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Luis Bonet-Ponce, PhD

Assistant Professor, Department of Neurology at The Ohio State University
Location: Columbus, OH United States

Dr. Bonet-Ponce obtained his BS and MS degrees from the Universidad de Valencia in 2011 and 2012 respectively. He then joined the Universidad Catolica de Valencia and earned his PhD in 2015, studying the effect of ROS in selective autophagy. During his postdoctoral training in Dr. Mark Cookson’s lab at the NIH, Dr. Bonet-Ponce discovered the recruitment of LRRK2 to membrane-damaged lysosomes, which triggers a process called LYTL (LYsosomal Tubulation/sorting driven by LRRK2). In September 2023, he established his own lab at The Ohio State University. The Bonet-Ponce lab uses molecular biology techniques, including advanced microscopy and unbiased screenings, to study the role of lysosomal dysfunction in PD.


Associated Grants

  • Deciphering Intracellular Pathways Altered by LRRK2 Kinase Activity and Phospho-RAB Effector Function

    2026


  • Toward an Atlas of Endolysosomal System Dysfunction with PD-associated Channels/Transporters

    2026


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