Funding Opportunities

Open Programs

• Accelerating Publication of Parkinson’s Disease Replication Data

  Objective:

  To address the bias toward the publication of novel positive results, The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and the Journal of Parkinson’s Disease (JPD) invite researchers to “open their notebooks” and submit unpublished results from experiments that attempted to replicate previously published findings from other laboratories.

  Award Amount:

  Manuscripts passing peer review will be published in JPD

  Due Date:

  Pre-Submissions Due: October 22, 2020, 5 p.m. US ET

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• Analysis of Patient-Reported Outcomes from Fox Insight

  Objective:

  This Request for Applications (RFA) seeks to fund analyses of the patient-reported outcomes (PROs) and genetic data collected through the Fox Insight study.

  Award Amount:

  Up to $100,000 for one year grants

  Due Date:

  Pre-Proposals Due: October 22, 2020

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• Development and Validation of Improved Outcome Measures

  Objective:

  The Michael J. Fox Foundation (MJFF) seeks applications to develop objective biomarkers that can support therapeutic development in Parkinson’s.

  Award Amount:

  Up to $750,000 for up to two years

  Due Date:

  Pre-Proposals Due: October 22, 2020

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• PIPETTE: 4R Tau and Alpha-Synuclein PET Tracer Development

  Objective:

  The PIPETTE Consortium (Philanthropic Investments in PET TracErs) is a funding partnership formed in 2017 by The Michael J. Fox Foundation and Rainwater Charitable Foundation (conveners of the Tau Consortium).

  Award Amount:

  Total funding available is $1 million

  Due Date:

  Pre-Proposals Due: October 22, 2020

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• Target Advancement Program

  Objective:

  The Michael J. Fox Foundation seeks applications that leverage and translate basic research to enable therapeutic development.

  Award Amount:

  Up to $150,000 for 18 to 24 months

  Due Date:

  Pre-Proposals Due: October 22, 2020

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• Therapeutic Pipeline Program

  Objective:

  The Michael J. Fox Foundation seeks applications with potential for fundamentally altering disease course and/or significantly improving treatment of symptoms above and beyond current standards of care.

  Award Amount:

  Up to $500,000 (pre-clinical) or up to $2 million (clinical)

  Due Date:

  Pre-Proposals Due: October 22, 2020

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• The Edmond J. Safra Fellowship in Movement Disorders

  Objective:

  Movement disorder specialists (neurologists with subspecialty training in Parkinson's disease and other movement disorders) serve as an important bridge between scientific advances in the lab and positive patient outcomes in the care setting.

  Award Amount:

  $90,000 per fellow per year

  Due Date:

  December 10, 2020

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Programs in Review

• Investigating Environmental Factors that Increase the Risk for Parkinson’s Disease

  Objective:

  The purpose of this Request for Applications (RFA) is to investigate environmental exposures, such as chemicals or toxic emissions, that increase the risk of PD and/or influence disease progression.

  Award Amount:

  Up to $400,000 for up to two years

  Due Date:

  Pre-Proposals Due: May 14, 2020

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• Target Advancement Program

  Objective:

  The Michael J. Fox Foundation seeks applications that leverage and translate basic research in order to enable therapeutic development. To this end, MJFF believes that promoting target and pathway validation studies within academic and industry laboratories can bridge the critical gap between basic biology and therapeutic development.

  Award Amount:

  Up to $200,000 for up to 18 months

  Due Date:

  Pre-Proposals Due: May 14, 2020

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• Parkinson’s Pathway Biomarkers

  Objective:

  The Michael J. Fox Foundation seeks applications with the potential to develop new/better biomarkers for measuring pathway function or dysfunction that can support therapeutic development for affected pathways in Parkinson’s disease (PD).

  Award Amount:

  Up to $300,000

  Due Date:

  Pre-Proposals Due: May 14, 2020

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• Therapeutic Pipeline Program

  Objective:

  The Michael J. Fox Foundation seeks applications with potential for fundamentally altering disease course and/or significantly improving treatment of symptoms above and beyond current standards of care.

