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Biospecimens

The Michael J. Fox Foundation makes data and biospecimens available from select Parkinson’s studies for discovery and validation research. Visit our Data page for resources from these and other studies. We also fund promising projects that use these data and biospecimen collections.

NOTE: If you have recently ordered biosamples, our biorepository has now resumed shipments and is providing estimated ship dates as well as confirming your ability to receive samples.

15 Types of Samples Available

  • Parkinson’s Progression Markers Initiative
    Population:
    De novo, unmedicated PD; prodromal; genetic; controls
    Request Samples For:
    Biomarker validation; Disease Progression; Understand genetic PD
    Cohort Size
    1,500+

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • BioFIND
    Population:
    Moderate to advanced PD and controls
    Request Samples For:
    Biomarker Discovery; Biomarker Replication
    Cohort Size
    ~200

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • LRRK2 Cohort Consortium
    Population:
    Genetic
    Request Samples For:
    Biomarker Discovery; Biomarker Replication; Disease Progression; Understand genetic PD
    Cohort Size
    3,200

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • DATATOP
    Population:
    Early, unmedicated PD
    Request Samples For:
    Biomarker Discovery; Biomarker Replication; Disease Progression; Pharmacogenetics/pharmacodynamics;
    Cohort Size
    800

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • 24-Hour Biofluid Sampling
    Population:
    Early to moderate PD and controls
    Request Samples For:
    Assay development/ validation; Biomarker Discovery; Biomarker Replication; Diurnal fluctuation
    Cohort Size
    ~30

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • Arizona Parkinson's Disease Consortium
    Population:
    PD, other neurodegenerative diseases, neurologically normal elderly controls
    Request Samples For:
    Clinicopathological correlations
    Cohort Size
    450

    • Postmortem CSF

    • Postmortem Blood

    • Postmortem Tissue

  • LRRK2 PBMC & Urine Biobank
    Population:
    Genetic PD
    Request Samples For:
    Assay development/ validation; Biomarker Discovery; Biomarker Replication; Biomarker validation; Understand genetic PD
    Cohort Size
    ~150

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • S4
    Population:
    early, moderate, advanced Parkinson's Disease patients and Healthy Controls
    Request Samples For:
    Biomarker Discovery; Biomarker Replication; Biomarker validation
    Cohort Size
    81

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • STEADY PD - 3
    Population:
    early idiopathic PD not requiring dopaminergic therapy
    Request Samples For:
    Pharmacogenetics/pharmacodynamics
    Cohort Size
    366

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • SURE PD - 3
    Population:
    early Parkinson's Disease
    Request Samples For:
    Pharmacogenetics/pharmacodynamics
    Cohort Size
    268

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • SURE PD - Phase 2
    Population:
    early Parkinson's Disease
    Request Samples For:
    Pharmacogenetics/pharmacodynamics
    Cohort Size
    75

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • PARS
    Population:
    At risk for Parkinson's disease
    Request Samples For:
    Biomarker Replication; Biomarker validation; Disease Progression;
    Cohort Size
    301

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • FS-Zone
    Population:
    early Parkinson's Disease
    Request Samples For:
    Cohort Size
    217

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • CERE-120
    Population:
    Parkinson's disease
    Request Samples For:
    Cohort Size
    148

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

  • AVE-8112
    Population:
    Parkinson's disease
    Request Samples For:
    Cohort Size
    13

    • DNA

    • RNA

    • CSF

    • Whole or Pellet Blood

    • Plasma

    • Serum

    • Urine

    • Saliva

    • Peripheral Mononuclear Blood Cells

    • Fibroblasts

    • Induced Pluripotent Stem Cells

    • Skin Tissue

    • Colon Tissue

    • Sub-Mandibular Gland Tissue

Male and female researcher wearing white lab coats chatting in the lab.

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