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A Personal (and Professional) Mission to Cure Parkinson's
August 10, 2017
… experience with strategic investment in drug development. However, Jonathan's sense of urgency to find cures intensified after he received a diagnosis of … at age 49. In recent years, the genetic target GBA has come to the forefront of Parkinson's disease (PD) research. …
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News in Context: Trial Tests Focused Ultrasound for Parkinson’s Motor Symptoms
January 15, 2021
… A new approach to focused ultrasound (FUS) for Parkinson’s is in the news. … shaking of the hands, head or voice. In these cases, FUS targets a part of the brain called the thalamus. Researchers … 40 participants, 27 had focused ultrasound of the STN. For comparison, the others had a “sham” procedure, which mimics …
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Consortium to Develop an Alpha-Synuclein Imaging Agent
August 9, 2012
… 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain - Baltimore The Michael J. … (BioFocus). These groups are working to identify and test compounds that can ultimately be radiolabeled and used as … the Thioflavin T screen, approximately 2,000 compounds showing >45% inhibition of binding were selected for hit …
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Parkinson's Diagnosis Yields a New Opportunity to Do Good
September 26, 2012
… in which we highlight someone who inspires us on their path toward a cure. Bill Burton, of New Britain, Connecticut, had … he had Cubital Tunnel Syndrome, meaning his ulnar nerve was compressed in his elbow. As his symptoms continued to … Michael J. Fox Foundation, prior to PPMI he hadn’t realized how much research was enabling. He completed a profile on …
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Using Ketamine to Treat Depression in Parkinson’s Disease
… around half of people with Parkinson’s disease (PD). However, existing antidepressants are not effective in treating these symptoms in PD and new treatments are urgently needed. Ketamine, … how it works in the brain. Hypothesis: We hypothesize that, compared to a placebo, a course of ketamine treatment will …
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Recording Brain Activity Could Lead to Personalized Deep Brain Stimulation
February 11, 2014
… questions about the current state of this therapy for the motor symptoms of Parkinson’s disease (PD). For DBS, a surgeon … Watch our Webinar on DBS and other surgical interventions. However, researchers believe they can improve the technology … brain need to be able to adjust their activity patterns and communicate with one another. One way this happens is with …