The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2010Pharmacodynamics and Neuroprotective Effects of Pegylated G-CSF
Promising Outcomes of Original Grant:
We have discovered that a specific protein, granulocyte-colony stimulating factor (G-CSF), is effective in reducing nerve cell death and thereby disease... -
Rapid Response Innovation Awards, 2009Generation of Dorsal Motor Nucleus (DMN) Specific Pre-clinical Model of Alpha-Synuclein Overexpression to Study Etiology of Autonomic Dysfunction in PD
Promising Outcomes of Original Grant:
According to Braak Staging of PD Pathology, the dorsal motor nucleus (DMN) is one of the earliest brain nuclei that accumulate alpha-Synuclein (aSyn) pathology... -
Target Validation, 2007Development of Lentiviral DN-TNF Vectors: A Novel Anti-inflammatory Gene Therapy to Block Nigrostriatal Degeneration
Objective/Rationale:
A growing number of epidemiological and experimental animal studies implicate neuroinflammatory mechanisms in the progressive death of midbrain dopamine (DA) neurons in Parkinson’s...
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Specification, Patterning, and Maintenance of Midbrain Dopam, 2006Generation of Midbrain Dopamine Neurons from Human ES Cells by Forced Expression of Lmx1a
Drs. Ericson and Perlmann have identified two key transcription factors (Lmx1a and Msx1) that regulate early development of dopamine neurons and can induce nearly 90% ‘authentic’ dopamine neurons when...
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Clinical Intervention Awards, 2007Serotonin and Sleep Disordered Breathing in Parkinson Disease
Objective/Rationale:
Sleep related problems are a major cause of impairment in Parkinson's disease. Recent studies indicate a high incidence of a disabling sleep disorder – sleep disordered breathing... -
Clinical Intervention Awards, 2007The PARKFIT Study: Effectiveness of an Active Lifestyle Promotion Program for Patients with Parkinson’s disease
Objective/Rationale:
Parkinson's patients are inclined toward a sedentary lifestyle. This is due to a combination of both physical handicaps (e.g. walking difficulties) and mential impairments (e.g...
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Our funding programs support basic, translational and clinical research from academia and industry.