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Funding Opportunities

Development and Validation of Improved Outcome Measures


The Michael J. Fox Foundation (MJFF) seeks applications to develop objective biomarkers that can support therapeutic development in Parkinson’s.

These may include biomarkers that improve definitive diagnosis, objectively track disease progression, enrich for subject populations, or more precisely detect a treatment response or target engagement. The availability of these types of biomarkers would transform clinical trial design and assist in the interpretation of trial results.

What Fits

Applications should focus on studies that achieve one or more of the following for Parkinson’s:

  • Develop or validate promising biomarkers of disease
  • Develop or validate prodromal biomarkers
  • Develop or validate biomarkers of phenoconversion
  • Develop or validate specific molecular biomarker assays
  • Analyze and derive candidate biomarkers from existing biological datasets
  • Develop and support remote assessment strategies that could complement in clinic assessments

This program is not appropriate for:

  • Therapeutic development
  • Interventional studies
  • Literature/landscape review or assessment

Informational Webinar

Watch our informational webinar on-demand to learn more about our Foundation's funding strategy and opportunities, and the application and review processes. Watch now.

Application Process

  1. Download the RFA and application template.
  2. Log in or create account in the grant application portal.
  3. Submit your completed application.

Please note we made changes to our publication and indirect costs policies in early 2020. Review the updated Application Guidelines and the new open access publication policy for complete details. Contact with questions about the RFA, application process, or these policies.

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