Xianjun Dong, PhD

Dr. Xianjun Dong is an Associate Professor of Neurology and of Biomedical Informatics and Data Science at Yale School of Medicine. He directs the Dong Lab (www.donglab.org) at the Stephen and Denise Adams Center for Parkinson’s Disease Research, where his team combines large-scale human genomics, artificial intelligence, and experimental models to uncover how genes and regulatory networks drive Parkinson’s disease and related disorders. His lab develops computational frameworks for enhancer-gene mapping, drug repurposing, and extracellular vesicle transcriptomics, translating genomic discoveries into mechanistic and therapeutic insights. Before joining Yale in 2024, Dr. Dong was on the faculty at Harvard Medical School and Brigham and Women’s Hospital, where he established his independent lab and led the Genomics and Bioinformatics Hub. His group collaborates broadly to build open, data-driven platforms that accelerate discovery and move the field toward precision medicine for Parkinson’s disease.