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1676 - 1700 of 6570 Results
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  • Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation
    2018
    Summary Details
    OPEN
    Title: Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation
    Author(s): Jeannie‐Marie Leoutsakos, Haijuan Yan, William S. Anderson, Wael F. Asaad, Gordon H. Baltuch, Anna Burke, M. Mallar Chakravarty, Kristen E. Drake, Kelly D. Foote, Lisa Fosdick, Peter Giacobbe, Zoltán Mari, Mary Pat McAndrews, Cynthia A. Munro, Esther S. Oh, Michael S. Okun, J. Cara Pendergrass, Francisco A. Ponce, Paul B. Rosenberg, Marwan N. Sabbagh, Stephen Salloway, David F. Tang‐Wai, Steven D. Targum, David A. Wolk, Andrés M. Lozano, Gwenn S. Smith, Constantine G. Lyketsos
    Journal Name: Journal of Alzheimer's Disease
    Publisher: SAGE Publications
    Vol: 64
    Issue #: 2
    Start Page: 597
    End Page: 606
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3233/jad-180121
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6518401
    Citation Count: 101
  • Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients
    2011
    Summary Details
    OPEN
    Title: Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients
    Author(s): Hua She, Qian Yang, Kennie R. Shepherd, Yoland Smith, Gary W. Miller, Claudia Testa, Zixu Mao
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Vol: 121
    Issue #: 3
    Start Page: 930
    End Page: 940
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1172/jci43871
    Citation Count: 160
  • Comparison of enrollees and decliners of Parkinson disease sham surgery trials
    2012
    Summary Details
    OPEN
    Title: Comparison of enrollees and decliners of Parkinson disease sham surgery trials
    Author(s): Scott Y. H. Kim, Renée Wilson, Hyungjin Myra Kim, Robert G. Holloway, Raymond De Vries, Samuel Frank, Karl Kieburtz
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 27
    Issue #: 4
    Start Page: 506
    End Page: 511
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.24940
    Best OA location URL: https://hdl.handle.net/2027.42/90524
    Citation Count: 20
  • Association of SNCA with Parkinson: Replication in the Harvard NeuroDiscovery Center Biomarker Study
    2011
    Summary Details
    OPEN
    Title: Association of SNCA with Parkinson: Replication in the Harvard NeuroDiscovery Center Biomarker Study
    Author(s): Hongliu Ding, Alison K. Sarokhan, Sarah S. Roderick, Rachit Bakshi, Nancy Maher, Paymon Ashourian, Caroline G. Kan, Sunny Chun Chang, Andrea Santarlasci, Kyleen Swords, Bernard Ravina, Michael T. Hayes, U. Shivraj Sohur, Anne‐Marie Wills, Alice W. Flaherty, Vivek K. Unni, Albert Y. Hung, Dennis J. Selkoe, Michael A. Schwarzschild, Michael G. Schlossmacher, Lewis Sudarsky, John H. Growdon, Adrian J. Ivinson, Bradley T. Hyman, Clemens R. Scherzer
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 26
    Issue #: 12
    Start Page: 2283
    End Page: 2286
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23934
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3337217
    Citation Count: 25
  • Genetic modification of the association of paraquat and Parkinson's disease
    2012
    Summary Details
    OPEN
    Title: Genetic modification of the association of paraquat and Parkinson's disease
    Author(s): Samuel M. Goldman, Freya Kamel, G. Webster Ross, Grace S. Bhudhikanok, Jane A. Hoppin, Monica Korell, Connie Marras, Cheryl Meng, David M. Umbach, Meike Kasten, Anabel Chade, Kathleen Comyns, Marie Richards, Dale P. Sandler, Aaron Blair, J. William Langston, Caroline M. Tanner
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 27
    Issue #: 13
    Start Page: 1652
    End Page: 1658
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.25216
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3572192
    Citation Count: 94
  • Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease
    2008
    Summary Details
    OPEN
    Title: Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease
    Author(s): Christophe Lo Bianco, James Shorter, Etienne Régulier, Hilal A. Lashuel, Takeshi Iwatsubo, Susan Lindquist, Patrick Aebischer
