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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2020
    Identification of Therapeutic Circuits to Address Anxiety and Depression Symptoms in Parkinson’s Disease

    Study Rationale: Parkinson’s disease patients often experience depression and anxiety. Addressing these non-motor symptoms has not been the focus of Parkinson’s disease research though psychiatric...

  • Access to Data and Biospecimens, 2020
    Association of Repetitive DNA Elements in Parkinson’s Disease Risk and Progression

    Study Rationale:
    Repetitive DNA elements such as “jumping genes” were previously considered ‘junk DNA’. However, it is now known that these elements are involved in the development of several diseases...

  • Research Grant, 2019
    Long-acting GM-CSF Fusion Protein (PDM608) for the Treatment of Parkinson’s Disease

    Study Rationale:
    Emerging evidence suggests that the modulating the peripheral immune system can be a powerful disease-modifying approach for the treatment of Parkinson's disease (PD). We have...

  • Therapeutic Pipeline Program, 2019
    Oligomeric Alpha-synuclein-specific Antibody-based Gene Therapy

    Study Rationale:
    Alpha-synuclein is the primary component of Lewy bodies, the hallmark of Parkinson’s disease (PD). In particular, soluble aggregates of alpha-synuclein, also referred to as oligomers,...

  • Astrocyte Biology in Parkinson's Disease, 2019
    Astrocyte Gene Expression in Parkinson’s Interrogated Using Single Cell Nuclear RNA Sequencing

    Study Rationale:
    Astrocytes are one of the major non-neuron cell types in the brain and control many neurological processes. They are likely to be changed in Parkinson’s disease (PD) and may...

  • Astrocyte Biology in Parkinson's Disease, 2019
    Characterization of Astrocytes in Aging and Lewy Body Pathology

    Study Rationale:
    Astrocytes are brain cells with crucial roles, including communication between nerve cells, clearance of unwanted material, and response to injury. It has been suggested that astrocyte...

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