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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2025
    Applying the Neuronal Alpha-synuclein Disease Integrated Staging System in Multiple System Atrophy

    Study Rationale: The neuropathological hallmark feature of Parkinson’s disease (PD) is the accumulation of a misfolded protein called alpha-synuclein in neurons, which qualifies PD as a neuronal...

  • Research Grant, 2025
    (SUPPLEMENT) Enhancing Brain Clearance Mechanisms to Limit Parkinson Disease Progression

    Study Rationale: Recent evidence has shown that people with Parkinson’s disease have a buildup of toxic proteins in their brains, as a result of impaired waste clearance mechanisms. Linked to this...

  • Research Grant, 2025
    Clinical Evaluation of 18F-FD4 as a Potential Alpha-synuclein PET Imaging Biomarker
  • iPSC Phenotyping Environmental Exposure Program, 2025
    Assessing PD-relevant Toxicants on Neurons and Microglia and their Crosstalk

    Study Rationale: We know that genetics plays a role in risk of Parkinson’s disease (PD) but does not explain every case, leading to the suggestion that genes work within the context of other exposures...

  • Seed Amplification Assay Innovation Program, 2025
    Quantitative SAA for Measuring Disease Progression in Parkinson’s Disease from Plasma

    Study Rationale: Parkinson’s disease (PD) is associated with the accumulation of clumped alpha-synuclein (asyn) protein in the brain. Detecting asyn in blood plasma could provide a less invasive and...

  • Seed Amplification Assay Innovation Program, 2025
    A Robust, Quantitative SAA and its Clinical Application

    Study Rationale: Seed Amplification Assays (SAA) have shown impressive results in distinguishing people with Parkinson's disease from healthy individuals using a simple yes/no test. This test detects...

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