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Vol: 118
    Issue #: 9
    Start Page: 3087
    End Page: 3097
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1172/jci35781
    Best OA location URL: http://www.jci.org/articles/view/35781/files/pdf
    Citation Count: 196
  • Screening for early detection of parkinsonism using a self-administered questionnaire: A cross-sectional epidemiologic study
    2013
    Summary Details
    OPEN
    Title: Screening for early detection of parkinsonism using a self-administered questionnaire: A cross-sectional epidemiologic study
    Author(s): Jessica I. Lundin, Harvey Checkoway, Susan R. Criswell, Angela Hobson, Rachel C. Harris, Laura Swisher, Bradley Evanoff, Brad A. Racette
    Journal Name: NeuroToxicology
    Publisher: Elsevier BV
    Vol: 45
    Issue #:
    Start Page: 232
    End Page: 237
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuro.2013.08.010
    Best OA location URL: http://doi.org/10.1016/j.neuro.2013.08.010
    Citation Count: 5
  • Pilot Single-Blind Trial of AbobotulinumtoxinA in Oromandibular Dystonia
    2018
    Summary Details
    OPEN
    Title: Pilot Single-Blind Trial of AbobotulinumtoxinA in Oromandibular Dystonia
    Author(s): Laura Scorr, Michael R. Silver, John Hanfelt, Elaine Sperin, Alan Freeman, Hyder A. Jinnah, Stewart A. Factor
    Journal Name: Neurotherapeutics
    Publisher: Elsevier BV
    Vol: 15
    Issue #: 2
    Start Page: 452
    End Page: 458
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s13311-018-0620-9
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s13311-018-0620-9.pdf
    Citation Count: 12
  • Central nervous system uptake of intranasal glutathione in Parkinson’s disease
    2016
    Summary Details
    OPEN
    Title: Central nervous system uptake of intranasal glutathione in Parkinson’s disease
    Author(s): Laurie K. Mischley, Kevin E. Conley, Eric G. Shankland, Terrance J. Kavanagh, Michael E. Rosenfeld, John E. Duda, Collin C. White, Timothy K. Wilbur, Prysilla U De La Torre, Jeannie M. Padowski
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 2
    Issue #: 1
    Start Page: 16002
    End Page: 16002
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/npjparkd.2016.2
    Best OA location URL: https://www.nature.com/articles/npjparkd20162.pdf
    Citation Count: 65
  • Different PD-MCI criteria and risk of dementia in Parkinson’s disease: 4-year longitudinal study
    2016
    Summary Details
    OPEN
    Title: Different PD-MCI criteria and risk of dementia in Parkinson’s disease: 4-year longitudinal study
    Author(s): Kyla-Louise Wood, Daniel J. Myall, Leslie Livingston, Tracy R. Melzer, Toni L. Pitcher, Michael R MacAskill, Gert J. Geurtsen, Tim Anderson, John C. Dalrymple‐Alford
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 2
    Issue #: 1
    Start Page: 15027
    End Page: 15027
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/npjparkd.2015.27
    Best OA location URL: https://www.nature.com/articles/npjparkd201527.pdf
    Citation Count: 83
  • Pathophysiology of manganese-associated neurotoxicity
    2011
    Summary Details
    OPEN
    Title: Pathophysiology of manganese-associated neurotoxicity
    Author(s): Brad A. Racette, Michael Aschner, Tomás R. Guilarte, Ulrike Dydak, Susan R. Criswell, Wei Zheng
    Journal Name: NeuroToxicology
    Publisher: Elsevier BV
    Vol: 33
    Issue #: 4
    Start Page: 881
    End Page: 886
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuro.2011.12.010
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3350837
    Citation Count: 134
  • A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy
    2014
    Summary Details
    OPEN
    Title: A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy
    Author(s): Franziska Richter, Sheila M. Fleming, Melanie B. Watson, Vincent Lemesre, Lee Pellegrino, Brian Ranes, Chunni Zhu, Farzad Mortazavi, Caitlin Mulligan, Pedrom C. Sioshansi, Sindalana Hean, Krystal De La Rosa, Richie Khanna, John J. Flanagan, David J. Lockhart, Brandon A. Wustman, Sean W. Clark, Marie‐Françoise Chesselet
    Journal Name: Neurotherapeutics
    Publisher: Elsevier BV
    Vol: 11
    Issue #: 4
    Start Page: 840
