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1861 - 1870 of 8818 Results
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  • Organoid Cultures as Preclinical Models of Non–Small Cell Lung Cancer
    2019
    Summary Details
    OPEN
    Title: Organoid Cultures as Preclinical Models of Non–Small Cell Lung Cancer
    Author(s): Ruoshi Shi, Nikolina Radulovich, Christine Ng, Ni Liu, Hirotsugu Notsuda, Michael Cabanero, Sebastiao N. Martins‐Filho, Vibha Raghavan, Quan Li, Arvind Singh Mer, Joshua C. Rosen, Ming Li, Yu-Hui Wang, Laura Tamblyn, Nhu‐An Pham, Benjamin Haibe‐Kains, Geoffrey Liu, Nadeem Moghal, Ming‐Sound Tsao
    Journal Name: Clinical Cancer Research
    Publisher: American Association for Cancer Research (AACR)
    Vol: 26
    Issue #: 5
    Start Page: 1162
    End Page: 1174
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1158/1078-0432.ccr-19-1376
    Citation Count: 249
  • Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
    2020
    Summary Details
    OPEN
    Title: Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
    Author(s): Mathieu Bourdenx, Aurélien Nioche, Sandra Doveró, Marie-Laure Arotçarena, Sandrine Camus, Grégory Porras, Marie-Laure Thiolat, Nicolas P. Rougier, Alice Prigent, P. Aubert, Sylvain Bohic, Christophe Sandt, Florent Laferrière, Évelyne Doudnikoff, Niels Kruse, Brit Mollenhauer, Salvatore Novello, Michele Morari, Thierry Leste‐Lasserre, Inés Trigo‐Damas, Michel Goillandeau, Céline Perier, Cristina Estrada, Nuria García‐Carrillo, Ariadna Recasens, Nishant N. Vaikath, Omar M. A. El‐Agnaf, María Trinidad Herrero, Pascal Derkinderen, Miquel Vila, José Á. Obeso, Benjamin Dehay, Erwan Bézard
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 6
    Issue #: 20
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.aaz9165
    Best OA location URL: https://advances.sciencemag.org/content/advances/6/20/eaaz9165.full.pdf
    Citation Count: 53
  • Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease
    2020
    Summary Details
    OPEN
    Title: Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease
    Author(s): Lenora Higginbotham, Lingyan Ping, Eric B. Dammer, Duc M. Duong, Maotian Zhou, Marla Gearing, Cheyenne Hurst, Jonathan D. Glass, Stewart A. Factor, Erik C. B. Johnson, Ihab Hajjar, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 6
    Issue #: 43
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1126/sciadv.aaz9360
    Best OA location URL: https://advances.sciencemag.org/content/advances/6/43/eaaz9360.full.pdf
    Citation Count: 310
  • Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death
    2020
    Summary Details
    OPEN
    Title: Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death
    Author(s): Hyojung Kim, Jisoo Park, Hojin Kang, Seung Pil Yun, Yun‐Song Lee, Yun‐Il Lee, Yunjong Lee
    Journal Name: Science Signaling
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 13
    Issue #: 663
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scisignal.aax7119
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7909008
    Citation Count: 35
  • Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor
    2020
    Summary Details
    OPEN
    Title: Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor
    Author(s): Enrico Opri, Stephanie Cernera, Rene Molina, Robert S. Eisinger, Jackson Cagle, Leonardo Almeida, Timothy Denison, Michael S. Okun, Kelly D. Foote, Aysegul Gunduz
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 572
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aay7680
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8182660
    Citation Count: 120
  • Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion
    2020
    Summary Details
    OPEN
    Title: Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion
    Author(s): Sangwoo Ham, Seung Pil Yun, Hyojung Kim, Donghoon Kim, Bo Am Seo, Heejeong Kim, Jeong-Yong Shin, Mohammad Aasif Dar, Gum Hwa Lee, Yun Il Lee, Doyeun Kim, Sung‐Hoon Kim, Hee-Seok Kweon, Joo‐Ho Shin, Han Seok Ko, Yunjong Lee
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 569
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aax0091
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8082540
    Citation Count: 21
  • LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
    2020
    Summary Details
    OPEN
    Title: LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
    Author(s): Marco A. S. Baptista, Kalpana Merchant, Ted Barrett, Sakshi Bhargava, Dianne K. Bryce, J. Michael Ellis, Anthony A. Estrada, Matthew Fell, Brian Fiske, Reina N. Fuji, Paul Galatsis, Anastasia G. Henry, Sue Hill, Warren D. Hirst, Christopher Houle, Matthew Kennedy, Xingrong Liu, Matthew L. Maddess, Carrie G. Markgraf, Hong Mei, William A. Meier, Elie Needle, Stephen Ploch, Christopher M. Royer, Karin Rudolph, Alok Sharma, Antonia F. Stepan, Stefanus J. Steyn, Craig Trost, Zhizhang Yin, Hongshi Yu, Xiang Wang, Todd Sherer
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 540
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aav0820
    Citation Count: 114
  • A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease
    2020
    Summary Details
    RESTRICTED
    Title: A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease
    Author(s): Ibrahim Boussaad, Carolin D. Obermaier, Zoé Hanss, Dheeraj Reddy Bobbili, Silvia Bolognin, Enrico Glaab, Katarzyna Wicher, Nicole Weisschuh, Laura De Conti, Caroline May, Florian Giesert, Dajana Großmann, Annika Lambert, Susanne Kirchen, Maria Biryukov, Lena F. Burbulla, François Massart, Jill Bohler, Gérald Cruciani, Benjamin Schmid, Annerose Kurz-Drexler, Patrick May, Stefano Duga, Christine Klein, Jens C. Schwamborn, Katrin Marcus, Dirk Woitalla, Daniela M. Vogt Weisenhorn, Wolfgang Wurst, Marco Baralle, Dimitri Krainc, Thomas Gasser, Bernd Wissinger, Rejko Krüger
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 560
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aau3960
    Best OA location URL: http://orbilu.uni.lu/handle/10993/44767
    Citation Count: 41
  • Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates
    2020
    Summary Details
    OPEN
    Title: Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates
    Author(s): Matthew C. Deen, Cameron Proceviat, Xiaoyang Shan, Liang Wu, David L. Shen, G.J. Davies, David J. Vocadlo
    Journal Name: ACS Chemical Biology
    Publisher: American Chemical Society (ACS)
    Vol: 15
    Issue #: 4
    Start Page: 824
    End Page: 829
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acschembio.9b01044
    Citation Count: 10
  • Conopeptide-Functionalized Nanoparticles Selectively Antagonize Extrasynaptic N-Methyl-d-aspartate Receptors and Protect Hippocampal Neurons from Excitotoxicity In Vitro
    2020
    Summary Details
    OPEN
    Title: Conopeptide-Functionalized Nanoparticles Selectively Antagonize Extrasynaptic N-Methyl-d-aspartate Receptors and Protect Hippocampal Neurons from Excitotoxicity In Vitro
    Author(s): Pierluigi Valente, Darya Kiryushko, Silvio Sacchetti, Pedro Machado, Claire M. Cobley, Vincenzo Mangini, Alexandra E. Porter, Joachim P. Spatz, Roland A. Fleck, Fabio Benfenati, Roberto Fiammengo
    Journal Name: ACS Nano
    Publisher: American Chemical Society (ACS)
    Vol: 14
    Issue #: 6
    Start Page: 6866
    End Page: 6877
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acsnano.0c00866
    Best OA location URL: https://ndownloader.figstatic.com/files/22969427
    Citation Count: 14
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