The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Biomarkers, 2009Development of an mGluR5 Imaging Marker for Parkinson's Disease
Objective/Rationale:
The goal of this proposal is to develop an imaging test, 18F-PEB PET, to assess glutamate function in the brain of individuals with Parkinson disease (PD) and determine if the... -
Biomarkers, 2009High Resolution Diffusion Tensor MRI Imaging as a Biomarker of Parkinson's Disease Diagnosis and Disease Progression
Objective/Rationale:
As Parkinson’s disease (PD) is moving into the era of neuroprotective interventions one of the major objectives is the development of a biomarker of PD diagnosis. This study... -
Biomarkers, 2009Development of an alpha6*-Selective Neuronal Nicotinic Receptor (NNR) Imaging Agent as a Parkinson's Disease Biomarker
Objective/Rationale:
The availability of a selective PET radiotracer for the drug target is critical for determining receptor occupancy in humans. NNR subtypes containing the alpha? subunit have been... -
MJFF Research Grant, 2008Pharmacodynamic Biomarkers of Drug-induced Protein Clearance in Rodent Cerebrospinal Fluid
Objective/Rationale:
Parkinson’s disease is, at least in part, a disease caused by misfolding and aggregation of the protein alpha-synuclein. Boosting the natural degradation machinery of diseased... -
Biomarkers, 2009High Resolution Diffusion Tensor Imaging in Parkinson's Disease and Parkinson Plus Syndromes
Objective/Rationale:
An objective and valid trait and state biomarker of Parkinson’s disease will help therapeutic development by providing a measure to help confirm diagnosis (trait), and track... -
Rapid Response Innovation Awards, 2009Possibility of Small Molecule Activation of PINK1 Kinase Activity
Objective/Rationale:
Many genetic disorders are caused by the loss of a functional protein which protects cells from disease. These disorders are difficult to treat with drugs because most drugs block...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.