The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2013Topography of Vulnerability to Alpha-synuclein Fibrils in the Cerebral Cortex
Objective/Rationale:
In Parkinson’s disease, the neocortex (outer layer of the brain’s cerebral hemispheres, made of six layers) is less vulnerable than the allocortex (fewer than six... -
LRRK2 Cohort Consortium, 2013Gender Differences in LRRK2 Mutation and Non-LRRK2 Mutation PD, and Expression of LRRK2 Mutations
Objective/Rationale:
In Western populations, men are approximately 1.5 times more likely to develop Parkinson’s disease (PD) than women. Furthermore, epidemiologic and clinical features of PD vary... -
Postural Instability and Gait Disturbances, 2009Role of the Posterior Parietal Cortex and Pedunculopontine Nucleus in the Pathophysiology of Freezing of Gait: An MRI and TMS Study
Objective/Rationale:
Although disturbances in the posterior parietal cortex (PPC) and pedunculopontine nucleus (PPN) are thought to be involved in the development of freezing of gait (FOG) in PD... -
Improved Neuromodulation Approaches, 2014Adaptive Closed Loop Neuromodulation and Neural Signatures of Parkinson’s Disease
Study Rationale:
Currently deep brain stimulation (DBS) is limited to “open-loop” stimulation, without real-time adjustment to the patient’s state of activity, fluctuations and types of motor symptoms...
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Our funding programs support basic, translational and clinical research from academia and industry.