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  • RGS10 exerts a neuroprotective role through the PKA/c‐AMP response‐element (CREB) pathway in dopaminergic neuron‐like cells
    2012
    Summary Details
    OPEN
    Title: RGS10 exerts a neuroprotective role through the PKA/c‐AMP response‐element (CREB) pathway in dopaminergic neuron‐like cells
    Author(s): Jae‐Kyung Lee, Jaegwon Chung, Kirk M. Druey, Malú G. Tansey
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 122
    Issue #: 2
    Start Page: 333
    End Page: 343
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/j.1471-4159.2012.07780.x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3435458
    Citation Count: 38
  • Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study.
    2006
    Summary Details
    OPEN
    Title: Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study.
    Author(s): David A. Loeffler, Dianne M. Camp, Stephanie B. Conant
    Journal Name: Journal of Neuroinflammation
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page: 29
    End Page: 29
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/1742-2094-3-29
    Best OA location URL: https://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/1742-2094-3-29
    Citation Count: 138
  • Transgenic mice expressing S129 phosphorylation mutations in α-synuclein
    2014
    Summary Details
    OPEN
    Title: Transgenic mice expressing S129 phosphorylation mutations in α-synuclein
    Author(s): Valerie Drews Escobar, Yien–Ming Kuo, Bonnie M. Orrison, Benoit I. Giasson, Robert L. Nussbaum
    Journal Name: Neuroscience Letters
    Publisher: Elsevier BV
    Vol: 563
    Issue #:
    Start Page: 96
    End Page: 100
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neulet.2014.01.033
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4059511
    Citation Count: 14
  • Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain
    2014
    Summary Details
    OPEN
    Title: Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain
    Author(s): Giovanni Piccoli, Franco Onofri, Maria Daniela Cirnaru, Christoph J. O. Kaiser, Pravin Kumar Ankush Jagtap, Andreas Kastenmüller, Francesca Pischedda, Antonella Marte, Felix von Zweydorf, Andreas Vogt, Florian Giesert, Lifeng Pan, Flavia Antonucci, Christina Kiel, Mingjie Zhang, Sevil Weinkauf, Michael Sattler, Carlo Sala, Michela Matteoli, Marius Ueffing, Christian Johannes Gloeckner
    Journal Name: Molecular and Cellular Biology
    Publisher: Informa UK Limited
    Vol: 34
    Issue #: 12
    Start Page: 2147
    End Page: 2161
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1128/mcb.00914-13
    Best OA location URL: https://mcb.asm.org/content/mcb/34/12/2147.full.pdf
    Citation Count: 99
  • Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease
    2018
    Summary Details
    OPEN
    Title: Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease
    Author(s): Diego Grassi, Shannon Howard, Minghai Zhou, Natalia Diaz-Perez, Nicolai T. Urban, Debbie Guerrero‐Given, Naomi Kamasawa, Laura A. Volpicelli‐Daley, Philip V. LoGrasso, Corinne Ida Lasmézas
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 115
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1713849115
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5856519
    Citation Count: 197
  • Epidemiology of Parkinson's disease
    2007
    Summary Details
    OPEN
    Title: Epidemiology of Parkinson's disease
    Author(s): Meike Kasten, Annabel Chade, Caroline M. Tanner
    Journal Name: Handbook of Clinical Neurology
    Publisher: Elsevier
    Vol:
    Issue #:
    Start Page: 129
    End Page: 151
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/s0072-9752(07)83006-5
    Citation Count: 131
  • Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents
    2014
    Summary Details
    OPEN
    Title: Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents
    Author(s): Andrew B. West, Rita M. Cowell, João Paulo Lima Daher, Mark S. Moehle, Kelly M. Hinkle, Heather L. Melrose, David G. Standaert, Laura A. Volpicelli‐Daley
    Journal Name: Journal of Comparative Neurology
