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Klotho and Parkinson’s disease
… Genetic studies have identified a powerful “aging suppressor gene”, Klotho, that may play a role in delaying … tissue functioning. Klotho has been detected in the circulatory system of both animals and humans. Although Klotho … have been reported in individuals with Alzheimer’s disease compared to older adults with no loss of cognition. Though …
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Parkin Modulates Neuroinflammation to Sustain Dopaminergic Neuronal Health
… cells of people with Parkin mutations impairs their ability to repair the dopamine neurons damaged in PD. Project Description: Pre-clinical models with and without the parkin protein will be introduced a toxin into the brain region that becomes damaged during Parkinson’s disease. The response of …
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NYC-Come spin with Team Fox!
January 6, 2012
… on the Upper East Side will be hosting a charity ride with 100% of the proceeds raised coming to the Foundation. 45 bikes are available ($150 donation …
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More Peaks, Fewer Valleys with Levodopa
June 19, 2014
… June 19, 2014 Duration: 1 hr Time: 12:00 pm ET A person with Parkinson's, a neurologist and a researcher discuss … associated with Parkinson's medication and research to treat or avoid the debilitating motor fluctuations that can arise with long-term PD medication …
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Connecting the Environmental Exposome to PD Risk and Disease Pathology
… many cases of Parkinson’s disease are caused by exposure to harmful chemicals and pesticides in the environment. … why many people still get Parkinson’s, even in countries where we thought we removed some of the worst … and we will select the worst chemicals for testing in preclinical models. With a team of environmental chemists, …
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Use of Neuromodulation to Relieve Gait Freezing in Parkinson’s Disease
… episodes of freezing of gait, which is a sudden inability to take a step while walking. Gait freezing can cause falls … and possibly mortality, and it is associated with depression, social isolation and stigma. Current treatments … but do not treat gait freezing. In this study, we will test the accuracy of a new algorithm for detecting gait …