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Winning Data Challenge Entry Seeks to Use ‘Machine Learning Approach’ to Improve the Monitoring of Parkinson’s Disease
April 24, 2013
… LIONsolver team members, from left, Dr. Roberto Battiti, Drake Pruitt, Dr. Mauro Brunato In February, The … learning” is, his team’s motivation for entering the competition, and their hopes for developing practical … allows computers to build powerful models and improve their predictions by learning from the data itself. The results …
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Takeaways from Talking to 50 Parkinson's Experts
June 29, 2018
… Benjamin Stecher is taking an investigative approach to his own Parkinson's diagnosis. He writes in a new blog … (MJFF) advisors and grantees. MJFF CEO Todd Sherer, PhD, commented on the shift to understand and treat Parkinson's … its clinical symptoms, which could help develop and test precision medicine approaches. "We need to move this beyond …
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Foundation Publishes Roadmap for Researchers to Recruit Trial Volunteers
February 20, 2014
… We speak to patients about clinical research participation in our … on how to engage with potential participants. The article recommends that researchers: Involve patients: Convene a … study — whether you have Parkinson’s disease or not — visit Fox Trial Finder, an online tool to match studies with …
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Podcast: Improved Levodopa Delivery with Inhaled Formulation
June 18, 2013
… Many people with Parkinson’s on a levodopa regimen face "off" periods, … effects of the medication wear off before they are ready to take their next dose. For this reason, The Michael J. Fox … a puff from an inhaler should they feel an "off" period coming on. Development of CVT-301 is moving forward …
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Xenon inhalation to reduce L-Dopa-induced dyskinesia
… Objective/Rationale: Levodopa is the most effective drug to treat symptoms of Parkinson’s disease, however long-term … have been shown to be efficacious in reducing LID in pre-clinical and clinical models. Xenon, a noble gas with … mixture will be administered to the pre-clinical models in combination with levodopa, followed by an evaluation of …
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Development of SHG to Discover Drugs to Selectively Block AlphaS toxicity
… conformation. Using this technology, he will create a laboratory screening assay that can be used to screen for compounds that can block abnormal changes in … be used in large-scale drug screening approaches. Final Outcome Dr. Salafsky successfully developed his screening assay …