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Biospecimens

The Michael J. Fox Foundation makes data and biospecimens available from select Parkinson’s studies for discovery and validation research. Visit our Data page for resources from these and other studies. We also fund promising projects that use these data and biospecimen collections.

6 Types of Samples Available

  • Parkinson’s Progression Markers Initiative
    Population:
    De novo, unmedicated PD; prodromal; genetic; controls
    Request Samples For:
    Biomarker validation and verification
    Cohort Size
    1,500+

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

  • BioFIND
    Population:
    Moderate to advanced PD and controls
    Request Samples For:
    Biomarker discovery; replication
    Cohort Size
    ~200

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

  • LRRK2 Cohort Consortium
    Population:
    Genetic
    Request Samples For:
    Genetic PD and biomarker discovery/validation
    Cohort Size
    3,200

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

  • DATATOP
    Population:
    Early, unmedicated PD
    Request Samples For:
    Biomarker discovery and validation; understanding pharmacodynamics, pharmacogenetics, or disease progression
    Cohort Size
    800

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

  • 24-Hour Biofluid Sampling
    Population:
    Early to moderate PD and controls
    Request Samples For:
    Diurnal biomarker fluctuation; biomarker discover/validation; assay optimization; circadian fluctuations
    Cohort Size
    ~30

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

  • Arizona Parkinson's Disease Consortium
    Population:
    PD, other neurodegenerative diseases, neurologically normal elderly controls
    Request Samples For:
    Clinicopathological correlations
    Cohort Size
    450

    • Postmortem CSF

    • Postmortem Blood

    • Postmortem Tissue

Female researcher pipetting in lab.

Breaking Research Updates

Read the latest developments in the field’s understanding and treatment of Parkinson’s disease.

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