    End Page: 856
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s13311-014-0294-x
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s13311-014-0294-x.pdf
    Citation Count: 107
  • Use of a self-rating scale of the nature and severity of symptoms in Parkinson’s Disease (PRO-PD): Correlation with quality of life and existing scales of disease severity
    2017
    Summary Details
    OPEN
    Title: Use of a self-rating scale of the nature and severity of symptoms in Parkinson’s Disease (PRO-PD): Correlation with quality of life and existing scales of disease severity
    Author(s): Laurie K. Mischley, Richard Lau, Noel S. Weiss
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page: 20
    End Page: 20
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-017-0021-5
    Best OA location URL: https://www.nature.com/articles/s41531-017-0021-5.pdf
    Citation Count: 49
  • Quantitative neuropathology associated with chronic manganese exposure in South African mine workers
    2014
    Summary Details
    OPEN
    Title: Quantitative neuropathology associated with chronic manganese exposure in South African mine workers
    Author(s): Luis F. Gonzalez‐Cuyar, Gill Nelson, Susan R. Criswell, Pokuan Ho, Jaymes A. Lonzanida, Harvey Checkoway, Noah Seixas, Benjamin B. Gelman, Bradley Evanoff, Jill Murray, Jing Zhang, Brad A. Racette
    Journal Name: NeuroToxicology
    Publisher: Elsevier BV
    Vol: 45
    Issue #:
    Start Page: 260
    End Page: 266
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuro.2013.12.008
    Best OA location URL: http://doi.org/10.1016/j.neuro.2013.12.008
    Citation Count: 48
  • LRRK2 levels in immune cells are increased in Parkinson’s disease
    2017
    Summary Details
    OPEN
    Title: LRRK2 levels in immune cells are increased in Parkinson’s disease
    Author(s): Darcie A. Cook, George T. Kannarkat, Amarallys F. Cintron, Laura M. Butkovich, Kyle Fraser, Jianjun Chang, Nelly Grigoryan, Stewart A. Factor, Andrew B. West, Jeremy M. Boss, Malú G. Tansey
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page: 11
    End Page: 11
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-017-0010-8
    Best OA location URL: https://doi.org/10.1038/s41531-017-0010-8
    Citation Count: 306
  • Mechanism of parkin activation by PINK1
    2018
    Summary Details
    OPEN
    Title: Mechanism of parkin activation by PINK1
    Author(s): Christina Gladkova, Sarah Maslen, Mark Skehel, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 559
    Issue #: 7714
    Start Page: 410
    End Page: 414
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-018-0224-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6071873
    Citation Count: 400
  • Common genetic variant association with altered HLA expression, synergy with pyrethroid exposure, and risk for Parkinson’s disease: an observational and case–control study
    2015
    Summary Details
    OPEN
    Title: Common genetic variant association with altered HLA expression, synergy with pyrethroid exposure, and risk for Parkinson’s disease: an observational and case–control study
    Author(s): George T. Kannarkat, D A Cook, J-K Lee, Jianjun Chang, Julianne Chung, E Sandy, Kimberly C. Paul, Beate Ritz, Jeff M. Bronstein, Stewart A. Factor, Jeremy M. Boss, M G Tansey
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/npjparkd.2015.2
    Best OA location URL: https://escholarship.org/uc/item/48r6x3tj
    Citation Count: 163
  • Dentate nucleus iron deposition is a potential biomarker for tremor‐dominant Parkinson's disease
    2016
    Summary Details
    OPEN
    Title: Dentate nucleus iron deposition is a potential biomarker for tremor‐dominant Parkinson's disease
    Author(s): Naying He, Pei Huang, Huawei Ling, Jason Langley, Chunlei Liu, Bei Ding, Juan Huang, Hongmin Xu, Yong Zhang, Zhongping Zhang, Xiaoping Hu, Shengdi Chen, Fuhua Yan
    Journal Name: NMR in Biomedicine
    Publisher: Wiley
    Vol: 30
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/nbm.3554
    Best OA location URL: http://doi.org/10.1002/nbm.3554
    Citation Count: 63
  • Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    2009
    Summary Details
    OPEN
