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Regulated rAAV-GDNF to treat Parkinson's disease: Translational research plan
… Disease Objective/Rationale : We are attempting to perfect gene therapy using glial cell line-derived … engineering the ability to turn off GDNF delivery using the common antibiotic, doxycycline. There are some significant … of Parkinson’s disease (PD). Unfortunately, clinical trials where GDNF was injected directly into the brain or gene …
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Parkinson’s and Environmental Risk: A Q&A with Dr. Caroline Tanner
September 4, 2025
… Plan , a new book detailing environmental and lifestyle factors in Parkinson’s disease (PD), is generating buzz among … a strong genetic cause. So what tips the balance? That’s where environmental exposures come into play. It could be what you eat, what kind of work …
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Upregulation of Autophagy by Tet3-mediated 5-methylcytosine oxidation – Relevance to Parkinson's Disease
… down) alpha-synuclein and are involved in the lysosome-autophagy system (LAS). During aging, changes in DNA methylation (the process of regulating gene expression) have been suggested to turn "off" LAS genes. This …
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Expanding the Picture of Parkinson’s through BLAAC PD: Q&A with Dr. Erin Foster
January 12, 2026
… Foster, second from the right. Black and African American communities have long been underrepresented in … making participation easier through a one-time, 90-minute visit and offering compensation for volunteers’ time, BLAAC … today and shape a better future for Black families everywhere. Below, we speak with Erin Foster, PhD, OTD, OTR/L, …
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VIDEO: Get Involved in Clinical Research to Help Speed a Cure!
October 15, 2013
… know that clinical trials are a crucial step on the path to developing new and better treatments for Parkinson's … to read stories from real people who have participated, test your knowledge with our Clinical Trials IQ Quiz , and … up for a lack of clinical trial volunteers. Get involved by visiting www.michaeljfox.org/clinicaltrials today! …
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Michael J. Fox Honored with Presidential Medal of Freedom
January 4, 2025
… honor recognizes his tireless advocacy and dedication to speeding a cure for Parkinson’s disease NEW YORK … and for all.” Founded by Fox in 2000, MJFF has grown to become the world’s largest nonprofit funder of Parkinson’s … of Team Fox members around the world. For more information, visit us at www.michaeljfox.org , Facebook , Instagram …