    Publisher: Wiley
    Vol: 522
    Issue #: 11
    Start Page: 2465
    End Page: 2480
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/cne.23583
    Best OA location URL: http://doi.org/10.1002/cne.23583
    Citation Count: 127
  • Anatomy of graft-induced dyskinesias: Circuit remodeling in the parkinsonian striatum
    2012
    Summary Details
    OPEN
    Title: Anatomy of graft-induced dyskinesias: Circuit remodeling in the parkinsonian striatum
    Author(s): Kathy Steece‐Collier, David J. Rademacher, Katherine E. Soderstrom
    Journal Name: Basal Ganglia
    Publisher: Elsevier BV
    Vol: 2
    Issue #: 1
    Start Page: 15
    End Page: 30
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.baga.2012.01.002
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3375918
    Citation Count: 13
  • Parkinson's disease, cortical dysfunction, and alpha‐synuclein
    2011
    Summary Details
    OPEN
    Title: Parkinson's disease, cortical dysfunction, and alpha‐synuclein
    Author(s): John N. Caviness, Lih‐Fen Lue, Thomas G. Beach, Joseph G. Hentz, Charles H. Adler, Lucia I. Sue, Ramin Sadeghi, Erika Driver‐Dunckley, Virgilio Gerald H. Evidente, Marwan N. Sabbagh, Holly A. Shill, Douglas G. Walker
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 26
    Issue #: 8
    Start Page: 1436
    End Page: 1442
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23697
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3154995
    Citation Count: 23
  • A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity
    2017
    Summary Details
    OPEN
    Title: A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity
    Author(s): Ethan D. Stolzenberg, Deborah L. Berry, De Yang, Ernest Y. Lee, Alexander Kroemer, Stuart S. Kaufman, Gerard C. L. Wong, Joost J. Oppenheim, Supti Sen, Thomas M. Fishbein, Ad Bax, Brent T. Harris, Denise Barbut, Michael Zasloff
    Journal Name: Journal of Innate Immunity
    Publisher: S. Karger AG
    Vol: 9
    Issue #: 5
    Start Page: 456
    End Page: 463
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1159/000477990
    Best OA location URL: https://www.karger.com/Article/Pdf/477990
    Citation Count: 252
  • Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells
    2017
    Summary Details
    OPEN
    Title: Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells
    Author(s): Kenneth Thirstrup, Justus C. Dächsel, Felix Oppermann, D.S. Williamson, Garrick P. Smith, Karina Fog, Kenneth Vielsted Christensen
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-017-10501-z
    Best OA location URL: https://www.nature.com/articles/s41598-017-10501-z.pdf
    Citation Count: 97
  • Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brain
    2015
    Summary Details
    OPEN
    Title: Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brain
    Author(s): Laura Civiero, Maria Daniela Cirnaru, Alexandra Beilina, Umberto Rodella, Isabella Russo, Elisa Belluzzi, Evy Lobbestael, Lauran Reyniers, Geshanthi Hondhamuni, Patrick A. Lewis, Chris Van den Haute, Veerle Baekelandt, Rina Bandopadhyay, Luigi Bubacco, Giovanni Piccoli, Mark Cookson, Jean‐Marc Taymans, Elisa Greggio
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 135
    Issue #: 6
    Start Page: 1242
    End Page: 1256
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1111/jnc.13369
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.13369
    Citation Count: 66
  • MKK6 binds and regulates expression of Parkinson’s disease‐related protein LRRK2
    2010
    Summary Details
    OPEN
    Title: MKK6 binds and regulates expression of Parkinson’s disease‐related protein LRRK2
    Author(s): Cindy H. Hsu, Diane Chan, Elisa Greggio, Shamol Saha, Maria Guillily, Andrew Ferree, Kesav Raghavan, Grace C. Shen, Lilach Segal, Hoon Ryu, Mark Cookson, Benjamin Wolozin
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 112
    Issue #: 6
    Start Page: 1593
    End Page: 1604
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/j.1471-4159.2010.06568.x
    Best OA location URL: http://doi.org/10.1111/j.1471-4159.2010.06568.x
