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Andrew West, PhD

Professor of Pharmacology and Cancer Biology, Cell Biology, Neurology, and Neurobiology at Duke University School of Medicine
Location: Durham, NC United States

Dr. West serves as the Lead Investigator for the team proposal “Decoding α-Synuclein Conformational Diversity to Enable Advanced Predictive Amplification Assays.” He is the Director of the Duke Center for Neurodegeneration and Neurotherapeutics and leads a multidisciplinary laboratory focused on mechanisms of neurodegenerative disease, biomarker discovery, and disease-modifying therapeutic strategies. Dr. West is a founding member of the NINDS Parkinson’s Disease Biomarker Program (PDBP) Steering Committee, a former member of the Michael J. Fox Foundation Executive Scientific Advisory Board, and a reviewing editor for neurodegeneration research at eLife. Over the past decade, he has led multiple large, successful multidisciplinary initiatives supported by NINDS, MJFF, Udall Centers, and ASAP, with a focus on α-synuclein and LRRK2 biology, assay development, and biomarker discovery. He has over 25 years of experience in α-synuclein research and has authored more than 100 largely open-access publications.


Associated Grants

  • Characterization of LRRK2 Monoclonal Antibodies in Pre-clinical Brain Tissue

    2011


  • LRRK2 Dimerization as Pharmacodynamic Biomarkers of Activity

    2010


  • Delivery of Kinase-Modified LRRK2 to Dopaminergic Neurons Using High-Capacity Viral Vectors

    2009


  • Delivery of Kinase-Modified LRRK2 to Dopaminergic Neurons Using High-Capacity Viral Vectors

    2007


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