Sang-Hyun Oh, PhD is a McKnight University Professor and Sanford P. Bordeau Chair at the University of Minnesota. Trained in Physics at Korea Advanced Institute of Science and Technology (KAIST) and Stanford (PhD, Applied Physics), he has led research at the intersection of nanotechnology and biosensing for over two decades. Motivated by personal loss to neurodegenerative disease, his lab develops ultrasensitive, noninvasive diagnostic platforms for early detection of Parkinson’s and related synucleinopathies. Dr. Oh’s innovations in seed amplification assays, biosensing, and label-free imaging have been featured in over 160 publications. He is Editor-in-Chief of npj Biosensing and a Fellow of Optica. His current focus is on advancing blood-based RT-QuIC platforms, including Nano-QuIC, toward enabling rapid, same-day diagnostics. In collaboration with NIH and Mayo Clinic partners, he is committed to translating these technologies into widely accessible tools that transform clinical care and disease monitoring for Parkinson’s patients worldwide.
Associated Grants
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Blood-based Same-day Nano-QuIC for Rapid Detection of Misfolded Alpha-synuclein in Parkinson's Disease
2025