    Title: Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    Author(s): Kambiz N. Alavian, Paola Sgadó, Lavinia Albéri, Srinivasa Subramaniam, Horst H. Simon
    Journal Name: Neural Development
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page: 11
    End Page: 11
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/1749-8104-4-11
    Best OA location URL: https://neuraldevelopment.biomedcentral.com/counter/pdf/10.1186/1749-8104-4-11
    Citation Count: 41
  • Structure of PINK1 in complex with its substrate ubiquitin
    2017
    Summary Details
    OPEN
    Title: Structure of PINK1 in complex with its substrate ubiquitin
    Author(s): Alexander F. Schubert, Christina Gladkova, Els Pardon, Jane L. Wagstaff, Stefan M.V. Freund, Jan Steyaert, Sarah Maslen, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 552
    Issue #: 7683
    Start Page: 51
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature24645
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6020998
    Citation Count: 190
  • Pre- and Post- GPi DBS Neuropsychological Profiles in a Case of X-Linked Dystonia-Parkinsonism
    2011
    Summary Details
    OPEN
    Title: Pre- and Post- GPi DBS Neuropsychological Profiles in a Case of X-Linked Dystonia-Parkinsonism
    Author(s): Nobuko Kemmotsu, Catherine C. Price, Genko Oyama, Michael S. Okun, Kelly D. Foote, Laura L. S. Howe, Dawn Bowers
    Journal Name: The Clinical Neuropsychologist
    Publisher: Informa UK Limited
    Vol: 25
    Issue #: 1
    Start Page: 141
    End Page: 159
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1080/13854046.2010.532812
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3070298
    Citation Count: 8
  • Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    2017
    Summary Details
    OPEN
    Title: Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    Author(s): Malte Gersch, Christina Gladkova, Alexander F. Schubert, Martin A. Michel, Sarah Maslen, David Komander
    Journal Name: Nature Structural & Molecular Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 24
    Issue #: 11
    Start Page: 920
    End Page: 930
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nsmb.3475
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5757785
    Citation Count: 223
  • Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease
    2015
    Summary Details
    OPEN
    Title: Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease
    Author(s): Diego Mastroeni, Elaine Delvaux, Jennifer Nolz, Yuyan Tan, Andrew Grover, Salvatore Oddo, Paul D. Coleman
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 36
    Issue #: 12
    Start Page: 3121
    End Page: 3129
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.08.017
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4838454
    Citation Count: 61
  • Overview, hurdles, and future work in adaptive designs: perspectives from a National Institutes of Health-funded workshop
    2012
    Summary Details
    OPEN
    Title: Overview, hurdles, and future work in adaptive designs: perspectives from a National Institutes of Health-funded workshop
    Author(s): Christopher S. Coffey, Bruce Levin, Christina Clark, Cate Timmerman, Janet Wittes, Peter R. Gilbert, Sara Harris
    Journal Name: Clinical Trials
    Publisher: SAGE Publications
    Vol: 9
    Issue #: 6
    Start Page: 671
    End Page: 680
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1177/1740774512461859
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5570450
    Citation Count: 77
  • Abnormal calcium homeostasis and protein folding stress at the ER
    2011
    Summary Details
    OPEN
    Title: Abnormal calcium homeostasis and protein folding stress at the ER
    Author(s): Mauricio Torres, Gonzalo Encina, Claudio Soto, Claudio Hetz
    Journal Name: Communicative & Integrative Biology
    Publisher: Informa UK Limited
    Vol: 4
    Issue #: 3
    Start Page: 258
    End Page: 261
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.4161/cib.4.3.15019
    Best OA location URL: https://www.tandfonline.com/doi/pdf/10.4161/cib.4.3.15019?needAccess=true&role=button
    Citation Count: 41

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