The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Fast Track, 2002Pre-clinical Model for Pharmacological Upregulation of Molecular Chaperones
Lewy bodies including alpha-synuclein in substantia nigra neurons are characteristic of Parkinson's disease. These aggregates may cause the disease or may represent disease-causing protein folding...
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Fast Track, 2002The role of the DJ-1 gene in early-onset recessive Parkinson's Disease (PARK7)
Several families with rare genetic forms of Parkinson's disease have been identified, and at present mutations in three genes implicated in familial forms of parkinsonism have been described: the...
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The Role of Inflammation in Parkinson's Disease, 2003Spiral Inflammation Hypothesis of Parkinson’ Disease
It is well known that autopsied brains from patients with Parkinson's disease (PD) show evidence of inflammation within the region of the brain thought to be responsible for PD â€" the substantia...
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The Role of Inflammation in Parkinson's Disease, 2003Role of lymphocyte brain infiltration in neuroinflammation and nerve cell death in Parkinson’s disease
Parkinson's disease is characterized by a slow progression of a specific neuronal population in the brain using dopamine as neurotransmitter. Previous studies performed by several groups of...
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The Role of Inflammation in Parkinson's Disease, 2003Significance of Complement Activation in the Progression of Parkinson's disease
The complement system is composed of a series of proteins which react with each other in an orderly fashion, producing protein fragments (so-called 'complement activation proteins') which can exert...
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The Role of Inflammation in Parkinson's Disease, 2003Activation of Receptor for Advanced Glycation Endproducts (RAGE) on Microglia: A Novel Inflammatory Mechanism Contributing to PD Pathogenesis
There is now considerable and growing evidence that Parkinson's disease (PD) is associated with inflammation in the brain. Several small soluble proteins that are commonly secreted during inflammatory...
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Our funding programs support basic, translational and clinical research from academia and industry.