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Funded Studies

Pamela J. McLean, PhD

Associate Professor at Mayo Clinic Jacksonville

Location: Jacksonville, FL United States

Pam McLean, PhD is an associate professor of neuroscience at the Mayo Clinic in Jacksonville and the director of the Neurobiology of Disease Program at Mayo Graduate School/Mayo College of Medicine. She received her PhD from Boston University School of Medicine in 1998 and spent 15 years at Massachusetts General Hospital (MGH), first as a postdoctoral fellow and then as faculty. During her time at MGH she established her research program in Parkinson’s disease with a focus on the neurobiology of alpha-synuclein.

Her research uses state-of-the-art cell-based assays, novel imaging techniques, and pre-clinical models to investigate molecular mechanisms underlying neurodegeneration in PD, dementia with Lewy bodies and related disorders. Dr. McLean has published extensively and her research is currently supported by the National Institutes of Health and The Michael J Fox Foundation. 

Associated Grants

  • Developing Disease-modifying Chemical Probes to Inhibit Alpha-synuclein Accumulation


  • Disease-modifying Chemical Probes to Inhibit Alpha-synuclein Aggregation


  • Development and screening of contrast agents for in vivo imaging of Parkinson's Disease


  • Development and Screening of Contrast Agents for In Vivo Imaging of PD


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