7651 - 7675 of 9145 Results
Title
Year
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OPENTitle: Characterization of TAE684 as a potent LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 5Start Page: 1864End Page: 1869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.01.084Best OA location URL: http://hdl.handle.net/10871/35667Citation Count: 88
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OPENTitle: Genetic and Clinical Features of Progranulin-Associated Frontotemporal Lobar DegenerationJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 68Issue #: 4Start Page: 488End Page: 488Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2011.53Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3160280Citation Count: 121
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OPENTitle: Large-scale replication and heterogeneity in Parkinson disease genetic lociJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 79Issue #: 7Start Page: 659End Page: 667Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e318264e353Best OA location URL: https://n.neurology.org/content/neurology/79/7/659.full.pdfCitation Count: 132
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OPENTitle: Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 7Start Page: 2626End Page: 2631Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1318306111Best OA location URL: https://www.pnas.org/content/pnas/111/7/2626.full.pdfCitation Count: 367
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OPENTitle: Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1Journal Name: The EMBO JournalPublisher: Springer Science and Business Media LLCVol: 34Issue #: 22Start Page: 2840End Page: 2861Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.15252/embj.201591593Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.201591593Citation Count: 187
- Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative disease2008OPENTitle: Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative diseaseJournal Name: PROTEOMICS – Clinical ApplicationsPublisher: WileyVol: 2Issue #: 10-11Start Page: 1484End Page: 1497Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/prca.200800043Citation Count: 27
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OPENTitle: Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 DiabetesJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 10Start Page: e78577End Page: e78577Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0078577Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0078577&type=printableCitation Count: 10
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RESTRICTEDTitle: Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stressJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 102Issue #: 14Start Page: 5215End Page: 5220Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.0501282102Best OA location URL: http://doi.org/10.1073/pnas.0501282102Citation Count: 708
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions2010OPENTitle: Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusionsJournal Name: Nature GeneticsPublisher: Springer Science and Business Media LLCVol: 42Issue #: 3Start Page: 234End Page: 239Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ng.536Best OA location URL: http://doi.org/10.1038/ng.536Citation Count: 612
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OPENTitle: The microbiome of the human lower airways: a next generation sequencing perspectiveJournal Name: World Allergy Organization JournalPublisher: Elsevier BVVol: 8Issue #:Start Page: 23End Page: 23Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1186/s40413-015-0074-zBest OA location URL: http://www.worldallergyorganizationjournal.org/article/S1939455119302200/pdfCitation Count: 46
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OPENTitle: Molecular markers of early Parkinson's disease based on gene expression in bloodJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 104Issue #: 3Start Page: 955End Page: 960Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0610204104Best OA location URL: http://doi.org/10.1073/pnas.0610204104Citation Count: 517
- α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation2015OPENTitle: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 15Start Page: E1926End Page: 35Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1417883112Best OA location URL: https://www.pnas.org/content/pnas/112/15/E1926.full.pdfCitation Count: 150
- Stochastic electrotransport selectively enhances the transport of highly electromobile molecules2015OPENTitle: Stochastic electrotransport selectively enhances the transport of highly electromobile moleculesJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 46Start Page: E6274End Page: 83Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1510133112Best OA location URL: https://www.pnas.org/content/pnas/112/46/E6274.full.pdfCitation Count: 265
- CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo2015OPENTitle: CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 49Start Page: E6818End Page: 24Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1519430112Best OA location URL: https://www.pnas.org/content/pnas/112/49/E6818.full.pdfCitation Count: 30
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OPENTitle: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 28Start Page: 8756End Page: 8761Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1509742112Best OA location URL: https://www.pnas.org/content/pnas/112/28/8756.full.pdfCitation Count: 195
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 1Start Page: E34End Page: 43Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 127
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OPENTitle: Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 2Start Page: 636End Page: 641Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1220399110Best OA location URL: https://www.pnas.org/content/pnas/110/2/636.full.pdfCitation Count: 210
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OPENTitle: Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseasesJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 21Issue #: 15Start Page: 3500End Page: 3512Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/dds161Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3392107Citation Count: 237
- Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP12014OPENTitle: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 18Start Page: 6804End Page: 6809Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321845111Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/104291Citation Count: 215
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OPENTitle: Parkinson disease-associated mutation R1441H in LRRK2 prolongs the “active state” of its GTPase domainJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 11Start Page: 4055End Page: 4060Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1323285111Best OA location URL: https://www.pnas.org/content/pnas/111/11/4055.full.pdfCitation Count: 116
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OPENTitle: Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 113Issue #: 34Start Page: 9587End Page: 9592Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1610099113Best OA location URL: https://www.pnas.org/content/pnas/113/34/9587.full.pdfCitation Count: 266
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OPENTitle: Directed Differentiation of Dopaminergic Neuronal Subtypes from Human Embryonic Stem CellsJournal Name: STEM CELLSPublisher: Oxford University Press (OUP)Vol: 23Issue #: 6Start Page: 781End Page: 790Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1634/stemcells.2004-0365Best OA location URL: https://academic.oup.com/stmcls/article-pdf/23/6/781/40721656/stmcls_23_6_781.pdfCitation Count: 490
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OPENTitle: Rapid Generation of Functional Dopaminergic Neurons From Human Induced Pluripotent Stem Cells Through a Single-Step Procedure Using Cell Lineage Transcription FactorsJournal Name: Stem Cells Translational MedicinePublisher: Oxford University Press (OUP)Vol: 2Issue #: 6Start Page: 473End Page: 479Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.5966/sctm.2012-0133Best OA location URL: https://doi.org/10.5966/sctm.2012-0133Citation Count: 97
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OPENTitle: Advances in Therapeutic Options for Gait and Balance in Parkinson’s DiseaseJournal Name: US NeurologyPublisher: Touch Medical Media, Ltd.Vol: 07Issue #: 02Start Page: 100End Page: 100Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.17925/usn.2011.07.02.100Best OA location URL: http://www.touchneurology.com/wp-content/uploads/sites/3/2015/07/private_articles_10210_pdf_chou.pdfCitation Count: 20
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OPENTitle: Impaired dopamine release and synaptic plasticity in the striatum of PINK1 -deficient miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 104Issue #: 27Start Page: 11441End Page: 11446Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0702717104Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0702717104Citation Count: 539