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From Anti-aggregation Assay to Treatment for Parkinson's Disease: Developing a Secondary Screen to Bridge High throughput Screen and Cellular Assay
… Objective/Rationale: We want to develop a series of secondary assays that will allow us … on cellular assays, which will involve around a hundred compounds. Project Description: Aggregation of the protein … throughput assay selects compounds for their ability to prevent this aggregation under one specific set of …
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Reaching the Peak with Parkinson's and an Extra Measure of Grit
April 19, 2018
… 25, 2016, I entered into the Parkinson's disease (PD) community at 48 years old. In the months that followed, I … but hours later, I stood on a bridge a few dozen feet from where the water tumbled over the top of Nevada Falls. … Hike and to view more of his photography from the mountain, visit his blog at NevadaFalls2000.com . Steve Green …
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The Appendix: What's the Link to Parkinson's?
May 10, 2019
… suggests that having your appendix removed (an appendectomy) is associated with an increased risk of Parkinson’s … happens in science, these results are inconsistent with a previous study that came to the opposite conclusion : that … with a decreased risk of PD. But what these studies have in common is demonstrating an association between the appendix …
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The Role of the Transcriptome in PD: A Novel Approach to PD Therapeutics
… in need of new biomarkers and effective therapies. To date, most of the studies have focused on DNA and … study these ignored molecules to find new therapies using a computational approach. Hypothesis: We hypothesize that … PD and controls to identify differentially expressed transcripts, integrate the different transcript …
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100 Days, 100 Ways to Support Parkinson's Research
September 23, 2014
… As of today, only 100 days remain in 2014. With fall in full swing … campaign to showcase the hundreds of ways our fundraising community is helping to speed a cure for Parkinson’s … Register for our upcoming webinar (September 30, 1PM) where we’ll be sharing ideas and providing support to get …
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A Personal Responsibility to Meet the Brin Wojcicki Challenge
April 9, 2012
… Did you know that you can become a part of the Brin Wojcicki Challenge through an anonymous gift? Here’s the story of one anonymous Challenge donor, published in the … a personal cause for me. As I began looking into how and where to make meaningful contributions to Parkinson’s …