    Citation Count: 100
  • Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region
    2013
    Summary Details
    OPEN
    Title: Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region
    Author(s): William T. Wissemann, Erin M. Hill‐Burns, Cyrus P. Zabetian, Stewart A. Factor, Nikolaos A. Patsopoulos, Bryan Höglund, Cherie L. Holcomb, Ryan Donahue, Glenys Thomson, M Kellis, Haydeh Payami
    Journal Name: The American Journal of Human Genetics
    Publisher: Elsevier BV
    Vol: 93
    Issue #: 5
    Start Page: 984
    End Page: 993
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1016/j.ajhg.2013.10.009
    Best OA location URL: http://www.cell.com/article/S0002929713004667/pdf
    Citation Count: 167
  • Lentiviral Overexpression of GRK6 Alleviates l -Dopa–Induced Dyskinesia in Experimental Parkinson’s Disease
    2010
    Summary Details
    OPEN
    Title: Lentiviral Overexpression of GRK6 Alleviates l -Dopa–Induced Dyskinesia in Experimental Parkinson’s Disease
    Author(s): M. Rafiuddin Ahmed, Amandine Berthet, Э.Р. Бычков, Grégory Porras, Qin Li, Bernard Bioulac, Yonatan T. Carl, Bertrand Bloch, Seunghyi Kook, Incarnation Aubert, Sandra Doveró, Évelyne Doudnikoff, Vsevolod V. Gurevich, Eugenia V. Gurevich, Erwan Bézard
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 2
    Issue #: 28
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.3000664
    Best OA location URL: http://doi.org/10.1126/scitranslmed.3000664
    Citation Count: 135
  • Ser(P)‐1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease
    2016
    Summary Details
    OPEN
    Title: Ser(P)‐1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease
    Author(s): Kyle Fraser, Ashlee Brooke Rawlins, Rachel G. Clark, Roy N. Alcalay, David G. Standaert, Nianjun Liu, Andrew B. West
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 31
    Issue #: 10
    Start Page: 1543
    End Page: 1550
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.26686
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5053851
    Citation Count: 181
  • Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration
    2010
    Summary Details
    OPEN
    Title: Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration
    Author(s): Maryna Baydyuk, Madeline Nguyen, Baoji Xu
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 228
    Issue #: 1
    Start Page: 118
    End Page: 125
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.12.018
    Citation Count: 75
  • Phosphorylated TDP‐43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    2008
    Summary Details
    OPEN
    Title: Phosphorylated TDP‐43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    Author(s): Masato Hasegawa, Tetsuaki Arai, Takashi Nonaka, Fuyuki Kametani, Mari Yoshida, Yoshio Hashizume, Thomas G. Beach, Emanuele Buratti, Francisco E. Baralle, Mitsuya Morita, Imaharu Nakano, Tatsuro Oda, Kuniaki Tsuchiya, Haruhiko Akiyama
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 64
    Issue #: 1
    Start Page: 60
    End Page: 70
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.21425
    Best OA location URL: http://doi.org/10.1002/ana.21425
    Citation Count: 719
  • Dopamine D3 receptor selective ligands with varying intrinsic efficacies at adenylyl cyclase inhibition and mitogenic signaling pathways
    2009
    Summary Details
    OPEN
    Title: Dopamine D3 receptor selective ligands with varying intrinsic efficacies at adenylyl cyclase inhibition and mitogenic signaling pathways
    Author(s): Michelle Taylor, Peter Grundt, Suzy A. Griffin, Amy Hauck Newman, Robert R. Luedtke
    Journal Name: Synapse
    Publisher: Wiley
    Vol: 64
    Issue #: 3
    Start Page: 251
    End Page: 266
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/syn.20725
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3821045
    Citation Count: 21
  • Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons
    2009
    Summary Details
    OPEN
    Title: Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons
