oladunni Abiodun, Sani Abubakar, Charles Achoru, Olaleye Adeniji, Osigwe P. Agabi, Uchechi Agulanna, Rufus Akinyemi, Mohammed Ali, Ifeyinwa Ani‐Osheku, Ohwotemu Arigbodi, Abiodun Bello, Cyril Erameh, Temitope Farombi, Bimbo Fawale, Frank Imarhiagbe, Emmanuel Iwuozo, Morenikeji Komolafe, Paul Nwani, Ernest Nwazor, Yakub Nyandaiti, Yahaya Obiabo, Olanike Odeniyi, Francis Odiase, FI Ojini, Gerald Onwuegbuzie, Godwin Osaigbovo, Nosakhare Osemwegie, Olajumoke Oshinaike, Folajimi Otubogun, Shyngle Oyakhire, Simon Ozomma, Sarah Samuel, Funmilola Taiwo, Kolawole Wahab, Yusuf Zubair, Dena Hernández, Sara Bandrés‐Ciga, Cornelis Blauwendraat, Andrew Singleton, Henry Houlden, John Hardy, Mie Rizig, Njideka Okubadejo
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 113
    Issue #:
    Start Page: 105517
    End Page: 105517
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2023.105517
    Best OA location URL: https://discovery.ucl.ac.uk/10177992/3/Hardy_MAPT%20allele%20and%20haplotype%20frequencies%20in%20Nigerian%20Africans_AAM.pdf
    Citation Count: 3
  • N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine
    2024
    Summary Details
    OPEN
    Title: N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine
    Author(s): Chuchu Wang, Chunyu Zhao, Xiao Hu, Jiali Qiang, Zhenying Liu, Jinge Gu, Shengnan Zhang, Dan Li, Yaoyang Zhang, Jacqueline Burré, Jiajie Diao, Cong Liu
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Vol: 13
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.7554/elife.97228.3
    Best OA location URL: https://doi.org/10.7554/elife.97228.3
    Citation Count: 3
  • Impact of oral textures on aspiration and changes in swallow dynamics in patients with PD with DBS
    2020
    Summary Details
    RESTRICTED
    Title: Impact of oral textures on aspiration and changes in swallow dynamics in patients with PD with DBS
    Author(s): Tao Xie, Lisa Bloom, Mahesh Padmanaban, Kazutaka Takahashi, Wenjun Kang, Abraham H. Dachman, Ellen MacCracken, Peter C. Warnke
    Journal Name: Journal of Neurology, Neurosurgery & Psychiatry
    Publisher: BMJ
    Vol: 92
    Issue #: 4
    Start Page: 447
    End Page: 449
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1136/jnnp-2020-324579
    Citation Count: 0
  • Mnemonic Similarity Task to study episodic memory in Parkinson's disease
    2020
    Summary Details
    OPEN
    Title: Mnemonic Similarity Task to study episodic memory in Parkinson's disease
    Author(s): Tanusree Das, Nessa Kim, Colin McDaniel, Kathleen L. Poston
    Journal Name: Clinical Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 3
    Issue #:
    Start Page: 100062
    End Page: 100062
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.prdoa.2020.100062
    Best OA location URL: https://doi.org/10.1016/j.prdoa.2020.100062
    Citation Count: 2
  • Defining α-synuclein species responsible for Parkinson’s disease phenotypes in mice
    2019
    Summary Details
    OPEN
    Title: Defining α-synuclein species responsible for Parkinson’s disease phenotypes in mice
    Author(s): Jessica M. Froula, Marta Castellana-Cruz, Nadia M. Anabtawi, José D. Camino, Serene W. Chen, Drake R. Thrasher, Jennifer Freire, Allen A. Yazdi, Sheila M. Fleming, Christopher M. Dobson, Janet R. Kumita, Nunilo Cremades, Laura A. Volpicelli‐Daley
    Journal Name: Journal of Biological Chemistry
    Publisher: Elsevier BV
    Vol: 294
    Issue #: 27
    Start Page: 10392
    End Page: 10406
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1074/jbc.ra119.007743
    Best OA location URL: http://www.jbc.org/article/S0021925820318330/pdf
    Citation Count: 114
  • Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
    2017
    Summary Details
    OPEN
    Title: Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
    Author(s): Marcel Scheepstra, Sebastian A. Andrei, R.M.J.M. de Vries, Femke A. Meijer, Jian‐Nong Ma, Ethan S. Burstein, Roger Olsson, Christian Ottmann, L.‐G. Milroy, Luc Brunsveld
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 8
    Issue #: 9
    Start Page: 2065
    End Page: 2077
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1021/acschemneuro.7b00216
    Best OA location URL: https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.7b00216
    Citation Count: 23
  • Chemical characterization of pro-inflammatory amyloid-beta peptides in human atherosclerotic lesions and platelets
    2011
    Summary Details
    OPEN
    Title: Chemical characterization of pro-inflammatory amyloid-beta peptides in human atherosclerotic lesions and platelets
    Author(s): Tyler A. Kokjohn, Gregory D. Van Vickle, Chera L. Maarouf, Walter M. Kalback, Jesse M. Hunter, Ian D. Daugs, Dean C. Luehrs, John Lopez, Daniel C. Brune, Lucia I. Sue, Thomas G. Beach, Eduardo M. Castaño, Alex E. Roher
    Journal Name: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
    Publisher: Elsevier BV
    Vol: 1812
    Issue #: 11
    Start Page: 1508
    End Page: 1514
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.bbadis.2011.07.004
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3185199
    Citation Count: 61
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