… Photo caption: Amy Helein and her husband, Gary, at their … and lessons learned. Our takeaway: be optimistic, form a committee, never give up, and welcome change. Team Fox: Your husband has had Parkinson’s since he was 29. How have your lives changed since his diagnosis? Amy Helein: …

… is frequently mutated in Parkinson’s disease. It is known to be involved in getting rid of damaged mitochondria in … properties of the engineered protein will depend upon how close these elements are to each other. Combined with a powerful microscope we will be able to …

… Study Rationale: Age is the biggest risk factor for Parkinson's disease (PD), with disease incidence … can cause neurodegeneration and inflammation. Damage to DNA and mitochondria (cell's energy generators) - both known … of the brain most affected by PD, the substantia nigra pars compacta (SNc). Hypothesis: In the proposed study, we will …

… Study Rationale: Mutations in the LRRK2 gene are the most common inherited cause of Parkinson’s disease. These changes affect how cells read and process genetic messages, producing … we will study several disease-causing mutations in LRRK2 to see which isoforms are most affected. We will then test …

… Editor's Note: For more Foundation news and research updates, … and her father had Parkinson's disease (PD). She made a commitment to research by joining clinical studies, … to help science. I wasn't even thinking that I was going to get a disease. It just never occurred to me." Genetic …

… Study Rationale:        An early diagnostic test to identify those with Parkinson’s disease (PD) and to intervene with therapies as early as possible is a …