    Author(s): João Paulo Lima Daher, Mingyao Ying, Rebecca Banerjee, Rebecca S. McDonald, Myriam Dumas Hahn, Lichuan Yang, M. Flint Beal, Bobby Thomas, Valina L. Dawson, Ted M. Dawson, Darren J. Moore
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/1750-1326-4-34
    Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/1750-1326-4-34
    Citation Count: 90
  • Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patients
    2016
    Summary Details
    OPEN
    Title: Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patients
    Author(s): Yoshiro Saito, Yoko Ogawa, Akihiro Matsumura, Kazumasa Saigoh, Sayoko Itoh, Kenta Sutou, M. Kobayashi, Yuichiro Mita, Mototada Shichiri, Shin Hisahara, Yasuo Hara, Harutoshi Fujimura, Hiroyuki Takamatsu, Yoshihisa Hagihara, Yasukazu Yoshida, Takao Hamakubo, Susumu Kusunoki, Shun Shimohama, Noriko Noguchi
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/srep30793
    Best OA location URL: https://www.nature.com/articles/srep30793.pdf
    Citation Count: 34
  • A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions
    2010
    Summary Details
    OPEN
    Title: A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions
    Author(s): Sheila M. Fleming, Caitlin Mulligan, Franziska Richter, Farzad Mortazavi, Vincent Lemesre, Carmen Frías, Chunni Zhu, Alistair Stewart, Illana Gozes, Bruce H. Morimoto, Marie‐Françoise Chesselet
    Journal Name: Molecular and Cellular Neuroscience
    Publisher: Elsevier BV
    Vol: 46
    Issue #: 3
    Start Page: 597
    End Page: 606
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.mcn.2010.12.011
    Citation Count: 72
  • Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutations
    2013
    Summary Details
    OPEN
    Title: Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutations
    Author(s): Roy N. Alcalay, Anat Mirelman, Rachel Saunders‐Pullman, Ming‐X Tang, Helen Mejia Santana, Deborah Raymond, Ernest Roos, Martha Orbe‐Reilly, Tanya Gurevich, Anat Bar Shira, Mali Gana Weisz, Kira Yasinovsky, Maayan Zalis, Avner Thaler, Andres Deik, Matthew J. Barrett, Jose Cabassa, Mark Groves, Ann Hunt, Naomi Lubarr, Marta San Luciano, Joan Miravite, Christina A. Palmese, Rivka Sachdev, Harini Sarva, Lawrence Severt, Vicki Shanker, Matthew Swan, Jeannie Soto‐Valencia, Brooke Johannes, Robert Ortega, Stanley Fahn, Lucien Côté, Cheryl Waters, Pietro Mazzoni, Blair Ford, Elan D. Louis, Oren Levy, Llency Rosado, Dylanis Lopez Ruiz, Tsvyatko Dorovski, Michael W. Pauciulo, William C. Nichols, Avi Orr‐Urtreger, Laurie J. Ozelius, Lorraine N. Clark, Nir Giladi, Susan Bressman, Karen Marder
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 28
    Issue #: 14
    Start Page: 1966
    End Page: 1971
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25647
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3859844
    Citation Count: 136
  • α-Synuclein Gene May Interact with Environmental Factors in Increasing Risk of Parkinson’s Disease
    2010
    Summary Details
    OPEN
    Title: α-Synuclein Gene May Interact with Environmental Factors in Increasing Risk of Parkinson’s Disease
    Author(s): Nicole M. Gatto, Shannon Rhodes, Angelika D. Manthripragada, Jeff M. Bronstein, Myles Cockburn, Matthew J. Farrer, Beate Ritz
    Journal Name: Neuroepidemiology
    Publisher: S. Karger AG
    Vol: 35
    Issue #: 3
    Start Page: 191
    End Page: 195
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1159/000315157
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2945263
    Citation Count: 62
  • Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient rats
    2014
    Summary Details
    OPEN
    Title: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient rats
    Author(s): João Paulo Lima Daher, Laura A. Volpicelli‐Daley, Jonathan P. Blackburn, Mark S. Moehle, Andrew B. West
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 111
    Issue #: 25
    Start Page: 9289
    End Page: 9294
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1403215111
    Best OA location URL: https://www.pnas.org/content/pnas/111/25/9289.full.pdf
    Citation Count: 206
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