  Award Amount:

  Up to $500,000 (pre-clinical) or $2 million (clinical)

  Due Date:

  Pre-Proposals Due: May 14, 2020

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• Occupational Therapy in Parkinson’s Disease Intervention

  Objective:

  This program seeks to fund research to investigate occupational therapy interventions in Parkinson's disease.

  Award Amount:

  Up to $100,000

  Due Date:

  May 15, 2020

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• BEAT-PD (Biomarker and Endpoint Assessment to Track Parkinson’s Disease) DREAM Challenge

  Objective:

  BEAT-PD is a data challenge designed to benchmark new methods to predict Parkinson’s disease progression. Specifically, its objective is to determine whether disease severity and progression can be assessed from passive sensor data collected during daily life.

  Award Amount:

  Winners share a $25,000 prize

  Due Date:

  May 13, 2020

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Closed Programs

• ASAP Collaborative Research Network

  

  Objective:

  The ASAP Collaborative Research Network, a program of the Aligning Science Across Parkinson’s (ASAP) initiative being implemented through The Michael J. Fox Foundation, seeks to support international, multidisciplinary, multi-institutional research teams to address key knowledge gaps in the basic disease mechanisms that contribute to Parkinson’s development and progression.

  Award Amount:

  Up to $9 million

  Due Date:

  Pre-proposals Due: January 8, 2020

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• Ken Griffin Alpha-synuclein Imaging Competition

  

  Objective:

  The Michael J. Fox Foundation has prioritized alpha-synuclein imaging as the most likely imaging approach to have an impact for therapeutic development. The goal of this $10-million funding program is to deliver a selective alpha-synuclein PET tracer for use in clinical studies.

  Award Amount:

  Up to $8.5 million

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• Therapeutic Pipeline Program

  Objective:

  The Michael J. Fox Foundation seeks applications with potential for fundamentally altering disease course and/or significantly improving treatment of symptoms above and beyond current standards of care.

  Award Amount:

  Up to $500,000 (pre-clinical) or $2 million (clinical)

  Learn more
• Use of Parkinson’s Disease Biosamples

  Objective:

  The Michael J. Fox Foundation seeks to facilitate access and use of our cohort biosamples. Applicants can request these human biosamples and associated grant funding for target validation or biomarker development programs.

  Award Amount:

  Up to $300,000

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• Biology of Astrocytes in Parkinson’s Disease

  Objective:

  The Michael J. Fox Foundation will award one-year to 18-month grants for studies that explore the role of astrocytes in Parkinson’s disease (PD) pathology and the potential for astrocyte-focused therapeutics. The goals of this funding program are to further understanding of astrocyte biology in Parkinson’s and to rationalize the pursuit of astrocyte-specific targets and/or pathways for the treatment of the disease.

  Award Amount:

  Up to $150,000

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• Assay Development and Validation for Quantifying Oligomeric Alpha-Synuclein

  Objective:

  The Michael J. Fox Foundation will award one-year grants for research to advance the development, optimization and validation of assays to quantify oligomeric alpha-synuclein in human body fluids. Prior research suggests that alpha-synuclein quantification in accessible body fluids may serve as a biomarker of disease diagnosis, target engagement, pharmacodynamic response and/or patient stratification.

  Award Amount:

  Up to $200,000

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• Imaging Biomarkers to Track Disease Progression and Therapeutic Efficacy

  Objective:

  The Michael J. Fox Foundation will award one- to three-year grants to develop imaging markers for use in disease-modifying clinical trials. Imaging is a powerful tool that can be used to visualize the structure and function of the brain in living subjects. While a variety of imaging techniques are available, none have been demonstrated to be a sensitive, specific and reliable biomarker test for the presence and progression of PD.

  Award Amount:

  Up to $750,000

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• Therapeutic Pipeline Program

  Objective:

  The Michael J. Fox Foundation seeks applications with potential for fundamentally altering disease course and/or significantly improving treatment of symptoms above and beyond current standards of care. The Therapeutic Pipeline Program is an Edmond J. Safra Core Program for PD Research.

  Award Amount:

  Up to $500,000 (pre-clinical or applied tech) or up to $2 million (clinical)

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