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Funded Studies

Maria Grazia Spillantini, PhD

Professor of Molecular Neurology at University of Cambridge

Location: Cambridge United Kingdom

Born in Arezzo (Italy), Maria Grazia Spillantini, PhD, received a Laurea in Biological Sciences from Florence University and a PhD in Molecular Biology from Cambridge University. In 1996 she moved to the Department of Clinical Neurosciences at Cambridge University, where she was first a Lecturer, then a Reader, and now Professor of Molecular Neurology. Her interest is on tauopathies and alpha-synucleinopathies. With her collaborators, she identified alpha-synuclein as the component of the filaments that form the Lewy bodies in Parkinson’s disease, dementia with Lewy bodies and the glial inclusions in multiple system atrophy and described one of the first mutations in the MAPT gene causing frontotemporal dementia. She has received several awards, including the Potamkin Prize and the Jay Van Andel award for achievements in Parkinson’s disease. She is a Fellow of the Royal Society, the Academy of Medical Sciences, Clare Hall (Cambridge) and Knight Officer of the Star of Italy.

Associated Grants

  • Dissecting the Mechanisms Underlying Disease Progression


  • Overexpression of CSPalpha Using Viral Vectors in the Striatum of a-Syn 1-120 Transgenic Pre-clinicalModel


  • Targeting of Alpha-synuclein and SNARE Complex Dysfunction to Restore Synaptic Dopamine Release in a Model of Parkinson Disease Pathology


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