The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutics Development Initiative, 2012Lead Optimization for a Parkinson's Disease Therapeutic
Objective/Rationale:
CuII(atsm) has the potential to delay disease progression in Parkinson’s disease, based on extensive pre-clinical model data. CuII(atsm) has been shown to significantly improve... -
ASAP CRN Discovery Fellowship 2025, 2026Does Pathogenic α-Synuclein Disrupt Lipid Droplet–Mitochondria Coupling in Parkinson’s Disease?
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Summer 2025 RFA: Personalized Approaches for Understanding, Assessing and Improving Gait in Parkinson’s Disease Research Program, 2026ADAPT-GAIT: Adaptive deep brain stimulation controlled by neural biomarkers of gait to alleviate locomotor deficits in people with advanced Parkinson's disease
Study Rationale:
People with advanced Parkinson’s disease often develop severe gait and balance impairments—including asymmetries, instability, and freezing of gait—that are heterogeneous...
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Clinical Intervention Awards, 2007The PARKFIT Study: Effectiveness of an Active Lifestyle Promotion Program for Patients with Parkinson’s disease
Objective/Rationale:
Parkinson's patients are inclined toward a sedentary lifestyle. This is due to a combination of both physical handicaps (e.g. walking difficulties) and mential impairments (e.g... -
Resource: Utilizing DATATOP Biospecimens, 2011Validation of Alpha-synuclein Oligomers as Biomarker for Parkinson’s Disease
Objective/Rationale:
We have reported recently higher levels of α-synuclein oligomers species in cerebral spinal fluid (CSF) from patients clinically diagnosed with Parkinson’s disease (PD) versus... -
Critical Challenges in PD: Alpha-synuclein Neuroimaging, 2009Utility of the Amyloid Ligand [18F]FDDNP in Human PET Imaging in Parkinson Disease
Objective/Rationale:
Biomarkers of Parkinson disease are sorely needed for the assessment of disease status so that they may be used to design more efficient and informative clinical trials of disease...
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Our funding programs support basic, translational and clinical research from academia and industry.